Health Sciences, Pharmacology.
概要
作品: | 371 作品在 0 項出版品 0 種語言 |
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書目資訊
Regulation of interferon alphabeta induction and dendritic cell function by CpG oligodeoxynucleotides.
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MicroRNA regulation of anthracycline drug resistance in leukemia through miR-221, miR-222, miR-26a, and miR-21.
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Relationships between MDMA induced increases in extracellular glucose, glycogenolysis in brain and hyperthermia.
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The design and delivery of a biodegradable poly(lactic-co-glycolic) acid based carrier to the regional lymphatics in rats.
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Preclinical exploration of novel small molecules as anticancer agents in triple-negative and HER2/neu-positive breast cancers.
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Molecular cytotoxic mechanims of fructose and some metabolites in isolated rat hepatocytes.
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Endothelin-1 mediated regulation of extracellular matrix collagens---A role in pathology of primary open angle glaucoma.
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Regulation of cardiac energy metabolism and ischemia reperfusion injury by stress-responsive protein kinases.
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Neurochemical and physiological effects of chronic stress on methamphetamine toxicity.
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The effects of chronic activation of endothelin ETB receptors on blood pressure, venomotor tone, neurohumoral activity, and oxidative stress.
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Pharmacogenetics of the DNA repair and oxidative stress pathways in outcomes of cancer patients.
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Role of glucocorticoid receptor beta in glucocorticoid-induced ocular hypertension.
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Sex hormones and neurovascular protection: Modulation of inflammation and mitochondrial oxidative stress.
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Low-frequency muscle contraction increases microvascular blood volume in normal and insulin resistant states.
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The effects of indirubin derivatives on gene expression and cellular functions in the murine cell line, RAW 264.7.
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Mechanisms of intestinal microsphere uptake and quantitative analysis of organ distribution for applications of oral drug delivery.
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12-lipoxygenase modulates l-type calcium channel-dependent long term potentiation by regulating calcium influx through l-type calcium channels.
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Modulation of the cannabinoid CB1 and CB2 receptor activation in central nervous system disorders.
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Hyperglycemia increases mitochondrial protein expression in the absence of oxidative stress.
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A study on a Chinese herbal medicine preparation to modulate post-injury swelling of the limb: In-vitro and clinical studies.
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Beta-3 integrins enhance TGF-beta-mediated tumor progression in mammary epithelial cells.
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Aurora kinases in solely estrogen-induced oncogenesis: Relation to centrosome amplification and chromosomal instability.
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Single chain variable fragments: Novel applications as selection tools and therapeutic agents in drug discovery.
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Characterization of the rat uridine diphosphate glucuronosyltransferase 1A6 gene: Transcriptional control of inducer- and tissue-specific expression.
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Identification and assessment of the molecular targets of lead and acrylamide using a novel proteomic system coupled with bioinformatic analysis.
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Mediators and moderators of stress management and antidepressant treatment for chronic tension-type headache.
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Identifying and engineering the best oral enzyme therapy for celiac sprue: Two therapeutic options.
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Pharmacogenomic and mechanistic studies on dietary factors in chemoprevention of cancer.
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Elucidation of anti-proliferative and pro-apoptotic signaling induced by the immunomodulatory benzodiazepine Bz-423.
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Modifying paclitaxel induced apoptosis by controlling signal transduction pathways in human leukemia cells.
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The physiological role of the alpha class glutathione S-transferases against oxidative stress and lipid peroxidation.
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The interaction between training mode and caffeine: Cardiovascular responses at rest and during exercise.
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Intrinsic oxidative stress in cancer cells: A biochemical basis for therapeutic selectivity using ROS-generating agents.
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Examining the interactive nature of cytochrome P450 3A4 and P-glycoprotein in intestinal drug metabolism.
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Effect of subchronic and chronic exposure to halogenated aromatic hydrocarbons on cytochrome P450 biomarkers in rats.
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Interindividual variations in drug metabolism: Implications for predicting clinically important drug interactions.
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Metrics evaluating bioavailability and bioequivalence: Principles, and applications in the steady state.
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Bacillus stearothermophilus tryptophanyl-tRNA synthetase: Mutations leading to indolmycin resistance.
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Effets antiarythmiques et proarythmiques du d-sotalol sur les arythmies cardiaques ventriculaires etudies chez le chien (French and English text).
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Mechanisms for platelet hyperactivity and abnormal calcium homeostasis in diabetes mellitus.
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Differential involvement of opioid receptors in regulating the behavioral response to amphetamine in C57BL/6 mice.
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Differential roles for sarcKATP and mitoKATP channels in hypoxia and reoxygenation injury: A study of cell viability and ion channel pharmacology.
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Assessment of apoptosis vs. necrosis in LLC-PK(1) cells following para-aminophenol exposure.
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18-Methoxycoronaridine, morphine and the cholinergic habenulo-interpeduncular pathway.
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The DNA damage induced by, and cellular responses to, the C-1027 family of antitumor antibiotic radiomimetic enediynes.
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An investigation of CYP2E1 phenotype determination utilizing modeling and simulation studies.
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Gene delivery for treating liver fibrosis and improving human islet transplantation.
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Mechanisms of blood-brain and blood-cerebrospinal fluid transport of aluminum in rats.
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The role of poly (ADP-ribose) polymerase-1 inhibitors: Prevention of non glutathione-dependent carbon tetrachloride-induced hepatotoxicity.
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Role of N-acetyltransferase 2 polymorphism in DNA adduct formation and mutagenesis by aromatic and heterocyclic amine carcinogens.
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Cloning and characterization of a novel phospholipase C enzyme, human phospholipase C Eta2.
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Development of a synthetic peptide vaccine and antibody therapeutic for the prevention and treatment of Pseudomonas aeruginosa infection.
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Drug permeability across the buccal mucosa: Role of ionized species activity and development of a predictive model.
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Structural studies on the ligand stimulation of nicotinic acetylcholine receptor alpha9.
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Macrolide and ketolide-based induction of erythromycin resistance methylase type-C in Escherichia coli.
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Protein phosphatase inhibitor-1 as a positive or negative regulator of cardiac contractility.
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New mechanisms of transcriptional regulation of the folate receptor and other genes by steroid receptors.
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From crabs to hamsters: Bioanalytical mass spectrometry for peptidomic analysis and biomarker discovery.
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Gamma-hydroxybutyric acid tolerance development: Pharmacokinetic and pharmacodynamic perspectives.
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Investigating the role of advanced glycation endproducts and the NADPH oxidase in diabetic vascular disease.
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Herpes simplex virus DNA replication and microRNA expression: Molecular pharmacological, computational, and genetic approaches.
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Modulation of cell migration, nuclear localization and cell cycle progression by the L1-CAM cytoplasmic domain: Implications for tumor progression and metastasis.
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Isolation, structure elucidation, and biological characterization of immunostimulants from dietary supplements and natural products.
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Mechanistic studies of the discriminative stimulus properties of dextromethorphan and metabolites.
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Protection by metallothionein from adriamycin induced nephropathy in mice and gene expression profiling during progression of diabetic nephropathy.
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Development of ligand assisted asymmetric synthetic methodology and synthetic progress toward AI-77-B.
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"The Concise Pharmacopeia": An abridged translation with a systematic method for rendering Chinese medical terms.
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Real-time control of electrical stimulation: A novel tool for compound screening and electrophysiologic analysis.
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Population pharmacokinetic/pharmacodynamic modeling: Evaluation of maximum likelihood expectation maximization method in ADAPT 5.
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Surfactant-free biodegradable nanoparticles for antioxidant drug delivery and imaging applications.
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Dynamic pharmacodynamic modeling focused on the protein kinase A signaling pathway.
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Identification and functional characterization of two novel alpha1-adrenergic receptor-interacting proteins.
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Structure and function of a mitochondrial PP2A holoenzyme that regulates neuronal survival.
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Development, validation, and use of a novel [2-carbon-13] uracil breath test to detect dihydropyrimidine dehydrogenase deficiency.
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Microanalyses of amphetamine-induced behaviors: Dose-effect studies in four different rat strains.
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Development and application of ligand-based and structure-based computational drug discovery tools based on frequent subgraph mining of chemical structures.
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Fatty acid transport: Binding to human serum albumin and trafficking in model and biological membranes.
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Spinal and limbic plasticity in the rat during inflammatory nociception and immobilization stress.
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Development of novel unsupervised and supervised informatics methods for drug discovery applications.
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Novel pharmacokinetic/pharmacodynamic investigation for identification of pre-diabetic subjects.
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A study of the localization and trafficking properties of the alpha1D-adrenoceptor using adenoviral vectors in human aortic smooth muscle cells.
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The dose-response effects of melatonin ingestion on sustained exercise, thermoregulation, and associated neurobehavioral assessments.
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Modulation de la P-glycoproteine et evaluation des repercussions electrophysiologiques cardiaques.
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The structure-function relationship of the human intestinal di-peptide transporter,hPepT1.
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Pharmacokinetic/pharmacodynamic modeling of selected receptor/gene mediated effects of corticosteroids.
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Physicochemical characterization of NPC 1161C, an 8-aminoquinoline anti-malarial drug, and its inclusion complexes with cyclodextrins in solution state.
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The anti-arthritic effect and underlying mechanisms of QFGJS, a pharmaceutical preparation from a Chinese herbal formula.
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Signaling mechanisms and neutrophil modulation through the lysophosphatidylcholine receptor, G2A.
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Mass spectrometric analysis of cytoplasmic ribosomal proteins in drug resistant and drug susceptible cell lines.
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EFFECTS OF NICOTINAMIDE ON THE PHARMACODYNAMIC ACTIVITY OF ETHANOL IN INHERENTLY SENSITIVE AND RESISTANT MICE.
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Histone acetylation by ethanol as a mechanism for alcohol dehydrogenase I gene expression in liver.
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Mathematical modeling of signaling pathway dynamics and stochastic gene expression.
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Enhancing rituximab therapy: Analyzing the interaction between rituximab and the human complement pathway.
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The analyses of proteome and phosphoproteome in human prostate tissue using mass spectrometry based proteomic approaches.
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The role of Akt/protein kinase B in postnatal angiogenesis: Insights from Akt knockout mice.
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Effects of low molecular weight glycosaminoglycans in amyloid beta-induced models of Alzheimer's disease.
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The role of inducible nitric oxide synthase (iNOS) on cardiovascular function in rats with streptozotocin-induced diabetes.
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The direct and indirect effects of herbal products on common drug metabolizing enzymes and drug transporters.
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Prevention of beta-amyloid neurotoxicity by microtubule-stabilizing drugs: The calcium(2+) connection.
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Gemini cationic surfactant-based delivery systems for non-invasive cutaneous gene therapy.
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Adolescent 3,4-methylenedioxymethamphetamine (MDMA or 'ecstasy') exposure in rats: Behavioral, neurochemical, and pharmocokinetic activity.
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Understanding the decision making and use of medicines by elderly patients: Impact of pharmaceutical care.
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Therapeutic antibody formulation: Phase behavior, opalescence, viscosity, physical and chemical stability.
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The role of endocannabinoid receptor activity in young and aged rats with high-fat feeding.
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Cellular Heterogeneity as a Mechanism of Resistance to EGFR Inhibition in Glioblastoma.
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An implantable biomedical device and nanoparticles for cancer drug release and hyperthermia.
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Structural and functional implications of DNA delivery vehicle formulation design for targeted cancer gene therapy.
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Novel Traditional Chinese Medicine-Platinum Compound that Bypasses Mitotic DNA Damage Checkpoints in Cancer Cells.
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Computational Modeling of Anti-aggregation Effect of Non-steroidal Anti-inflammatory Drugs in Alzheimer's Amyloidogenesis.
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Polymeric nanoparticles for the intracellular delivery of paclitaxel in lung and breast cancer.
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Prenatal LPS exposure alters the development of the nigrostriatal pathway by disrupting neurotrophic factors.
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Neurokinin 1 receptors and their role in opioid-induced hyperalgesia, antinociceptive tolerance and reward.
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Mechanisms of anti-proliferative effects of glyceollins in estrogen-dependent and -independent tumor cells.
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Oxidative stress and nitric oxide production in an in vitro human endothelial cell model.
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Inhibition of tumor progression by inhibition of ganglioside biosynthesis: Models and mechanisms.
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Discerning the role of LMO4 as a global modulator of G2/M cell cycle progression and centrosome cycle in breast cancer cells.
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Bone morphogenetic protein 2 (BMP2) regulates follicle-stimulating hormone beta subunit (Fshb) expression in gonadotrope cells.
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Infrared atmospheric pressure matrix-assisted laser desorption/ionization ion trap mass spectrometry.
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Analysis of the bioactivity, metabolism, and pharmacokinetics of anthocyanins in humans.
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Enhancing the pharmaceutical behavior of poorly soluble drugs through the formation of cocrystals and mesophases.
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A calcium dependent model of heart failure: Characterization and mechanisms towards prevention.
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In vitro and in vivo pharmacologic evaluation of novel lysophospholipid analogs as anticancer agents.
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Big Data in Systems Medicine and Systems Pharmacology: From Correlations to Clinical Predictions.
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The serotonin 5-HT(7) receptor: Circadian rhythm regulation and mechanism of antidepressant action.
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Modulation de l'activite du noeud sinusal par les peptides natriuretiques (French text).
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Postnatal development of nigral dopamine containing neurons: Electrophysiological studies in vitro.
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Structure, gating and modulation of hyperpolarization-activated HCN pacemaker channels.
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Effects of morphine, d-amphetamine, and food deprivation on temporally organized behavior.
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A test of the serotonin hypothesis of nonphotic phase shifting of the Syrian hamster circadian system.
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Neuroprotective effects of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) ligands against oxidative stress.
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Investigation of the role of transporters in the absorption and secretion of drugs across the blood-brain barrier.
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The role of dopamine receptor signaling in the rat nucleus accumbens in cocaine-induced reinstatement.
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Dopamine and ethanol induced trafficking of viral mediatedeGFP tagged dopamine D1 receptors in parasagittal explants.
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Determinant of reinforcing efficacy of phenyltropanes: Onset of dopamine transporter occupancy.
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Genetic variation in the human dopamine transporter gene and its role in attention deficit hyperactivity disorder.
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Inhibition of intestinal tumorigenesis in ApcMin mouse model by (-)-epigallocatechin-3-gallate, a major catechin in green tea.
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Modulation of DNA methylation by catechol-O-methyltransferase and catechol-containing dietary polyphenols.
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Lipid peroxidation-derived endogenous DNA- and GSH-adducts as biomarkers of oxidative stress.
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Pro-oxidative activities of (-)-epigallocatechin-3-gallate: Auto-oxidation and induction of oxidative stress.
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Alterations in indices of oxidative stress and diabetes in type I diabetic rats on a low-carbohydrate diet and pycnogenol.
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PPAR-gamma: A multifaceted transcription factor important in diabetes, cardiovascular disease, and cancer.
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Mechanisms of induction of neuroadaptations following repeated, intermittent amphetamine.
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The ubiquitin ligase RAD18 is implicated in mutagenic translesion synthesis of DNA damage in human cells.
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Anti-estrogen therapy and breast cancer: Molecular mechanisms of efficacy and resistance.
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Neuroprotective effect of a mixture of conjugated linoleic acid isomers on neuronal cell death.
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CD4(+) lymphocyte regulation of vascular and cardiac extracellular matrix structure and function.
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Pharmacogenetic studies of membrane transporters relevant to anti-cancer drug therapy.
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The role of efflux transporters in the pharmacokinetics and pharmacodynamics of anti-cancer drugs.
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Xenobiotic regulation of phase I and phase II metabolism enzymes: Beyond the Ah receptor paradigm.
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Development and validation of in vitro screening procedure for identifying herbals possessing sulfonylurea-like activity.
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The anti-adipogenic activity of Banaba extract, tannic acid and penta-O-galloyl-D-glucose.
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Studies of the effects of pancreatic beta cell antioxidant transgenes on experimental models of diabetes.
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Pharmacokinetics and bioavailability of selegiline in the dog using an enzymatic assay.
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Bioavailability of the tea flavonoids epicatechin and epicatechin gallate: Role of membrane transport and metabolism.
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Alterations in the permeability of cimetidine by dietary flavonoids using an in vitro transport model, Caco-2 cells.
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Statistical design and analysis of high throughput screening data using pooling experiments and data mining techniques.
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Ultrasound-mediated transdermal insulin delivery and glucose measurement using the cymbal array.
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Analysis of dihydrofolate reductase variations in relation to antifolate resistance in Plasmodium vivax.
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Studies on the molecular basis of substrate specificity and inhibition of the GCN5/PCAF histone acetyltransferases.
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Induction of angiogenesis by arsenic: Mechanisms for arsenic-induced vascular disease.
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Mechanisms of immunosuppression following administration of opioids and induction of abstinence.
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Antioxidative, anticancer and antiinflammatory properties of isoflavones from kudzu (Pueraria lobata) root.
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Influences of dietary soy isoflavones on metabolism, stress/pain response and neuronal apoptosis in rats.
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Effects of aging and exercise training on endothelium-dependent vasodilation of skeletal muscle arterioles.
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1,25-dihydroxyvitamin D3 regulation of osteocalcin mRNA stability: A search for cis- and trans-acting determinants.
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Substrate specificity and catalytic mechanism of NADPH-dependent alkenal/one oxidoreductase.
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Molecular mobility, physical stability, and transformation kinetics of amorphous and hydrated pharmaceutical solids.
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Contributions of the GABA(A) receptor alpha(1) subunit to the structure and dynamics of the neurotransmitter binding pocket.
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Agonist-induced conformational changes in TRH receptor: A disulfide cross-linking and molecular modeling approach.
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Mitochondrial glutathione and calcium regulation in cardiac myocytes: From oxidative stress to cardiomyopathy.
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Using the electronic medical record to predict the pharmacological management of acute myocardial infarction.
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Variability in CYP3A expression and metabolism: Influence of genetics and probe substrate selection.
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Cytochrome P4501A1: Is it a suitable biomarker of exposure to dioxin-like persistent organic pollutants and time to pregnancy?
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Converting an oncogenic protein into an apoptotic factor: Targeting Bcr-Abl to the mitochondria.
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Olfactory Uptake of Inhaled Nanoparticle Aerosols -- an Examination of Uptake, Transport, and Fate in the Upper Respiratory Tracts of Mice.
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