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SECTION I. MOLECULAR PRINCIPLES -- Chapter 1 Molecular Biology Basics for the Pathologist, Ilka Warshawsky -- Chapter 2 Quality Assurance of Molecular Assays, Wayne W. Grody -- SECTION II. MOLECULAR TOOLS AND TECHNIQUES -- Chapter 3 Overview of Molecular Diagnostic Techniques and Instrumentation, Daniel H. Farkas and Carol A. Holland -- Chapter 4 Conventional and Real Time Polymerase Chain Reaction (PCR), Aaron Bossler and Vivianna Van Deerlin -- Chapter 5 Loss of Heterozygosity, Jennifer L. Hunt -- Chapter 6 Direct Genome Sequencing in Diagnostic Pathology, Gurunathan Murugesan and Gary W. Procop -- Chapter 7 Array-Based Comparative Genomic Hybridization in the Analysis of Genomic Alterations in Human Disease, Marek Skacel, Ana Ambu Siva, and Raymond R. Tubbs -- Chapter 8 Expression Arrays: Discovery and Validation, Neal Poulin and Torsten O. Nielsen -- Chapter 9 Epigenetics: DNA Hypermethylation in Cancer, Bin Yang -- Chapter 10 Tissue Microarrays, Ziad Peerwani -- Chapter 11 Fluorescence in Situ Hybridization, James R. Cook -- Chapter 12 Bright Field in Situ Hybridization, Ricardo V. Lloyd, Xiang Qian, and Long Jin -- Chapter 13 Immunoglobulin and T-Cell Receptor Gene Rearrangement, Margaret L. Gulley -- Chapter 14 Monitoring of Minimal Residual Hematologic Disease, Cuihong Wei, Jeffrey H. Lipton, and Suzanne Kamel-Reid -- Chapter 15 Molecular Detection of Circulating Tumor Cells, Karen L. Kaul -- Chapter 16 Intraoperative Molecular Staging Using Real-Time PCR, Tony E. Godfrey -- SECTION III. DIAGNOSTIC MOLECULAR PATHOLOGY APPLICATIONS -- Chapter 17, Molecular Cytopathology, Karen S. Gustafson and Douglas P. Clark -- Chapter 18 Molecular Diagnosis of Infectious Agents in Tissue, Randall T. Hayden and Gary W. Procop -- Chapter 19 Molecular Neuropathology, Richard Prayson -- Chapter 20 Molecular Pathology of the Cardiovascular System, Carmela D. Tan and E. Rene Rodriguez -- Chapter 21 Molecular Pulmonary Pathology, Samuel Yousem and Sanja Dacic -- Chapter 22 Molecular Dermatopathology, Alexander J.F. Lazar, Jason W. Nash, and Abdul Hafeez Diwan -- Chapter 23 Molecular Gastrointestinal, Liver, and Pancreatic Pathology, Rish K. Pai, Rebecca Wilcox, and John Hart -- Chapter 24 Molecular Endocrine Pathology, Jennifer L. Hunt -- Chapter 25 Molecular Hematopathology, James R. Cook -- Chapter 26 Molecular Pathology of Bone and Soft Tissue Tumors, Brian P. Rubin, Alexander J.F. Lazar, and Andre Oliveira -- Chapter 27 Molecular Pathology of Breast Cancer, David G. Hicks -- Chapter 28 Molecular Genitourinary Pathology, Donna E. Hansel, Cristina Magi-Galluzzi, and Ming Zhou -- Chapter 29 Molecular Gynecologic Pathology, Monica Prasad Hayes, Edyta C. Pirog, and Lora Hedrick Ellenson -- Chapter 30 Pediatric Molecular Pathology, Robin LeGallo. |
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Section II: Molecular tools and techniques -- Overview of molecular diagnostic techniques and instrumentation / Daniel H. Farkas and Carol A. Holland -- Conventional and real-time polymerase chain reaction/ Aaron Bossler and Vivianna Van Deerlin -- Loss of heterozygosity / Jennifer L. Hunt -- Direct genome sequencing in diagnostic pathology/ Gurunathan Murugesan and Gary W. Procop -- Array-based comparative genomic hybridization in the analysis of genomic alterations in human disease / Marek Skacel, Anna Ambu Siva, and Raymond R. Tubbs -- Expression arrays: discovery and validation/ Neal M. Poulin and Torsten O. Nielsen -- Epigenetics: DNA hypermethylation in cancer / Bin Yang -- Tissue microarrays / Ziad Peerwani -- Fluorescence in situ hybridization / James R. Cook -- Bright-field in situ hybridization/ Ricardo V. Lloyd, Xiang Qian, and Long Jin -- Immunoglobulin and T-cell receptor gene rearrangement / Margaret L. Gulley -- Monitoring of minimal residual hematologic disease/ Cuihong Wei, Jeffrey H. Lipton, and Suzanne Kamel-Reid -- Molecular detection of circulating tumor cells / Karen L. Kaul -- Intraoperative molecular staging using real-time polymerase chain reaction / Tony E. Godfrey -- |
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Section III: Diagnostic molecular pathology applications -- Molecular cytopathology / Karen S. Gustafson and Douglas P. Clark -- Molecular diagnosis of infectious agents in tissue / Randall T. Hayden and Gary W. Procop -- Molecular neuropathology/ Richard Prayson -- Molecular pathology of the cardiovascular system / Carmela D. Tan and E. Rene Rodriguez -- Molecular pulmonary pathology / Samuel Yousem and Sanja Dacic -- Molecular dermatopathology/ Alexander J.F. Lazar, Jason W. Nash, and Abdul Hafeez Diwan -- Molecular gastrointestinal, liver, and pancreatic pathology / Rish K. Pai, Rebecca Wilcox, and John Hart -- Molecular endocrine pathology / Jennifer L. Hunt -- Molecular hematopathology/ James R. Cook -- Molecular pathology of bone and soft tissue tumors / Brian P. Rubin, Alexander J.F. Lazar, and Andre M. Oliveira -- Molecular pathology of breast cancer / David G. Hicks -- Molecular genitourinary pathology/ Donna E. Hansel, Cristina Magi-Galluzzi, and Ming Zhou -- Molecular gynecologic pathology / Monica Prasad Hayes, Edyta C. Pirog, and Lora Hedrick Ellenson -- Pediatric molecular pathology / Robin LeGallo. |