東華大學圖書館 |

語系: 繁體中文

說明(常見問題)

回圖書館首頁

手機版館藏查詢

登入

回首頁 到查詢結果 [ subject:"Macroecology." ]

切換: 標籤 | MARC模式 | ISBD

A Study of Anticancer Agents Derived...

Almosnid, Nadin Marwan.

FindBook

Google Book

Amazon

博客來

A Study of Anticancer Agents Derived from Plants Utilized in Traditional Chinese Medicine (TCM).

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	A Study of Anticancer Agents Derived from Plants Utilized in Traditional Chinese Medicine (TCM)./
作者:	Almosnid, Nadin Marwan.
出版者:	Ann Arbor : ProQuest Dissertations & Theses, : 2018,
面頁冊數:	111 p.
附註:	Source: Dissertation Abstracts International, Volume: 79-09(E), Section: B.
Contained By:	Dissertation Abstracts International79-09B(E).
標題:	Molecular biology. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10785190
ISBN:	9780355931129

A Study of Anticancer Agents Derived from Plants Utilized in Traditional Chinese Medicine (TCM).
Almosnid, Nadin Marwan.

A Study of Anticancer Agents Derived from Plants Utilized in Traditional Chinese Medicine (TCM). - Ann Arbor : ProQuest Dissertations & Theses, 2018 - 111 p.

Source: Dissertation Abstracts International, Volume: 79-09(E), Section: B.

Thesis (Ph.D.)--Middle Tennessee State University, 2018.

Cancer is caused by abnormal cellular growth. It has the ability to invade any tissue of the body and can spread from the area or origin throughout the body. Chemotherapy has been used for decades to treat cancer. However, the effectiveness of chemotherapeutic drugs are severely limited by drug resistance which can develop over time and the inherent severe toxic effects of chemotherapeutic drugs to normal tissue. Due to these limitations of cancer therapy, there is an urgent need to develop new anticancer drugs. A revitalization of interest in drug discovery research on natural products derived from plants has occurred in recent years, and the biological activity of these products has attracted the attention of chemists, biochemists, biologists, and microbiologists. As a part of traditional culture in China, medicinal plants from traditional Chinese medicine (TCM) have been used for thousands of years to treat and prevent diseases. Herbal medicine used in TCM plays an integral role in primary health care in East Asia, as it has been used for many generations by the Chinese community. Our findings suggest that extracts from Yao Ethnomedicine and compounds cis- and trans-suffruticosol D isolated from the seeds of Paeonia suffruticosa have promising chemotherapeutic potential for treating cancer. The most promising Yao Ethnomedicinal plants were the extracts from Extracts from Bidens biternata, Wedelia calendulacea and Stephania longa because of their cytotoxicity and selectivity. Our findings suggest also that both cis- and trans-suffruticosol D have promising chemotherapeutic potential for treating cancer. The experimental data suggested that both cis- and trans-suffruticosol D inhibited cancer cells through apoptosis induction.

ISBN: 9780355931129Subjects--Topical Terms:

517296
Molecular biology.

A Study of Anticancer Agents Derived from Plants Utilized in Traditional Chinese Medicine (TCM).
LDR:02765nmm a2200313 4500 001 2204415
005 20190716100705.5
008 201008s2018 ||||||||||||||||| ||eng d
020 $a 9780355931129
035 $a (MiAaPQ)AAI10785190
035 $a (MiAaPQ)mtsu:10943
035 $a AAI10785190
040 $a MiAaPQ $c MiAaPQ
100 1 $a Almosnid, Nadin Marwan. $3 3431271
245 1 2 $a A Study of Anticancer Agents Derived from Plants Utilized in Traditional Chinese Medicine (TCM).
260 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2018
300 $a 111 p.
500 $a Source: Dissertation Abstracts International, Volume: 79-09(E), Section: B.
500 $a Advisers: Elliot Altman; Ying Gao.
502 $a Thesis (Ph.D.)--Middle Tennessee State University, 2018.
520 $a Cancer is caused by abnormal cellular growth. It has the ability to invade any tissue of the body and can spread from the area or origin throughout the body. Chemotherapy has been used for decades to treat cancer. However, the effectiveness of chemotherapeutic drugs are severely limited by drug resistance which can develop over time and the inherent severe toxic effects of chemotherapeutic drugs to normal tissue. Due to these limitations of cancer therapy, there is an urgent need to develop new anticancer drugs. A revitalization of interest in drug discovery research on natural products derived from plants has occurred in recent years, and the biological activity of these products has attracted the attention of chemists, biochemists, biologists, and microbiologists. As a part of traditional culture in China, medicinal plants from traditional Chinese medicine (TCM) have been used for thousands of years to treat and prevent diseases. Herbal medicine used in TCM plays an integral role in primary health care in East Asia, as it has been used for many generations by the Chinese community. Our findings suggest that extracts from Yao Ethnomedicine and compounds cis- and trans-suffruticosol D isolated from the seeds of Paeonia suffruticosa have promising chemotherapeutic potential for treating cancer. The most promising Yao Ethnomedicinal plants were the extracts from Extracts from Bidens biternata, Wedelia calendulacea and Stephania longa because of their cytotoxicity and selectivity. Our findings suggest also that both cis- and trans-suffruticosol D have promising chemotherapeutic potential for treating cancer. The experimental data suggested that both cis- and trans-suffruticosol D inhibited cancer cells through apoptosis induction.
590 $a School code: 0170.
650 4 $a Molecular biology. $3 517296
650 4 $a Macroecology. $3 3188544
650 4 $a Pharmaceutical sciences. $3 3173021
690 $a 0307
690 $a 0420
690 $a 0572
710 2 $a Middle Tennessee State University. $b Biology. $3 3181221
773 0 $t Dissertation Abstracts International $g 79-09B(E).
790 $a 0170
791 $a Ph.D.
792 $a 2018
793 $a English
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10785190