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Immune checkpoint inhibitors in cancer
Ito, Fumito,

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  • Immune checkpoint inhibitors in cancer
  • 紀錄類型: 書目-電子資源 : Monograph/item
    正題名/作者: Immune checkpoint inhibitors in cancer/ Fumito Ito, Marc S. Ernstoff.
    其他作者: Ito, Fumito,
    出版者: St. Louis, Missouri :Elsevier, : 2019.,
    面頁冊數: 1 online resource.
    內容註: Intro; Title page; Table of Contents; Copyright; Dedication; List of Contributors; Preface; Chapter 1. Immune Checkpoint Inhibitors: Mechanisms and Emerging Therapeutic Opportunities; Introduction; Immune Checkpoint Inhibition: Molecules and Mechanisms; Regulation of the Immune Checkpoint Molecules on Activated T Cells; Regulation of the Expression of Immune Checkpoint Ligands; Factors Affecting the Anti tumor Effectiveness of Immune Checkpoint Inhibitors; Targeting the Tumor Microenvironment to Enhance the Therapeutic Effectiveness of Immune Checkpoint Inhibitors; Conclusions
    內容註: Chapter 2. Immune Checkpoints: Melanoma and Other Skin Cancers melanoma; Background; Ipilimumab (Anti-CTLA-4 Antibody); PD-1 Blockade; Special Considerations With the Use of Immune Checkpoint Inhibitor; Duration of Treatment; The Use of Immune Checkpoint Inhibitors in Specific Populations; Immune Checkpoint Inhibitors for Adjuvant Therapy; Biomarkers for Immune Checkpoint Inhibitor Response; Mechanisms of Resistance; Novel Immune Checkpoint Inhibitors and Combinationsin Development; Conclusion; Merkel Cell Carcinoma; Immunotherapy of Merkel Cell Carcinoma; Conclusion; Conclusion
    內容註: Chapter 3. The Current Status of Immunotherapy in Thoracic Malignancies Introduction; Immune Checkpoint Inhibition; Non-Small-Cell Lung Cancer; Biomarkers of Response or Resistance to Immune Checkpoint Inhibitor Therapy; Future Directions; Combination Therapy With Other Immunotherapy; Non-Small-Cell Lung Cancer; Individualized Tumor Neoantigen-Based Vaccines; Conclusion; Chapter 4. Immune Checkpoint Inhibitors in Gastrointestinal Malignancies; Introduction; Gastroesophageal Cancer; Hepatocellular Carcinoma; Cholangiocarcinoma; Pancreatic Adenocarcinoma; Colorectal Cancer; Anal Cancer
    內容註: Patient Selection for Immunotherapy and Biomarker Development summary/Conclusion; Chapter 5. Cancers of the Head and Neck; Introduction; Molecular Biology of Head and Neck Cancers; Immune Escape in Head and Neck Cancer; Squamous Cell Carcinoma of Head and Neck; Nasopharyngeal Carcinoma; Salivary Glands Cancer; Conclusion; Chapter 6. Urologic Malignancies; Kidney Cancer; Background: Prior Immunotherapies in Renal Cell Carcinoma; Single-Agent Immune Checkpoint Inhibitors; Combination or ICI-VEGFi; Bladder Cancer; PD-L1-Targeted Agents; PD-L1-Targeted Agents; CTLA-4-Targeted Agents; Other Agents
    內容註: Prostate Cancer Chapter 7. Gynecologic Malignancies; Introduction; Ovarian Cancer; Endometrial Cancer; Cervical Cancer; Future Directions; Chapter 8. Breast Cancer; Introduction; Mutational Burden/Tumor-Associated Antigens in BreastCancer; Significance of Tumor-Infiltrating Lymphocytes in Breast Cancer; Programmed Death-Ligand 1 [PD-L1] PD-L1 Expression in Breast Cancer; PD-L1 and PD-1 Inhibitor Studies in Metastatic Breast Cancer; Neoadjuvant Breast Studies; Conclusion; Chapter 9. Hematologic Malignancies; Introduction; Immune Checkpoint Pathway Dysregulation in Hematologic Malignancies
    標題: Cancer - Immunological aspects. -
    電子資源: https://www.sciencedirect.com/science/book/9780323549486
    ISBN: 9780323549509 (electronic bk.)
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