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Predictive approaches in drug discov...

Williams, J. Andrew.

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Predictive approaches in drug discovery and development = biomarkers and in vitro/in vivo correlations /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Predictive approaches in drug discovery and development/ edited by J. Andrew Williams ... [et al.].
其他題名:	biomarkers and in vitro/in vivo correlations /
其他作者:	Williams, J. Andrew.
出版者:	Hoboken, N.J. :Wiley, : c2012 .,
面頁冊數:	xvii, 387 p. :ill. ;25 cm.
內容註:	The importance of biomarkers in translational medicine / Joseph Fleishaker -- Fit for purpose validation of biochemical assays : challenges and solutions / Gabriella Szekely-Klepser and Scott Fountain -- Transcriptional profiling in biomarker discovery / Michael E. Burczynski ... [et al.] -- Proteomic biomarker approaches in drug discovery and development / Ruth A. Vanbogelen, Jeffrey D. Thomas, and Diane Alessi -- Application of metabolomics to pharmaceutical research and development / Qiuwei Xu and William H. Schaefer -- Vascular biomarkers and imaging studies / Karin Potthoff, Ulrike Fiedler, and Joachim Drevs -- Cardiovascular biomarkers as examples of success and failure in predicting safety in humans / Simon Authier ... [et al.] -- Use of molecular imaging for receptor occupancy decision making in drug development / R. Paul Maguire -- Biosensors for clinical biomarkers / Sara Tombelli and Marco Mascini -- US regulatory perspective on biomarker development / Rajnikath Madabushi, Lawrence Lesko, and Janet Woodcock -- EU regulatory perspective on biomarkers / Ian Hudson -- Use of biomarkers in drug development : Japanese perspectives / Yoshiaki Uyama ... [et al.] -- In vitro-in vivo correlations of hepatic drug clearance / R. Scott Obach -- The potential of in silico and in vitro approaches to predict in vivo drug-drug interactions and ADMET/TOX properties / Kenneth Bachmann and Sean Ekins -- In vitro-in vivo correlations in drug discovery and development : concepts and applications in toxicology / Rex Denton, Kimberly Brannen, and Buce D. Car -- Assessing the potential for induction of cytochrome P450 enzymes and predicting the in vivo response / Jiunn H. Lin.
標題:	Biochemical markers. -
電子資源:	http://onlinelibrary.wiley.com/book/10.1002/9781118230275
ISBN:	9781118230275 (ebk.)

Predictive approaches in drug discovery and development = biomarkers and in vitro/in vivo correlations /
Predictive approaches in drug discovery and developmentbiomarkers and in vitro/in vivo correlations /[electronic resource] :edited by J. Andrew Williams ... [et al.]. - Hoboken, N.J. :Wiley,c2012 . - xvii, 387 p. :ill. ;25 cm. - Wiley series on technologies for the pharmaceutical industry. - Wiley series on technologies for the pharmaceutical industry..

Includes bibliographical references and index.

The importance of biomarkers in translational medicine / Joseph Fleishaker -- Fit for purpose validation of biochemical assays : challenges and solutions / Gabriella Szekely-Klepser and Scott Fountain -- Transcriptional profiling in biomarker discovery / Michael E. Burczynski ... [et al.] -- Proteomic biomarker approaches in drug discovery and development / Ruth A. Vanbogelen, Jeffrey D. Thomas, and Diane Alessi -- Application of metabolomics to pharmaceutical research and development / Qiuwei Xu and William H. Schaefer -- Vascular biomarkers and imaging studies / Karin Potthoff, Ulrike Fiedler, and Joachim Drevs -- Cardiovascular biomarkers as examples of success and failure in predicting safety in humans / Simon Authier ... [et al.] -- Use of molecular imaging for receptor occupancy decision making in drug development / R. Paul Maguire -- Biosensors for clinical biomarkers / Sara Tombelli and Marco Mascini -- US regulatory perspective on biomarker development / Rajnikath Madabushi, Lawrence Lesko, and Janet Woodcock -- EU regulatory perspective on biomarkers / Ian Hudson -- Use of biomarkers in drug development : Japanese perspectives / Yoshiaki Uyama ... [et al.] -- In vitro-in vivo correlations of hepatic drug clearance / R. Scott Obach -- The potential of in silico and in vitro approaches to predict in vivo drug-drug interactions and ADMET/TOX properties / Kenneth Bachmann and Sean Ekins -- In vitro-in vivo correlations in drug discovery and development : concepts and applications in toxicology / Rex Denton, Kimberly Brannen, and Buce D. Car -- Assessing the potential for induction of cytochrome P450 enzymes and predicting the in vivo response / Jiunn H. Lin.

ISBN: 9781118230275 (ebk.)

LCCN: 2011040419Subjects--Topical Terms:

587592
Biochemical markers.

LC Class. No.: R853.B54 / P74 2012

Dewey Class. No.: 615.19

National Library of Medicine Call No.: QV 744

Predictive approaches in drug discovery and development = biomarkers and in vitro/in vivo correlations /
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