東華大學圖書館 |

語系: 繁體中文

說明(常見問題)

回圖書館首頁

手機版館藏查詢

登入

回首頁 到查詢結果 [ subject:"Chemogenomics." ]

切換: 標籤 | MARC模式 | ISBD

Chemical epigenetics

Mai, Antonello.

FindBook

Google Book

Amazon

博客來

Chemical epigenetics

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Chemical epigenetics/ edited by Antonello Mai.
其他作者:	Mai, Antonello.
出版者:	Cham :Springer International Publishing : : 2020.,
面頁冊數:	ix, 567 p. :ill., digital ;24 cm.
內容註:	Targeting the Zinc-Dependent Histone Deacetylases (HDACs) for Drug Discovery -- Hydroxamic Acid-Containing Peptides in the Study of Histone Deacetylases -- Sirtuin Inhibitors and Activators -- Histone Acetyltransferase Enzymes: From Biological Implications to Most Relevant Inhibitors -- Lysine Methyltransferases and Their Inhibitors -- PRMT Inhibitors -- Lysine-Specific Histone Demethylases 1/2 (LSD1/2) and Their Inhibitors -- Inhibitors of JmjC-Containing Histone Demethylases -- Chemical Compounds Targeting DNA Methylation and Hydroxymethylation -- Applied Biophysics for Bromodomain Drug Discovery -- Methyl-Readers and Inhibitors -- Altered Long Non-coding RNA Expression in Cancer: Potential Biomarkers and Therapeutic Targets? - Acetylation and Methylation in Asthma, COPD, and Lung Cancer -- Structure-Based Design ofEpigenetic Inhibitors -- Experimental Methodologies for Detection and Mapping of Epigenetic DNA Marks -- Advanced Assays in Epigenetics.
Contained By:	Springer eBooks
標題:	Chemogenomics. -
電子資源:	https://doi.org/10.1007/978-3-030-42982-9
ISBN:	9783030429829

Chemical epigenetics
Chemical epigenetics[electronic resource] /edited by Antonello Mai. - Cham :Springer International Publishing :2020. - ix, 567 p. :ill., digital ;24 cm. - Topics in medicinal chemistry,331862-2461 ;. - Topics in medicinal chemistry ;33..

Targeting the Zinc-Dependent Histone Deacetylases (HDACs) for Drug Discovery -- Hydroxamic Acid-Containing Peptides in the Study of Histone Deacetylases -- Sirtuin Inhibitors and Activators -- Histone Acetyltransferase Enzymes: From Biological Implications to Most Relevant Inhibitors -- Lysine Methyltransferases and Their Inhibitors -- PRMT Inhibitors -- Lysine-Specific Histone Demethylases 1/2 (LSD1/2) and Their Inhibitors -- Inhibitors of JmjC-Containing Histone Demethylases -- Chemical Compounds Targeting DNA Methylation and Hydroxymethylation -- Applied Biophysics for Bromodomain Drug Discovery -- Methyl-Readers and Inhibitors -- Altered Long Non-coding RNA Expression in Cancer: Potential Biomarkers and Therapeutic Targets? - Acetylation and Methylation in Asthma, COPD, and Lung Cancer -- Structure-Based Design ofEpigenetic Inhibitors -- Experimental Methodologies for Detection and Mapping of Epigenetic DNA Marks -- Advanced Assays in Epigenetics.

This book presents an authoritative review of the most significant findings about all the epigenetic targets (writers, readers, and erasers) and their implication in physiology and pathology. The book also covers the design, synthesis and biological validation of epigenetic chemical modulators, which can be useful as novel chemotherapeutic agents. Particular attention is given to the chemical mechanisms of action of these molecules and to the drug discovery prose which allows their identification. This book will appeal to students who want to know the extensive progresses made by epigenetics (targets and modulators) in the last years from the beginning, and to specialized scientists who need an instrument to quickly search and check historical and/or updated notices about epigenetics.

ISBN: 9783030429829

Standard No.: 10.1007/978-3-030-42982-9doiSubjects--Topical Terms:

3231947
Chemogenomics.

LC Class. No.: QH438.4.C45 / C446 2020

Dewey Class. No.: 615.7

Chemical epigenetics
LDR:02777nmm a2200337 a 4500 001 2216820
003 DE-He213
005 20200729110046.0
006 m d
007 cr nn 008maaau
008 201120s2020 sz s 0 eng d
020 $a 9783030429829 $q (electronic bk.)
020 $a 9783030429812 $q (paper)
024 7 $a 10.1007/978-3-030-42982-9 $2 doi
035 $a 978-3-030-42982-9
040 $a GP $c GP
041 0 $a eng
050 4 $a QH438.4.C45 $b C446 2020
072 7 $a PSB $2 bicssc
072 7 $a SCI013020 $2 bisacsh
072 7 $a PSB $2 thema
082 0 4 $a 615.7 $2 23
090 $a QH438.4.C45 $b C517 2020
245 0 0 $a Chemical epigenetics $h [electronic resource] / $c edited by Antonello Mai.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2020.
300 $a ix, 567 p. : $b ill., digital ; $c 24 cm.
490 1 $a Topics in medicinal chemistry, $x 1862-2461 ; $v 33
505 0 $a Targeting the Zinc-Dependent Histone Deacetylases (HDACs) for Drug Discovery -- Hydroxamic Acid-Containing Peptides in the Study of Histone Deacetylases -- Sirtuin Inhibitors and Activators -- Histone Acetyltransferase Enzymes: From Biological Implications to Most Relevant Inhibitors -- Lysine Methyltransferases and Their Inhibitors -- PRMT Inhibitors -- Lysine-Specific Histone Demethylases 1/2 (LSD1/2) and Their Inhibitors -- Inhibitors of JmjC-Containing Histone Demethylases -- Chemical Compounds Targeting DNA Methylation and Hydroxymethylation -- Applied Biophysics for Bromodomain Drug Discovery -- Methyl-Readers and Inhibitors -- Altered Long Non-coding RNA Expression in Cancer: Potential Biomarkers and Therapeutic Targets? - Acetylation and Methylation in Asthma, COPD, and Lung Cancer -- Structure-Based Design ofEpigenetic Inhibitors -- Experimental Methodologies for Detection and Mapping of Epigenetic DNA Marks -- Advanced Assays in Epigenetics.
520 $a This book presents an authoritative review of the most significant findings about all the epigenetic targets (writers, readers, and erasers) and their implication in physiology and pathology. The book also covers the design, synthesis and biological validation of epigenetic chemical modulators, which can be useful as novel chemotherapeutic agents. Particular attention is given to the chemical mechanisms of action of these molecules and to the drug discovery prose which allows their identification. This book will appeal to students who want to know the extensive progresses made by epigenetics (targets and modulators) in the last years from the beginning, and to specialized scientists who need an instrument to quickly search and check historical and/or updated notices about epigenetics.
650 0 $a Chemogenomics. $3 3231947
650 0 $a Epigenetics. $3 1568224
650 1 4 $a Medicinal Chemistry. $3 892420
650 2 4 $a Genetics and Genomics. $3 3385208
650 2 4 $a Enzymology. $3 540241
650 2 4 $a Industrial Chemistry/Chemical Engineering. $3 890826
700 1 $a Mai, Antonello. $3 3449532
710 2 $a SpringerLink (Online service) $3 836513
773 0 $t Springer eBooks
830 0 $a Topics in medicinal chemistry ; $v 33. $3 3449533
856 4 0 $u https://doi.org/10.1007/978-3-030-42982-9
950 $a Chemistry and Materials Science (Springer-11644)