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[ subject:"Chemistry, Biochemistry." ]
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DNA-directed self-assembly of nanopa...
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Arizona State University.
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DNA-directed self-assembly of nanoparticle arrays.
紀錄類型:
書目-語言資料,印刷品 : Monograph/item
正題名/作者:
DNA-directed self-assembly of nanoparticle arrays./
作者:
Sharma, Jaswinder Kumar.
面頁冊數:
215 p.
附註:
Source: Dissertation Abstracts International, Volume: 70-04, Section: B, page: 2290.
Contained By:
Dissertation Abstracts International70-04B.
標題:
Chemistry, Biochemistry. -
電子資源:
http://pqdd.sinica.edu.tw/twdaoeng/servlet/advanced?query=3353682
ISBN:
9781109102727
DNA-directed self-assembly of nanoparticle arrays.
Sharma, Jaswinder Kumar.
DNA-directed self-assembly of nanoparticle arrays.
- 215 p.
Source: Dissertation Abstracts International, Volume: 70-04, Section: B, page: 2290.
Thesis (Ph.D.)--Arizona State University, 2009.
Recently, deoxyribonucleic acid (DNA) has emerged as a powerful tool for the construction of sophisticated structures at the nanometer scale, which can be applied for organization of materials like nanoparticles, proteins and antibodies at the nanoscale. Stability at physiological conditions, availability of various chemical modifications, and ease of synthesis have made DNA a material of choice for nanoconstructions comparable to other biomaterials at the nanometer scale.
ISBN: 9781109102727Subjects--Topical Terms:
1017722
Chemistry, Biochemistry.
DNA-directed self-assembly of nanoparticle arrays.
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Recently, deoxyribonucleic acid (DNA) has emerged as a powerful tool for the construction of sophisticated structures at the nanometer scale, which can be applied for organization of materials like nanoparticles, proteins and antibodies at the nanoscale. Stability at physiological conditions, availability of various chemical modifications, and ease of synthesis have made DNA a material of choice for nanoconstructions comparable to other biomaterials at the nanometer scale.
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Controllable self-assembly of nanoparticles is highly desirable for understanding various phenomena based on inter-particle interactions at nanoscale. This dissertation focuses on the use of self-assembling DNA nanostructures for organizing nanoparticles in two- and three-dimensional assemblies, and the development of strategies to conjugate biomolecules to nanoparticles. The organizational power of DNA was demonstrated by creating two-dimensional arrays of gold nanoparticles and quantum dots with precise control of periodicity and interparticle distances. Gold nanoparticles of different sizes were employed to exert control on the self-assembly of DNA nanotubes of variable configurations and diameters. Furthermore, DNA self-assembly was used to create three-dimensional nanostructures of nanoparticles, which can be used to understand the unique optical properties of complex nanoparticle systems. To make this organizational power of DNA nanostructures more reliable, strategies were developed to strengthen the bond between the gold nanoparticles and oligonucleotides. Using lipoic acid modified oligonuculeotides, the yield of patterning of gold nanoparticles was increased considerably, which made DNA self-assembly even more useful for controlling the distances between particles and understanding their optical and magnetic properties.
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