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Kidney biomarkers = clinical aspects...

Ahuja, Seema S.

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Kidney biomarkers = clinical aspects and laboratory determination /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Kidney biomarkers/ edited by Seema S. Ahuja, Brian Castillo.
其他題名:	clinical aspects and laboratory determination /
其他作者:	Ahuja, Seema S.
出版者:	Amsterdam :Academic Press, : 2020.,
面頁冊數:	1 online resource.
附註:	Includes index.
內容註:	Further reading -- Chapter 2: Utility of the ``omics' in kidney disease: Methods of analysis, sampling considerations, and technical approa ... -- Introduction -- Statistical methods in analysis and interpretation of biomarkers in kidney disease -- Metrics for prediction performance (diagnostic potential) -- Quantification of prediction performance -- True positive rate and false positive rate -- Receiver-operating characteristic curve -- Summary indices -- Area underthe ROC curve (AUC) -- Optimal prediction threshold -- Partial area under the curve
內容註:	Limitations of statistical metrics used for prediction performance -- Metrics to evaluating incremental diagnostic value -- Incremental value: How to evaluate? -- Improvement in discrimination -- Improvement in reclassification -- Net reclassification improvement -- Categorical net reclassification improvement -- Weighted net reclassification improvement -- Category-free net reclassification improvement -- Integrated discrimination improvement -- Decision and clinicaluse of analytic measures -- Recommendations for sample collection, storage, and preparation -- Tissue samples -- Biofluids
內容註:	Nontargeted versus targeted analysis -- Proteomics and metabolomics in nephrology -- Potential impact of proteomics and metabolomics in renal diseases -- Proteomics and the kidney -- The proteomics sample -- Urine -- Kidney tissue and cell culture -- Techniques used in proteome analysis -- Proteomics methods based on mass spectrometry -- First step: Protein separation -- Gel-based proteome analysis -- Gel-free proteome analysis -- Liquid chromatography (LC) -- Capillary electrophoresis -- Second step: Protein identification
內容註:	Two-dimensional gel electrophoresis coupled with mass spectrometry (2DE-MS) -- Liquid chromatography coupled to mass spectrometry (LC-MS/MS) -- Capillary electrophoresis coupled with mass spectrometry (CE-MS) -- Matrix-assisted laser desorption/ionization-time of flight coupled with mass spectrometry (MALDI-TOF/MS) -- Solid-phase chromatography coupled with mass spectrometry (SELDI-MS) -- Differential protein profiling -- Mass spectrometry -- (a) Peptide mass fingerprinting -- (b) Electrospray ionization -- (c) Peptide sequencing using tandem mass spectrometers
標題:	Kidneys - Diseases -
電子資源:	https://www.sciencedirect.com/science/book/9780128159231
ISBN:	9780128163740 (electronic bk.)

Kidney biomarkers = clinical aspects and laboratory determination /
Kidney biomarkersclinical aspects and laboratory determination /[electronic resource] :edited by Seema S. Ahuja, Brian Castillo. - Amsterdam :Academic Press,2020. - 1 online resource.

Includes index.

Further reading -- Chapter 2: Utility of the ``omics' in kidney disease: Methods of analysis, sampling considerations, and technical approa ... -- Introduction -- Statistical methods in analysis and interpretation of biomarkers in kidney disease -- Metrics for prediction performance (diagnostic potential) -- Quantification of prediction performance -- True positive rate and false positive rate -- Receiver-operating characteristic curve -- Summary indices -- Area underthe ROC curve (AUC) -- Optimal prediction threshold -- Partial area under the curve

ISBN: 9780128163740 (electronic bk.)Subjects--Topical Terms:

1364537
Kidneys
--DiseasesIndex Terms--Genre/Form:

542853
Electronic books.

LC Class. No.: RC902

Dewey Class. No.: 616.61075

Kidney biomarkers = clinical aspects and laboratory determination /
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300 $a 1 online resource.
500 $a Includes index.
505 8 $a Further reading -- Chapter 2: Utility of the ``omics' in kidney disease: Methods of analysis, sampling considerations, and technical approa ... -- Introduction -- Statistical methods in analysis and interpretation of biomarkers in kidney disease -- Metrics for prediction performance (diagnostic potential) -- Quantification of prediction performance -- True positive rate and false positive rate -- Receiver-operating characteristic curve -- Summary indices -- Area underthe ROC curve (AUC) -- Optimal prediction threshold -- Partial area under the curve
505 8 $a Limitations of statistical metrics used for prediction performance -- Metrics to evaluating incremental diagnostic value -- Incremental value: How to evaluate? -- Improvement in discrimination -- Improvement in reclassification -- Net reclassification improvement -- Categorical net reclassification improvement -- Weighted net reclassification improvement -- Category-free net reclassification improvement -- Integrated discrimination improvement -- Decision and clinicaluse of analytic measures -- Recommendations for sample collection, storage, and preparation -- Tissue samples -- Biofluids
505 8 $a Nontargeted versus targeted analysis -- Proteomics and metabolomics in nephrology -- Potential impact of proteomics and metabolomics in renal diseases -- Proteomics and the kidney -- The proteomics sample -- Urine -- Kidney tissue and cell culture -- Techniques used in proteome analysis -- Proteomics methods based on mass spectrometry -- First step: Protein separation -- Gel-based proteome analysis -- Gel-free proteome analysis -- Liquid chromatography (LC) -- Capillary electrophoresis -- Second step: Protein identification
505 8 $a Two-dimensional gel electrophoresis coupled with mass spectrometry (2DE-MS) -- Liquid chromatography coupled to mass spectrometry (LC-MS/MS) -- Capillary electrophoresis coupled with mass spectrometry (CE-MS) -- Matrix-assisted laser desorption/ionization-time of flight coupled with mass spectrometry (MALDI-TOF/MS) -- Solid-phase chromatography coupled with mass spectrometry (SELDI-MS) -- Differential protein profiling -- Mass spectrometry -- (a) Peptide mass fingerprinting -- (b) Electrospray ionization -- (c) Peptide sequencing using tandem mass spectrometers
650 0 $a Kidneys $x Diseases $x Molecular diagnosis. $3 1364537
650 0 $a Biochemical markers. $3 587592
650 7 $a Biochemical markers $v Atlases. $3 2072251
655 0 $a Electronic books. $2 lcsh $3 542853
700 1 $a Ahuja, Seema S. $3 3509713
700 1 $a Castillo, Brian. $3 3509714
856 4 0 $u https://www.sciencedirect.com/science/book/9780128159231