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Tight junctions in inflammation and ...

Bhat, Ajaz A.

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Tight junctions in inflammation and cancer

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Tight junctions in inflammation and cancer/ edited by Ajaz A. Bhat ... [et al.].
其他作者:	Bhat, Ajaz A.
出版者:	Singapore :Springer Nature Singapore : : 2023.,
面頁冊數:	xiii, 193 p. :ill., digital ;24 cm.
內容註:	Chapter 1. Inflammation and Cancer: Role of Tight Junctions -- Chapter 2. Regulation of tight junction by cadherin adhesion and its implication in inflammation and cancer -- Chapter 3. Tight junctions, epithelial-mesenchymal transition and cancer metastasis -- Chapter 4. Imaging techniques to study tight junctions -- Chapter 5. Tight junction proteins as emerging drug targets: Expanding the horizons from inflammation to cancer -- Chapter 6. Tight Junctions and signaling pathways in cancer -- Chapter 7. Molecular architecture and function of tight junctions -- Chapter 8. The role of tight junction proteins in cancer.
Contained By:	Springer Nature eBook
標題:	Endothelium - Tumors. -
電子資源:	https://doi.org/10.1007/978-981-99-2415-8
ISBN:	9789819924158

Tight junctions in inflammation and cancer
Tight junctions in inflammation and cancer[electronic resource] /edited by Ajaz A. Bhat ... [et al.]. - Singapore :Springer Nature Singapore :2023. - xiii, 193 p. :ill., digital ;24 cm.

Chapter 1. Inflammation and Cancer: Role of Tight Junctions -- Chapter 2. Regulation of tight junction by cadherin adhesion and its implication in inflammation and cancer -- Chapter 3. Tight junctions, epithelial-mesenchymal transition and cancer metastasis -- Chapter 4. Imaging techniques to study tight junctions -- Chapter 5. Tight junction proteins as emerging drug targets: Expanding the horizons from inflammation to cancer -- Chapter 6. Tight Junctions and signaling pathways in cancer -- Chapter 7. Molecular architecture and function of tight junctions -- Chapter 8. The role of tight junction proteins in cancer.

This book provides an updated account of tight junctions of different epithelia and endothelia and addresses their anatomy, biochemistry, physiology, synthesis, assembly, and modulation. It also discusses the relationship between molecular structure, function, regulation, posttranslational modifications of tight junction proteins and their role in gut microbiota maintenance, epithelial-mesenchymal transition, and intestinal barrier dysfunction-associated disorders important for the progression of human cancers. This book presents the pathological alterations of tight junctions at the blood-brain barrier that intensify or even initiate neurological dysfunction. Further, it reviews the significance of tight junctions and tight junction proteins in cancer development, infectious diseases, allergic reactions, and autoimmune disorders. Lastly, it highlights strategies for modulating tight junctions to enhance drug availability and organ deposition. This book is immensely useful for basic, translational, clinical, and interdisciplinary cancer researchers, practicing oncologists, and immunologists.

ISBN: 9789819924158

Standard No.: 10.1007/978-981-99-2415-8doiSubjects--Topical Terms:

3667187
Endothelium
--Tumors.

LC Class. No.: QH603.C4 / T54 2023

Dewey Class. No.: 571.6

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520 $a This book provides an updated account of tight junctions of different epithelia and endothelia and addresses their anatomy, biochemistry, physiology, synthesis, assembly, and modulation. It also discusses the relationship between molecular structure, function, regulation, posttranslational modifications of tight junction proteins and their role in gut microbiota maintenance, epithelial-mesenchymal transition, and intestinal barrier dysfunction-associated disorders important for the progression of human cancers. This book presents the pathological alterations of tight junctions at the blood-brain barrier that intensify or even initiate neurological dysfunction. Further, it reviews the significance of tight junctions and tight junction proteins in cancer development, infectious diseases, allergic reactions, and autoimmune disorders. Lastly, it highlights strategies for modulating tight junctions to enhance drug availability and organ deposition. This book is immensely useful for basic, translational, clinical, and interdisciplinary cancer researchers, practicing oncologists, and immunologists.
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