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Atherosclerotic carotid plaque chara...

Shi, Hairong.

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Atherosclerotic carotid plaque characterization using ultrasound and elastography.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Atherosclerotic carotid plaque characterization using ultrasound and elastography./
Author:	Shi, Hairong.
Description:	284 p.
Notes:	Adviser: Tomy Varghese.
Contained By:	Dissertation Abstracts International68-04B.
Subject:	Biology, Animal Physiology. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3261441

Atherosclerotic carotid plaque characterization using ultrasound and elastography.
Shi, Hairong.

Atherosclerotic carotid plaque characterization using ultrasound and elastography. - 284 p.

Adviser: Tomy Varghese.

Thesis (Ph.D.)--The University of Wisconsin - Madison, 2007.

In this dissertation, we explore the feasibility of utilizing clinical ultrasound systems to study both ultrasonic and elastographic parameters for carotid plaque characterization.Subjects--Topical Terms:

1017835
Biology, Animal Physiology.

Atherosclerotic carotid plaque characterization using ultrasound and elastography.
LDR:02595nam 2200301 a 45 001 965667
005 20110906
008 110906s2007 eng d
035 $a (UMI)AAI3261441
035 $a AAI3261441
040 $a UMI $c UMI
100 1 $a Shi, Hairong. $3 1288436
245 1 0 $a Atherosclerotic carotid plaque characterization using ultrasound and elastography.
300 $a 284 p.
500 $a Adviser: Tomy Varghese.
500 $a Source: Dissertation Abstracts International, Volume: 68-04, Section: B, page: 2306.
502 $a Thesis (Ph.D.)--The University of Wisconsin - Madison, 2007.
520 $a In this dissertation, we explore the feasibility of utilizing clinical ultrasound systems to study both ultrasonic and elastographic parameters for carotid plaque characterization.
520 $a In in-vitro studies, we estimated the: (1) ultrasonic attenuation coefficient using a novel power difference method; (2) scattering parameter related to size using both Faran's scattering theory and the Gaussian correlation model for excised plaque specimens. For elastographic imaging, we utilized the strain ratio as a normalized indicator of relative stiffness. The combination of attenuation coefficient, scattering parameter related to size and strain ratio improves the ultrasound tissue characterization and classification ability.
520 $a A two-dimensional multi-level strain estimation method was developed for estimating displacement and strains in carotid artery plaque in-vivo. In-vivo ultrasonic tissue characterization analysis also demonstrate that attenuation and scattering parameter related to size are significantly different in soft and calcified plaques. The combination of the attenuation coefficient and scattering parameter related to size estimated using Faran's scattering theory illustrates that these two parameters can be utilized to distinguish between calcified and soft plaque under in-vivo imaging conditions. The maximum accumulated axial strain and the maximum relative lateral shift values computed from the strain images over the cardiac cycle also provide differentiation between soft and calcified plaques. ROC analysis and Support Vector Machine algorithms were also utilized to evaluate the performance of combinations of these parameters to classify plaque.
590 $a School code: 0262.
650 4 $a Biology, Animal Physiology. $3 1017835
650 4 $a Biophysics, Medical. $3 1017681
650 4 $a Health Sciences, Radiology. $3 1019076
690 $a 0433
690 $a 0574
690 $a 0760
710 2 0 $a The University of Wisconsin - Madison. $3 626640
773 0 $t Dissertation Abstracts International $g 68-04B.
790 $a 0262
790 1 0 $a Varghese, Tomy, $e advisor
791 $a Ph.D.
792 $a 2007
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3261441