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The transmission, detection and occu...

Boone, Stephanie All'anea.

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The transmission, detection and occurrence of viruses on indoor environmental fomites.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	The transmission, detection and occurrence of viruses on indoor environmental fomites./
Author:	Boone, Stephanie All'anea.
Description:	99 p.
Notes:	Adviser: Charles P. Gerba.
Contained By:	Dissertation Abstracts International66-12B.
Subject:	Biology, Microbiology. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3200613
ISBN:	9780542459726

The transmission, detection and occurrence of viruses on indoor environmental fomites.
Boone, Stephanie All'anea.

The transmission, detection and occurrence of viruses on indoor environmental fomites. - 99 p.

Adviser: Charles P. Gerba.

Thesis (Ph.D.)--The University of Arizona, 2006.

Viruses cause 60% of human infections and are probably the most common cause of infectious disease acquired indoors. Rapid spread of viral illness in indoor establishments facilitates disease morbidity and mortality. The goal of this dissertation is to clarify the role of fomites in the viral infection cycle. Research methods include investigation of published literature, and the use of polymerase chain reaction (PCR) for viral detection.

ISBN: 9780542459726Subjects--Topical Terms:

1017734
Biology, Microbiology.

The transmission, detection and occurrence of viruses on indoor environmental fomites.
LDR:03231nam 2200313 a 45 001 964187
005 20110901
008 110901s2006 eng d
020 $a 9780542459726
035 $a (UMI)AAI3200613
035 $a AAI3200613
040 $a UMI $c UMI
100 1 $a Boone, Stephanie All'anea. $3 1287256
245 1 4 $a The transmission, detection and occurrence of viruses on indoor environmental fomites.
300 $a 99 p.
500 $a Adviser: Charles P. Gerba.
500 $a Source: Dissertation Abstracts International, Volume: 66-12, Section: B, page: 6406.
502 $a Thesis (Ph.D.)--The University of Arizona, 2006.
520 $a Viruses cause 60% of human infections and are probably the most common cause of infectious disease acquired indoors. Rapid spread of viral illness in indoor establishments facilitates disease morbidity and mortality. The goal of this dissertation is to clarify the role of fomites in the viral infection cycle. Research methods include investigation of published literature, and the use of polymerase chain reaction (PCR) for viral detection.
520 $a The Appendix A study reviewed published literature to assess the significance of fomites in the transmission of ten common respiratory and enteric viruses (rhinovirus, respiratory syncytial virus (RSV), influenza A, parainfluenza 1 (HPIV1), coronavirus, rotavirus, calicivirus, hepatitis A virus (HAV), astrovirus and adenovirus). Results suggest that fomites play an important role in the transmission of common viral pathogens, and the use of disinfectants may limit the spread of viral disease. The Appendix B study examined PCR primer detection limits by determining the time length viruses can be isolated on fomites. Results indicated that poliovirus 1 and hepatitis A virus could be detected for up to 60 days. Parainfluenza 1 virus isolation yielded detection at 30 days and 50 days. Norovirus isolation yielded detection at 20 days and 30 days. Influenza virus isolation results were inconsistent, yielding no initial detection and detection up to 20 days. Appendix C assessed the occurrence of human parainfluenza 1 virus (HPIV1) on surfaces in office settings. HPIV1 was detected on 37% of fomites. HPIV1 was detected most on desktops (47%), and least on light switches (19%). Study results indicated a statistically significant difference between positive fomites in different buildings (Chi-square p< 0.011), and between building cubicles and conference room fomites (Chi-square p< 0.011). Appendix D evaluated the prevalence of influenza A virus on surfaces in day care and home settings. Influenza A was isolated on 23% of fall day care fomites and 53% of spring day care fomites. Influenza was isolated on 59% of home fomites sampled during March, and no influenza was detected on home fomites sampled during the summer. Overall, Influenza A virus was isolated on over 50% of fomites in homes and day care centers.
590 $a School code: 0009.
650 4 $a Biology, Microbiology. $3 1017734
650 4 $a Engineering, Environmental. $3 783782
650 4 $a Environmental Sciences. $3 676987
650 4 $a Health Sciences, Public Health. $3 1017659
690 $a 0410
690 $a 0573
690 $a 0768
690 $a 0775
710 2 0 $a The University of Arizona. $3 1017508
773 0 $t Dissertation Abstracts International $g 66-12B.
790 $a 0009
790 1 0 $a Gerba, Charles P., $e advisor
791 $a Ph.D.
792 $a 2006
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3200613