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Novel polymeric structures and drug ...

Goodwin, Andrew Pratt.

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Novel polymeric structures and drug release mechanisms for cancer therapy.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Novel polymeric structures and drug release mechanisms for cancer therapy./
Author:	Goodwin, Andrew Pratt.
Description:	127 p.
Notes:	Adviser: Jean M. J. Frechet.
Contained By:	Dissertation Abstracts International68-08B.
Subject:	Chemistry, Organic. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3275426
ISBN:	9780549167976

Novel polymeric structures and drug release mechanisms for cancer therapy.
Goodwin, Andrew Pratt.

Novel polymeric structures and drug release mechanisms for cancer therapy. - 127 p.

Adviser: Jean M. J. Frechet.

Thesis (Ph.D.)--University of California, Berkeley, 2007.

This dissertation describes the efforts toward the improvement of drug delivery systems with novel polymer designs. Incorporation of polymers can produce water soluble, nontoxic, long circulating drug delivery vehicles that can transport drugs lacking these properties. A challenge facing this field is the design of polymer carriers with high degrees of drug incorporation. In Chapter 2, a new method is described to produce dendrimers capable of loading multiple functional molecules on their periphery. Another problem is the method by which the drug is removed from the polymer. Chapter 3 describes the use of acetals as drug linkages with tunable rates of release. The final chapters of this work describe the design, demonstration, and implementation of micelles sensitive to near infrared light.

ISBN: 9780549167976Subjects--Topical Terms:

516206
Chemistry, Organic.

Novel polymeric structures and drug release mechanisms for cancer therapy.
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020 $a 9780549167976
035 $a (UMI)AAI3275426
035 $a AAI3275426
040 $a UMI $c UMI
100 1 $a Goodwin, Andrew Pratt. $3 1280723
245 1 0 $a Novel polymeric structures and drug release mechanisms for cancer therapy.
300 $a 127 p.
500 $a Adviser: Jean M. J. Frechet.
500 $a Source: Dissertation Abstracts International, Volume: 68-08, Section: B, page: 5237.
502 $a Thesis (Ph.D.)--University of California, Berkeley, 2007.
520 $a This dissertation describes the efforts toward the improvement of drug delivery systems with novel polymer designs. Incorporation of polymers can produce water soluble, nontoxic, long circulating drug delivery vehicles that can transport drugs lacking these properties. A challenge facing this field is the design of polymer carriers with high degrees of drug incorporation. In Chapter 2, a new method is described to produce dendrimers capable of loading multiple functional molecules on their periphery. Another problem is the method by which the drug is removed from the polymer. Chapter 3 describes the use of acetals as drug linkages with tunable rates of release. The final chapters of this work describe the design, demonstration, and implementation of micelles sensitive to near infrared light.
590 $a School code: 0028.
650 4 $a Chemistry, Organic. $3 516206
650 4 $a Chemistry, Pharmaceutical. $3 550957
650 4 $a Chemistry, Polymer. $3 1018428
690 $a 0490
690 $a 0491
690 $a 0495
710 2 $a University of California, Berkeley. $3 687832
773 0 $t Dissertation Abstracts International $g 68-08B.
790 $a 0028
790 1 0 $a Frechet, Jean M. J., $e advisor
791 $a Ph.D.
792 $a 2007
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3275426