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Reducing prescription drug abuse by ...

Coleman, John J.

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Reducing prescription drug abuse by design.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Reducing prescription drug abuse by design./
Author:	Coleman, John J.
Description:	352 p.
Notes:	Adviser: Susan J. Tolchin.
Contained By:	Dissertation Abstracts International68-03B.
Subject:	Health Sciences, Pharmacy. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3255787

Reducing prescription drug abuse by design.
Coleman, John J.

Reducing prescription drug abuse by design. - 352 p.

Adviser: Susan J. Tolchin.

Thesis (Ph.D.)--George Mason University, 2007.

According a recent government report, the nonmedical use of prescription drugs is the second most prevalent form of illicit drug abuse in the U.S. today. Nonmedical use of lawfully manufactured drugs is estimated to cost the American economy more than Subjects--Topical Terms:

1017737
Health Sciences, Pharmacy.

Reducing prescription drug abuse by design.
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008 110525s2007 ||||||||||||||||| ||eng d
035 $a (UMI)AAI3255787
035 $a AAI3255787
040 $a UMI $c UMI
100 1 $a Coleman, John J. $3 1273651
245 1 0 $a Reducing prescription drug abuse by design.
300 $a 352 p.
500 $a Adviser: Susan J. Tolchin.
500 $a Source: Dissertation Abstracts International, Volume: 68-03, Section: B, page: 1585.
502 $a Thesis (Ph.D.)--George Mason University, 2007.
520 $a According a recent government report, the nonmedical use of prescription drugs is the second most prevalent form of illicit drug abuse in the U.S. today. Nonmedical use of lawfully manufactured drugs is estimated to cost the American economy more than $2 00 billion annually. Supply-side regulatory measures developed almost a century ago appear ineffective today for controlling this form of drug abuse and may even impinge upon healthcare. In this study, we examine a theory for reducing prescription drug abuse by employing abuse-resistant technology in the composition and design of abusable drugs. We test this hypothesis by comparing estimated abuse levels for drugs containing the same active ingredient but using different design characteristics, including some that appear to inhibit abuse. Results: In every instance, drugs employing abuse-resistant designs showed significantly lower estimated abuse levels than comparator drugs without such designs. In addition, recommendations for implementing suggested regulatory policy changes are presented and discussed.
590 $a School code: 0883.
650 4 $a Health Sciences, Pharmacy. $3 1017737
650 4 $a Health Sciences, Public Health. $3 1017659
690 $a 0572
690 $a 0573
710 2 $a George Mason University. $3 1019450
773 0 $t Dissertation Abstracts International $g 68-03B.
790 $a 0883
790 1 0 $a Tolchin, Susan J., $e advisor
791 $a Ph.D.
792 $a 2007
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3255787