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Micro/nanoparticle synthesis by micr...

Hung, Lung-Hsin.

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Micro/nanoparticle synthesis by microfluidic devices for biomedical applications.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Micro/nanoparticle synthesis by microfluidic devices for biomedical applications./
Author:	Hung, Lung-Hsin.
Description:	101 p.
Notes:	Adviser: Abraham Phillip Lee.
Contained By:	Dissertation Abstracts International68-12B.
Subject:	Chemistry, Polymer. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3295244
ISBN:	9780549386438

Micro/nanoparticle synthesis by microfluidic devices for biomedical applications.
Hung, Lung-Hsin.

Micro/nanoparticle synthesis by microfluidic devices for biomedical applications. - 101 p.

Adviser: Abraham Phillip Lee.

Thesis (Ph.D.)--University of California, Irvine, 2007.

Microfluidic systems have advantages such as low sample consumption, fast reaction over conventional bench top processes and were demonstrated the abilities to generate high quality droplets and particles with narrow size distribution. Divided by material category, recent development of using microfluidic devices for semiconductor, metal, colloidal, and biomaterial particle synthesis were reviewed. Microfluidic systems were designed and fabricated accordingly by applications and upon surface modification for droplet generation and particle synthesis purpose. Poly (dimethylsiloxane) and solvent compatible thiolene adhesive were used as device materials, and soft lithography and molding method were utilized for fast device fabrication. Droplet generation and manipulation were demonstrated in microchannels with adjustable generation rate, size, ratio, and controllable droplet fusion and switch. Base on microfluidic systems and droplet technique, three methods, chemical reaction, solvent evaporation, solvent extraction were applied to generate cadmium sulfide and poly (lactide-co-glycolide) micro/nanoparticles. The sizes of synthesized particles range from 5nm (CdS) to 160mum (PLGA) in diameter with narrow size distribution. By utilizing microfluidic platforms more novel particle synthesis can be prepared and applied for drug delivery and biomedical applications.

ISBN: 9780549386438Subjects--Topical Terms:

1018428
Chemistry, Polymer.

Micro/nanoparticle synthesis by microfluidic devices for biomedical applications.
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020 $a 9780549386438
035 $a (UMI)AAI3295244
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100 1 $a Hung, Lung-Hsin. $3 1272434
245 1 0 $a Micro/nanoparticle synthesis by microfluidic devices for biomedical applications.
300 $a 101 p.
500 $a Adviser: Abraham Phillip Lee.
500 $a Source: Dissertation Abstracts International, Volume: 68-12, Section: B, page: 8178.
502 $a Thesis (Ph.D.)--University of California, Irvine, 2007.
520 $a Microfluidic systems have advantages such as low sample consumption, fast reaction over conventional bench top processes and were demonstrated the abilities to generate high quality droplets and particles with narrow size distribution. Divided by material category, recent development of using microfluidic devices for semiconductor, metal, colloidal, and biomaterial particle synthesis were reviewed. Microfluidic systems were designed and fabricated accordingly by applications and upon surface modification for droplet generation and particle synthesis purpose. Poly (dimethylsiloxane) and solvent compatible thiolene adhesive were used as device materials, and soft lithography and molding method were utilized for fast device fabrication. Droplet generation and manipulation were demonstrated in microchannels with adjustable generation rate, size, ratio, and controllable droplet fusion and switch. Base on microfluidic systems and droplet technique, three methods, chemical reaction, solvent evaporation, solvent extraction were applied to generate cadmium sulfide and poly (lactide-co-glycolide) micro/nanoparticles. The sizes of synthesized particles range from 5nm (CdS) to 160mum (PLGA) in diameter with narrow size distribution. By utilizing microfluidic platforms more novel particle synthesis can be prepared and applied for drug delivery and biomedical applications.
590 $a School code: 0030.
650 4 $a Chemistry, Polymer. $3 1018428
650 4 $a Engineering, Biomedical. $3 1017684
650 4 $a Engineering, Materials Science. $3 1017759
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710 2 $a University of California, Irvine. $3 705821
773 0 $t Dissertation Abstracts International $g 68-12B.
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791 $a Ph.D.
792 $a 2007
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3295244