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Effects of STZ induced hyperglycemia...

University of New Hampshire.

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Effects of STZ induced hyperglycemia and hyperlipemia on PPARgamma and ABCA1 in a hamster model of atherogenesis.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Effects of STZ induced hyperglycemia and hyperlipemia on PPARgamma and ABCA1 in a hamster model of atherogenesis./
Author:	LaMarca, Craig.
Description:	99 p.
Notes:	Adviser: Thomas Foxall.
Contained By:	Masters Abstracts International45-01.
Subject:	Agriculture, Animal Pathology. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1437632
ISBN:	9780542853067

Effects of STZ induced hyperglycemia and hyperlipemia on PPARgamma and ABCA1 in a hamster model of atherogenesis.
LaMarca, Craig.

Effects of STZ induced hyperglycemia and hyperlipemia on PPARgamma and ABCA1 in a hamster model of atherogenesis. - 99 p.

Adviser: Thomas Foxall.

Thesis (M.S.)--University of New Hampshire, 2006.

Diabetes mellitus accelerates atherogenesis, but the exact mechanisms involved are unknown. This study examined the effects of hyperglycemia on the inflammatory transcription factor peroxisome proliferator activated receptor gamma (PPARgamma), known to be involved in atherogenesis, and the ATP binding cassette A1 (ABCA1) protein that is a downstream product of PPARgamma. ABCA1 is a membrane bound transporter that is involved in reverse cholesterol transport via high density lipoprotein cholesterol (HDL-C). Hamsters were divided into two groups; hyperlipemic animals fed a high fat/high cholesterol control diet (C) and hyperlipemic/hyperglycemic animals that received the high fat diet and were administered streptozotocin. Half of the hamsters (23) in each group were sacrificed at 8 weeks and the other half at 24 weeks. (Abstract shortened by UMI.)

ISBN: 9780542853067Subjects--Topical Terms:

1021764
Agriculture, Animal Pathology.

Effects of STZ induced hyperglycemia and hyperlipemia on PPARgamma and ABCA1 in a hamster model of atherogenesis.
LDR:01749nam 2200277 a 45 001 940925
005 20110518
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020 $a 9780542853067
035 $a (UMI)AAI1437632
035 $a AAI1437632
040 $a UMI $c UMI
100 1 $a LaMarca, Craig. $3 1265061
245 1 0 $a Effects of STZ induced hyperglycemia and hyperlipemia on PPARgamma and ABCA1 in a hamster model of atherogenesis.
300 $a 99 p.
500 $a Adviser: Thomas Foxall.
500 $a Source: Masters Abstracts International, Volume: 45-01, page: 0204.
502 $a Thesis (M.S.)--University of New Hampshire, 2006.
520 $a Diabetes mellitus accelerates atherogenesis, but the exact mechanisms involved are unknown. This study examined the effects of hyperglycemia on the inflammatory transcription factor peroxisome proliferator activated receptor gamma (PPARgamma), known to be involved in atherogenesis, and the ATP binding cassette A1 (ABCA1) protein that is a downstream product of PPARgamma. ABCA1 is a membrane bound transporter that is involved in reverse cholesterol transport via high density lipoprotein cholesterol (HDL-C). Hamsters were divided into two groups; hyperlipemic animals fed a high fat/high cholesterol control diet (C) and hyperlipemic/hyperglycemic animals that received the high fat diet and were administered streptozotocin. Half of the hamsters (23) in each group were sacrificed at 8 weeks and the other half at 24 weeks. (Abstract shortened by UMI.)
590 $a School code: 0141.
650 4 $a Agriculture, Animal Pathology. $3 1021764
650 4 $a Biology, Animal Physiology. $3 1017835
690 $a 0433
690 $a 0476
710 2 $a University of New Hampshire. $3 1017788
773 0 $t Masters Abstracts International $g 45-01.
790 $a 0141
790 1 0 $a Foxall, Thomas, $e advisor
791 $a M.S.
792 $a 2006
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1437632