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Temperature estimation with ultrasound.

The University of Wisconsin - Madison.

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Temperature estimation with ultrasound.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Temperature estimation with ultrasound./
Author:	Daniels, Matthew.
Description:	264 p.
Notes:	Adviser: Tomy Varghese.
Contained By:	Dissertation Abstracts International69-09B.
Subject:	Health Sciences, Radiology. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3327894
ISBN:	9780549804338

Temperature estimation with ultrasound.
Daniels, Matthew.

Temperature estimation with ultrasound. - 264 p.

Adviser: Tomy Varghese.

Thesis (Ph.D.)--The University of Wisconsin - Madison, 2008.

Hepatocelluar carcinoma is the fastest growing type of cancer in the United States. In addition, the survival rate after one year is approximately zero without treatment. In many instances, patients with hepatocelluar carcinoma may not be suitable candidates for the primary treatment options, i.e. surgical resection or liver transplantation. This has led to the development of minimally invasive therapies focused on destroying hepatocelluar by thermal or chemical methods.

ISBN: 9780549804338Subjects--Topical Terms:

1019076
Health Sciences, Radiology.

Temperature estimation with ultrasound.
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020 $a 9780549804338
035 $a (UMI)AAI3327894
035 $a AAI3327894
040 $a UMI $c UMI
100 1 $a Daniels, Matthew. $3 1025793
245 1 0 $a Temperature estimation with ultrasound.
300 $a 264 p.
500 $a Adviser: Tomy Varghese.
500 $a Source: Dissertation Abstracts International, Volume: 69-09, Section: B, page: 5466.
502 $a Thesis (Ph.D.)--The University of Wisconsin - Madison, 2008.
520 $a Hepatocelluar carcinoma is the fastest growing type of cancer in the United States. In addition, the survival rate after one year is approximately zero without treatment. In many instances, patients with hepatocelluar carcinoma may not be suitable candidates for the primary treatment options, i.e. surgical resection or liver transplantation. This has led to the development of minimally invasive therapies focused on destroying hepatocelluar by thermal or chemical methods.
520 $a The focus of this dissertation is on the development of ultrasound-based image-guided monitoring options for minimally invasive therapies such as radiofrequency ablation. Ultrasound-based temperature imaging relies on relating the gradient of locally estimated tissue displacements to a temperature change. First, a realistic Finite Element Analysis/ultrasound simulation of ablation was developed. This allowed evaluation of the ability of ultrasound-based temperature estimation algorithms to track temperatures for three different ablation scenarios in the liver. It was found that 2-Dimensional block matching and a 6 second time step was able to accurately track the temperature over a 12 minute ablation procedure.
520 $a Next, a tissue-mimicking phantom was constructed to determine the accuracy of the temperature estimation method by comparing estimated temperatures to that measured using invasive fiber-optic temperature probes. The 2-Dimensional block matching was able to track the temperature accurately over the entire 8 minute heating procedure in the tissue-mimicking phantom. Finally, two separate in-vivo experiments were performed. The first experiment examined the ability of our algorithm to track frame-to-frame displacements when external motion due to respiration and the cardiac cycle were considered. It was determined that a frame rate between 13 frames per second and 33 frames per second was sufficient to track frame-to-frame displacements between respiratory cycles. The second experiment examined the ability of a novel dynamic frame selection based temperature algorithm to track temperatures during ablation of porcine kidney tissue. Here a novel multi-level 2-Dimensional cross-correlation algorithm was required to accurately track the temperature over an 8 minute ablation procedure.
590 $a School code: 0262.
650 4 $a Health Sciences, Radiology. $3 1019076
650 4 $a Physics, Acoustics. $3 1019086
690 $a 0574
690 $a 0986
710 2 $a The University of Wisconsin - Madison. $3 626640
773 0 $t Dissertation Abstracts International $g 69-09B.
790 $a 0262
790 1 0 $a Varghese, Tomy, $e advisor
791 $a Ph.D.
792 $a 2008
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3327894