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Nucleus accumbens neurons encode Pav...

The University of North Carolina at Chapel Hill., Psychology.

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Nucleus accumbens neurons encode Pavlovian approach behaviors: Evidence from an autoshaping paradigm.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Nucleus accumbens neurons encode Pavlovian approach behaviors: Evidence from an autoshaping paradigm./
Author:	Day, Jeremy Jason.
Description:	48 p.
Notes:	Adviser: Regina M. Carelli.
Contained By:	Masters Abstracts International45-06.
Subject:	Biology, Neuroscience. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1444061

Nucleus accumbens neurons encode Pavlovian approach behaviors: Evidence from an autoshaping paradigm.
Day, Jeremy Jason.

Nucleus accumbens neurons encode Pavlovian approach behaviors: Evidence from an autoshaping paradigm. - 48 p.

Adviser: Regina M. Carelli.

Thesis (M.A.)--The University of North Carolina at Chapel Hill, 2007.

Environmental stimuli predictive of appetitive events can elicit Pavlovian approach responses that enhance an organism's ability to track and secure natural rewards. We examined the activity of individual nucleus accumbens (NAc) neurons during the performance of approach behaviors. Animals were presented with conditioned stimuli that were either positive (the CS+) or negative (the CS-) predictors of reward. Approach responses directed at these cues were recorded as lever presses and were significantly more likely to occur during CS+ presentations. On the test day, 75% of NAc neurons exhibited changes in firing rate (termed 'phasically active') during CS+ presentations. Of these cells, 47% were characterized by time-locked increases in cell firing while 53% showed reductions in firing for the duration of the CS+. The same cells typically showed little or no change during CS- presentations. These results suggest that NAc neurons encode reward prediction and/or approach responses elicited by reward-paired cues.Subjects--Topical Terms:

1017680
Biology, Neuroscience.

Nucleus accumbens neurons encode Pavlovian approach behaviors: Evidence from an autoshaping paradigm.
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035 $a (UMI)AAI1444061
035 $a AAI1444061
040 $a UMI $c UMI
100 1 $a Day, Jeremy Jason. $3 1017868
245 1 0 $a Nucleus accumbens neurons encode Pavlovian approach behaviors: Evidence from an autoshaping paradigm.
300 $a 48 p.
500 $a Adviser: Regina M. Carelli.
500 $a Source: Masters Abstracts International, Volume: 45-06, page: 3324.
502 $a Thesis (M.A.)--The University of North Carolina at Chapel Hill, 2007.
520 $a Environmental stimuli predictive of appetitive events can elicit Pavlovian approach responses that enhance an organism's ability to track and secure natural rewards. We examined the activity of individual nucleus accumbens (NAc) neurons during the performance of approach behaviors. Animals were presented with conditioned stimuli that were either positive (the CS+) or negative (the CS-) predictors of reward. Approach responses directed at these cues were recorded as lever presses and were significantly more likely to occur during CS+ presentations. On the test day, 75% of NAc neurons exhibited changes in firing rate (termed 'phasically active') during CS+ presentations. Of these cells, 47% were characterized by time-locked increases in cell firing while 53% showed reductions in firing for the duration of the CS+. The same cells typically showed little or no change during CS- presentations. These results suggest that NAc neurons encode reward prediction and/or approach responses elicited by reward-paired cues.
590 $a School code: 0153.
650 4 $a Biology, Neuroscience. $3 1017680
650 4 $a Psychology, Experimental. $3 517106
650 4 $a Psychology, Physiological. $3 1017869
690 $a 0317
690 $a 0623
690 $a 0989
710 2 $a The University of North Carolina at Chapel Hill. $b Psychology. $3 1017867
773 0 $t Masters Abstracts International $g 45-06.
790 $a 0153
790 1 0 $a Carelli, Regina M., $e advisor
791 $a M.A.
792 $a 2007
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1444061