東華大學圖書館 |

Language: English

Help

回圖書館首頁

手機版館藏查詢

Back

Switch To: Labeled | MARC Mode | ISBD

Sequesteration of Lead, Cadmium and ...

Monachese, Marc Alberto,

Linked to FindBook

Google Book

Amazon

博客來

Sequesteration of Lead, Cadmium and Arsenic by Lactobacillus Species and Detoxication Potential /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Sequesteration of Lead, Cadmium and Arsenic by Lactobacillus Species and Detoxication Potential // Marc Alberto Monachese.
Author:	Monachese, Marc Alberto,
Description:	1 electronic resource (155 pages)
Notes:	Source: Masters Abstracts International, Volume: 84-02.
Contained By:	Masters Abstracts International84-02.
Subject:	Lead content. -
Online resource:	https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=29239946
ISBN:	9798841584988

Sequesteration of Lead, Cadmium and Arsenic by Lactobacillus Species and Detoxication Potential /
Monachese, Marc Alberto,

Sequesteration of Lead, Cadmium and Arsenic by Lactobacillus Species and Detoxication Potential /Marc Alberto Monachese. - 1 electronic resource (155 pages)

Source: Masters Abstracts International, Volume: 84-02.

Toxic metals are a class of elements with no biological role but with extreme toxicity. On average only 50% of ingested toxins are absorbed into the human body, for reasons still unknown. It was hypothesized that the gut microbiota plays a role in reducing toxin absorbance. The aim of this study was to determine if constituents of the gut, namely Lactobacillus species, are able to sequester arsenic, lead and cadmium from the environment. Lactobacilli were incubated with the metals, both in vitro and with a Caco-2 cell line. Analysis of metal concentrations was conducted to determine if these were reduced by lactobacilli and if this in turn lowered mortality of the Caco-2 cells, and to establish if lactobacilli could block transport of metals across a cell layer. In vitro studies and electron microscopy showed that lactobacilli had significant binding potential to the metals lead and cadmium. In addition, they conferred protection of Caco-2 cells from toxicity with less metal binding to the epithelial cell surfaces. This supports my hypothesis and raises the concept of using probiotic lactobacilli, perhaps in a food formulation, to reduce heavy metal exposure and poisoning. A yogurt formulation was created using two strains with metal-binding potential, and this could be tested in the future.

English

ISBN: 9798841584988Subjects--Topical Terms:

3687496
Lead content.

Sequesteration of Lead, Cadmium and Arsenic by Lactobacillus Species and Detoxication Potential /
LDR:02654nmm a22003973i 4500 001 2437317
005 20251119142753.5
006 m o d
007 cr|nu||||||||
008 261011s2012 miu||||||m |||||||eng d
020 $a 9798841584988
035 $a (MiAaPQD)AAI29239946
035 $a (MiAaPQD)oaiirlibuwocaetd1916
035 $a AAI29239946
040 $a MiAaPQD $b eng $c MiAaPQD $e rda
100 1 $a Monachese, Marc Alberto, $e author. $3 3828253
245 1 0 $a Sequesteration of Lead, Cadmium and Arsenic by Lactobacillus Species and Detoxication Potential / $c Marc Alberto Monachese.
264 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2012
300 $a 1 electronic resource (155 pages)
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
500 $a Source: Masters Abstracts International, Volume: 84-02.
500 $a Advisors: Reid, Gregor Committee members: Bend, Jack; Southam, Gordon.
502 $b M.Sc. $c The University of Western Ontario (Canada) $d 2012.
520 $a Toxic metals are a class of elements with no biological role but with extreme toxicity. On average only 50% of ingested toxins are absorbed into the human body, for reasons still unknown. It was hypothesized that the gut microbiota plays a role in reducing toxin absorbance. The aim of this study was to determine if constituents of the gut, namely Lactobacillus species, are able to sequester arsenic, lead and cadmium from the environment. Lactobacilli were incubated with the metals, both in vitro and with a Caco-2 cell line. Analysis of metal concentrations was conducted to determine if these were reduced by lactobacilli and if this in turn lowered mortality of the Caco-2 cells, and to establish if lactobacilli could block transport of metals across a cell layer. In vitro studies and electron microscopy showed that lactobacilli had significant binding potential to the metals lead and cadmium. In addition, they conferred protection of Caco-2 cells from toxicity with less metal binding to the epithelial cell surfaces. This supports my hypothesis and raises the concept of using probiotic lactobacilli, perhaps in a food formulation, to reduce heavy metal exposure and poisoning. A yogurt formulation was created using two strains with metal-binding potential, and this could be tested in the future.
546 $a English
590 $a School code: 0784
650 4 $a Lead content. $3 3687496
650 4 $a Food contamination & poisoning. $3 3562624
650 4 $a Soil contamination. $3 3557940
650 4 $a Arsenic. $3 3564838
650 4 $a Scanning electron microscopy. $3 551366
650 4 $a Analytical chemistry. $3 3168300
650 4 $a Chemistry. $3 516420
650 4 $a Food science. $3 3173303
650 4 $a Soil sciences. $3 2122699
690 $a 0486
690 $a 0485
690 $a 0359
690 $a 0481
710 2 $a The University of Western Ontario (Canada). $e degree granting institution. $3 3759225
720 1 $a Reid, Gregor $e degree supervisor.
773 0 $t Masters Abstracts International $g 84-02.
790 $a 0784
791 $a M.Sc.
792 $a 2012
856 4 0 $u https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=29239946