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Modifiers of PM2.5 Associated Health...

Narain, Morgan N.,

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Modifiers of PM2.5 Associated Health Effects in Vulnerable Populations /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Modifiers of PM2.5 Associated Health Effects in Vulnerable Populations // Morgan N Narain.
Author:	Narain, Morgan N.,
Description:	1 electronic resource (100 pages)
Notes:	Source: Dissertations Abstracts International, Volume: 86-11, Section: B.
Contained By:	Dissertations Abstracts International86-11B.
Subject:	Environmental health. -
Online resource:	https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=31939112
ISBN:	9798315712282

Modifiers of PM2.5 Associated Health Effects in Vulnerable Populations /
Narain, Morgan N.,

Modifiers of PM2.5 Associated Health Effects in Vulnerable Populations /Morgan N Narain. - 1 electronic resource (100 pages)

Source: Dissertations Abstracts International, Volume: 86-11, Section: B.

Fine particulate matter (PM2.5) exposure is a global health issue linked to increased mortality, cardiovascular problems, and hospital visits. The impact of PM2.5 varies based on factors like clinical condition, age, social determinants of health, location, and medication use. This study examines how clinical conditions and medication impact PM2.5 outcomes in patients with COVID-19 and heart failure (HF). PM2.5 is associated with cardiovascular issues, causing dysfunction through various pathways. One area not fully explored is how commonly prescribed medications affect sensitivity to PM2.5, especially in patients with cardiovascular disease who typically have high medication usage. We focused on HF patients due to their heightened sensitivity to PM2.5 and significant medication use, specifically examining β-blockers, ACE inhibitors, and ARBs.Our findings indicate that these medications reduce the impact of short-term PM2.5 exposure on vital signs in HF patients and an animal model. We also looked into adding environmental data to predict 30-day readmissions in COVID-19 patients, considering the connections between PM2.5, social determinants of health, and readmissions. These studies aim to enhance our understanding of the link between the environment and health, identify mechanisms by which PM2.5 causes vascular dysfunction, and reveal how environmental pollutants and socioeconomic factors influence health outcomes.

English

ISBN: 9798315712282Subjects--Topical Terms:

543032
Environmental health.
Subjects--Index Terms:

Air pollution

Modifiers of PM2.5 Associated Health Effects in Vulnerable Populations /
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100 1 $a Narain, Morgan N., $e author. $3 3827297
245 1 0 $a Modifiers of PM2.5 Associated Health Effects in Vulnerable Populations / $c Morgan N Narain.
264 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2025
300 $a 1 electronic resource (100 pages)
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500 $a Source: Dissertations Abstracts International, Volume: 86-11, Section: B.
500 $a Advisors: Ward-Caviness, Cavin Committee members: Kelada, Samir; Rager, Julia; Furey, Terry; Moriera-Bahnson, Edward; Jaspers, Ilona.
502 $b Ph.D. $c The University of North Carolina at Chapel Hill $d 2025.
520 $a Fine particulate matter (PM2.5) exposure is a global health issue linked to increased mortality, cardiovascular problems, and hospital visits. The impact of PM2.5 varies based on factors like clinical condition, age, social determinants of health, location, and medication use. This study examines how clinical conditions and medication impact PM2.5 outcomes in patients with COVID-19 and heart failure (HF). PM2.5 is associated with cardiovascular issues, causing dysfunction through various pathways. One area not fully explored is how commonly prescribed medications affect sensitivity to PM2.5, especially in patients with cardiovascular disease who typically have high medication usage. We focused on HF patients due to their heightened sensitivity to PM2.5 and significant medication use, specifically examining β-blockers, ACE inhibitors, and ARBs.Our findings indicate that these medications reduce the impact of short-term PM2.5 exposure on vital signs in HF patients and an animal model. We also looked into adding environmental data to predict 30-day readmissions in COVID-19 patients, considering the connections between PM2.5, social determinants of health, and readmissions. These studies aim to enhance our understanding of the link between the environment and health, identify mechanisms by which PM2.5 causes vascular dysfunction, and reveal how environmental pollutants and socioeconomic factors influence health outcomes.
546 $a English
590 $a School code: 0153
650 4 $a Environmental health. $3 543032
650 4 $a Epidemiology. $3 568544
650 4 $a Public health. $3 534748
650 4 $a Toxicology. $3 556884
650 4 $a Environmental science. $3 677245
653 $a Air pollution
653 $a Cardiovascular disease
653 $a COVID-19
653 $a Social determinants of health
653 $a Vulnerable populations
690 $a 0470
690 $a 0766
690 $a 0768
690 $a 0573
690 $a 0383
710 2 $a The University of North Carolina at Chapel Hill. $b Toxicology. $e degree granting institution. $3 3823856
720 1 $a Ward-Caviness, Cavin $e degree supervisor.
773 0 $t Dissertations Abstracts International $g 86-11B.
790 $a 0153
791 $a Ph.D.
792 $a 2025
856 4 0 $u https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=31939112