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Advanced Applications Using Radial M...

Zi, Ruoxun,

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Advanced Applications Using Radial MRI and Iterative Reconstruction Techniques /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Advanced Applications Using Radial MRI and Iterative Reconstruction Techniques // Ruoxun Zi.
作者:	Zi, Ruoxun,
面頁冊數:	1 electronic resource (164 pages)
附註:	Source: Dissertations Abstracts International, Volume: 86-12, Section: B.
Contained By:	Dissertations Abstracts International86-12B.
標題:	Biomedical engineering. -
電子資源:	https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=31846582
ISBN:	9798286425488

Advanced Applications Using Radial MRI and Iterative Reconstruction Techniques /
Zi, Ruoxun,

Advanced Applications Using Radial MRI and Iterative Reconstruction Techniques /Ruoxun Zi. - 1 electronic resource (164 pages)

Source: Dissertations Abstracts International, Volume: 86-12, Section: B.

Magnetic resonance (MR) imaging (MRI) based on radial k-space sampling offers various advantages, including high motion robustness, incoherent undersampling properties, and capability for self-navigation, making it well-suited for free-breathing scans with accelerated data acquisition and integrated motion correction. Additionally, when combined with compressed-sensing, radial MRI enables flexible contrast manipulation and highly accelerated dynamic imaging using advanced reconstruction algorithms such as GRASP. Motivated by these properties, the overarching goal of this thesis was to further develop the potential of radial acquisition techniques and to investigate applications that uniquely benefit from the sampling scheme. Four novel MR imaging techniques based on radial k-space sampling were developed.The first project focused on fat suppression at 0.55 T, which has gained strong interest due to the lower costs associated with low field scanners. The reduction in main magnetic field strength leads to significant challenges for fat suppression from the narrow spectral fat/water distance. To address this limitation, we developed an alternative approach that sweeps the frequency of radiofrequency saturation pulses during a continuous radial acquisition and calculates frequency-resolved images using regularized iterative reconstruction. The proposed principle achieves reliable fat suppression in low-field applications and adapts to high-field applications with strong main field inhomogeneities. Moreover, the principle can potentially be extended toward proton density fat fraction (PDFF) quantification.In the second project, I developed radial versions of a novel class of pulse-sequences for contrast-enhanced brain MRI. T1 Relaxation-Enhanced Steady-State (T1RESS) sequences have been proposed as an alternative to the widely used magnetization-prepared rapid gradient-echo (MP-RAGE) sequence, offering improved lesion conspicuity and effective suppression of blood vessels. Three radial T1RESS variants were developed with different acquisition schemes, along with three technical extensions to further enhance their performance. The radial T1RESS sequences were evaluated in patients for brain and neck imaging, demonstrating improved conspicuity of enhancing lesions, robustness to motion, and the ability to provide simultaneous dynamic contrast-enhanced (DCE) imaging.The third project investigated the use of the Pilot-Tone (PT) technique for the detection of respiratory motion in free-breathing abdominopelvic DCE MRI, where self-navigation approaches typically fail due to the concurrency of respiratory and contrast-induced signal variations at the k-space center. A pipeline for extracting respiratory curves from data acquired using a body coil with integrated PT transmitter was developed and applied for motion-weighted GRASP reconstruction in free-breathing abdominopelvic DCE-MRI, which resulted in improved image sharpness and temporal consistency. The final project focused on dynamic volumetric wrist MRI for functional kinematic assessment. Most existing real-time MRI methods are either limited due to their 2D nature or provide only low temporal resolution and insufficient image quality. To address this challenge, I developed a novel approach for dynamic volumetric wrist examination that assembles 2D real-time MRI data into 3D snapshots. The reproducibility of the proposed method was validated in vivo for ulnar-radial deviation using a dedicated flexible wrist coil and a custom-made 3D-printed support platform for guiding wrist motion.

English

ISBN: 9798286425488Subjects--Topical Terms:

535387
Biomedical engineering.
Subjects--Index Terms:

Compressed-sensing reconstruction

Advanced Applications Using Radial MRI and Iterative Reconstruction Techniques /
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