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Exploiting Resonant Frequencies of t...

Jimeson, Alyssa Celeste,

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Exploiting Resonant Frequencies of the Human Eye to Reduce Intraocular Pressure for Open Angle Glaucoma /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Exploiting Resonant Frequencies of the Human Eye to Reduce Intraocular Pressure for Open Angle Glaucoma // Alyssa Celeste Jimeson.
Author:	Jimeson, Alyssa Celeste,
Description:	1 electronic resource (53 pages)
Notes:	Source: Masters Abstracts International, Volume: 86-02.
Contained By:	Masters Abstracts International86-02.
Subject:	Mechanical engineering. -
Online resource:	https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=31485180
ISBN:	9798383583289

Exploiting Resonant Frequencies of the Human Eye to Reduce Intraocular Pressure for Open Angle Glaucoma /
Jimeson, Alyssa Celeste,

Exploiting Resonant Frequencies of the Human Eye to Reduce Intraocular Pressure for Open Angle Glaucoma /Alyssa Celeste Jimeson. - 1 electronic resource (53 pages)

Source: Masters Abstracts International, Volume: 86-02.

Glaucoma is a group of eye conditions that when untreated leads to blindness. This disease damages the optic nerve, thus damaging the path for visual signals to the brain. For many types of glaucoma, high intraocular pressure is a well-known symptom that increases pressure on the optic nerve head, causing irreversible damage. The current treatments either try to promote fluid outflow or prevent fluid production of the eye. The treatments: eye drops, laser perforations, and surgery, have potential harmful side effects and are not suitable for everyone. This research focuses on exploiting the resonant frequencies of the eye structures to observe if it is possible to promote fluid outflow by exciting the drainage tissue without creating holes or stopping fluid production. Finite element simulations were configured in SolidWorks to compute the resonant frequencies of the eye structures. The simulations were utilized to discover frequencies that specifically resulted in high displacements of the drainage tissues. To validate the simulated results, an experimental set-up was created to replicate the fluid production structure, the ciliary body. A micro-pump connected to a series of syringes forced water through a needle into the anterior chamber of the eye, while a rocker arm coupled to a linear actuator transmitted the desired frequency. Simulations showed several promising physical modes at specific frequencies, but the physical experiments did not have a definitive conclusion. Results indicated that the drainage tissue in an ex vivo eye does not have the same behavior as an in vivo eye.

English

ISBN: 9798383583289Subjects--Topical Terms:

649730
Mechanical engineering.
Subjects--Index Terms:

Glaucoma

Exploiting Resonant Frequencies of the Human Eye to Reduce Intraocular Pressure for Open Angle Glaucoma /
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100 1 $a Jimeson, Alyssa Celeste, $e author. $3 3821821
245 1 0 $a Exploiting Resonant Frequencies of the Human Eye to Reduce Intraocular Pressure for Open Angle Glaucoma / $c Alyssa Celeste Jimeson.
264 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2024
300 $a 1 electronic resource (53 pages)
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500 $a Source: Masters Abstracts International, Volume: 86-02.
500 $a Advisors: Larson, Michael Committee members: Bredbenner, Todd; Stevens, James.
502 $b M.S. $c University of Colorado Colorado Springs $d 2024.
520 $a Glaucoma is a group of eye conditions that when untreated leads to blindness. This disease damages the optic nerve, thus damaging the path for visual signals to the brain. For many types of glaucoma, high intraocular pressure is a well-known symptom that increases pressure on the optic nerve head, causing irreversible damage. The current treatments either try to promote fluid outflow or prevent fluid production of the eye. The treatments: eye drops, laser perforations, and surgery, have potential harmful side effects and are not suitable for everyone. This research focuses on exploiting the resonant frequencies of the eye structures to observe if it is possible to promote fluid outflow by exciting the drainage tissue without creating holes or stopping fluid production. Finite element simulations were configured in SolidWorks to compute the resonant frequencies of the eye structures. The simulations were utilized to discover frequencies that specifically resulted in high displacements of the drainage tissues. To validate the simulated results, an experimental set-up was created to replicate the fluid production structure, the ciliary body. A micro-pump connected to a series of syringes forced water through a needle into the anterior chamber of the eye, while a rocker arm coupled to a linear actuator transmitted the desired frequency. Simulations showed several promising physical modes at specific frequencies, but the physical experiments did not have a definitive conclusion. Results indicated that the drainage tissue in an ex vivo eye does not have the same behavior as an in vivo eye.
546 $a English
590 $a School code: 0892
650 4 $a Mechanical engineering. $3 649730
650 4 $a Ophthalmology. $3 862704
650 4 $a Neurosciences. $3 588700
653 $a Glaucoma
653 $a Eye conditions
653 $a Optic nerve
653 $a Fluid production
653 $a Intraocular pressure
690 $a 0548
690 $a 0317
690 $a 0381
710 2 $a University of Colorado Colorado Springs. $b College of Engineering and Applied Science-Mechanical Engineering. $e degree granting institution. $3 3821822
720 1 $a Larson, Michael $e degree supervisor.
773 0 $t Masters Abstracts International $g 86-02.
790 $a 0892
791 $a M.S.
792 $a 2024
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