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Cardio-Metabolic Effects of One Hund...
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Knezevic, Steven,
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Cardio-Metabolic Effects of One Hundred Hours of Exoskeletal-Assisted Walking in Individuals With Spinal Cord Injury /
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
Cardio-Metabolic Effects of One Hundred Hours of Exoskeletal-Assisted Walking in Individuals With Spinal Cord Injury // Steven Knezevic.
作者:
Knezevic, Steven,
面頁冊數:
1 electronic resource (203 pages)
附註:
Source: Dissertations Abstracts International, Volume: 86-07, Section: B.
Contained By:
Dissertations Abstracts International86-07B.
標題:
Health sciences. -
電子資源:
https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=31768960
ISBN:
9798346892847
Cardio-Metabolic Effects of One Hundred Hours of Exoskeletal-Assisted Walking in Individuals With Spinal Cord Injury /
Knezevic, Steven,
Cardio-Metabolic Effects of One Hundred Hours of Exoskeletal-Assisted Walking in Individuals With Spinal Cord Injury /
Steven Knezevic. - 1 electronic resource (203 pages)
Source: Dissertations Abstracts International, Volume: 86-07, Section: B.
The prevalence of cardiovascular disease (CVD) is significantly higher in individuals with spinal cord injury (SCI) compared to able-bodied counterparts. Current upper body aerobic exercise modalities, such as arm crank ergometry and rowing, offer limited benefits to significantly improve CVD risk factors in SCI. While upright exoskeletal-assisted walking (EAW), improves cardiorespiratory fitness, its effects on CVD risk in SCI remain uncertain. This study aims to assess the impact of an EAW program on body composition and lipid profile in individuals with chronic incomplete SCI. Dual-energy x-ray absorptiometry obtained fat mass and lean mass measurements. Overnight fasted blood draws were analyzed for lipid profile parameters (High Density Lipoprotein Cholesterol, Low Density Lipoprotein Cholesterol; LDL-c, triglycerides, & total cholesterol). All outcome measures were collected at three points, baseline, 50-hours, and 100-hours. A linear mixed model and clinically significant changes (5% reduction for total body fat mass and 10% reduction for total LDL-c), were utilized to observe group and within-subject effects. Findings from 19 participants (13 paraplegia, 6 tetraplegia, & average body mass index 43.4 ± 6.0 kg/m²) yielded significant reductions in total body fat mass (0.70 ± 2.66 kgs, p = 0.047) and arm fat mass (0.11 ± 0.36 kgs, p = 0.042) post 100-hour EAW intervention. Clinically significant changes in total body fat mass were present in one third of participants (7/19). Of these participants, the majority had a paraplegia SCI (6/7) and a lower extremity motor score of 11 or higher (5/7). For lipid changes, 10 participants showed clinically significant improvements, with most of them also having paraplegia SCI (7/10) and a lower extremity motor score of 11 or higher (6/10). Statistical differences in pattern of change were found by level of injury (total body fat mass, total cholesterol, & LDL-c), lower extremity motor score (Visceral adipose tissue, leg lean mass, & total cholesterol), and time since SCI (High Density Lipoprotein Cholesterol). Findings of the present investigation demonstrate that EAW can contribute to the improvement of risks associated with CVD. The significant differences in pattern of change between subgroups support further investigating the implications of EAW across SCI subgroups for promoting optimal cardiovascular health across individuals with SCI.
English
ISBN: 9798346892847Subjects--Topical Terms:
3168359
Health sciences.
Subjects--Index Terms:
Cardiovascular disease
Cardio-Metabolic Effects of One Hundred Hours of Exoskeletal-Assisted Walking in Individuals With Spinal Cord Injury /
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The prevalence of cardiovascular disease (CVD) is significantly higher in individuals with spinal cord injury (SCI) compared to able-bodied counterparts. Current upper body aerobic exercise modalities, such as arm crank ergometry and rowing, offer limited benefits to significantly improve CVD risk factors in SCI. While upright exoskeletal-assisted walking (EAW), improves cardiorespiratory fitness, its effects on CVD risk in SCI remain uncertain. This study aims to assess the impact of an EAW program on body composition and lipid profile in individuals with chronic incomplete SCI. Dual-energy x-ray absorptiometry obtained fat mass and lean mass measurements. Overnight fasted blood draws were analyzed for lipid profile parameters (High Density Lipoprotein Cholesterol, Low Density Lipoprotein Cholesterol; LDL-c, triglycerides, & total cholesterol). All outcome measures were collected at three points, baseline, 50-hours, and 100-hours. A linear mixed model and clinically significant changes (5% reduction for total body fat mass and 10% reduction for total LDL-c), were utilized to observe group and within-subject effects. Findings from 19 participants (13 paraplegia, 6 tetraplegia, & average body mass index 43.4 ± 6.0 kg/m²) yielded significant reductions in total body fat mass (0.70 ± 2.66 kgs, p = 0.047) and arm fat mass (0.11 ± 0.36 kgs, p = 0.042) post 100-hour EAW intervention. Clinically significant changes in total body fat mass were present in one third of participants (7/19). Of these participants, the majority had a paraplegia SCI (6/7) and a lower extremity motor score of 11 or higher (5/7). For lipid changes, 10 participants showed clinically significant improvements, with most of them also having paraplegia SCI (7/10) and a lower extremity motor score of 11 or higher (6/10). Statistical differences in pattern of change were found by level of injury (total body fat mass, total cholesterol, & LDL-c), lower extremity motor score (Visceral adipose tissue, leg lean mass, & total cholesterol), and time since SCI (High Density Lipoprotein Cholesterol). Findings of the present investigation demonstrate that EAW can contribute to the improvement of risks associated with CVD. The significant differences in pattern of change between subgroups support further investigating the implications of EAW across SCI subgroups for promoting optimal cardiovascular health across individuals with SCI.
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