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Collective Problem Solving as an Inf...

Tung, Angela,

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Collective Problem Solving as an Influence on Morphogenesis /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Collective Problem Solving as an Influence on Morphogenesis // Angela Tung.
Author:	Tung, Angela,
Description:	1 electronic resource (250 pages)
Notes:	Source: Dissertations Abstracts International, Volume: 85-11, Section: B.
Contained By:	Dissertations Abstracts International85-11B.
Subject:	Biology. -
Online resource:	https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=31244364
ISBN:	9798382737454

Collective Problem Solving as an Influence on Morphogenesis /
Tung, Angela,

Collective Problem Solving as an Influence on Morphogenesis /Angela Tung. - 1 electronic resource (250 pages)

Source: Dissertations Abstracts International, Volume: 85-11, Section: B.

Not all sources of information for morphogenesis have yet to be identified, but it is crucial to do so in order to be able to innovate new therapies and prevent defects from forming. This dissertation points to the ability of lateral influences, specifically for collectives of conspecifics, to influence morphogenesis. Chapter 2 reviews the myriad of sources for which cells and organisms can receive information from outside the genome. Next, in chapter 3, I show that organisms are physiologically robust and can adapt to novel challenges in order to solve problematic situations. Specifically, I show that Dugesia japonica have a level of adaptive plasticity that allows them to survive in the face of a novel, physiological perturbation. After establishing that there are extra-genomic cues and illustrating the responsive versatility that exists when faced with unprecedented stressors, I introduce a novel mode of protection from morphogenetic defects in Xenopus laevis: collective conspecifics (chapter 4). By existing in a group, in which larger is better, there is a shielding effect against teratogens that increases survival and lowers rates of defect. Chapter 5 of this dissertation will investigate morphogenetic disorders through the lens of active inference. Here, computational modeling offers a new perspective on cellular collectives, computational modeling, and morphological abnormalities. A common thread between all the chapters is morphogenesis can be influenced by the capacity of an organism to integrate a wide range of informational inputs. This dissertation focuses on and introduces some of these informational inputs, specifically the profound contribution of collective behaviors.

English

ISBN: 9798382737454Subjects--Topical Terms:

522710
Biology.
Subjects--Index Terms:

Collective problem solving

Collective Problem Solving as an Influence on Morphogenesis /
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245 1 0 $a Collective Problem Solving as an Influence on Morphogenesis / $c Angela Tung.
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500 $a Source: Dissertations Abstracts International, Volume: 85-11, Section: B.
500 $a Advisors: Levin, Michael Committee members: McLaughlin, Kelly; McVey, Mitch; Cohen, Daniel.
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520 $a Not all sources of information for morphogenesis have yet to be identified, but it is crucial to do so in order to be able to innovate new therapies and prevent defects from forming. This dissertation points to the ability of lateral influences, specifically for collectives of conspecifics, to influence morphogenesis. Chapter 2 reviews the myriad of sources for which cells and organisms can receive information from outside the genome. Next, in chapter 3, I show that organisms are physiologically robust and can adapt to novel challenges in order to solve problematic situations. Specifically, I show that Dugesia japonica have a level of adaptive plasticity that allows them to survive in the face of a novel, physiological perturbation. After establishing that there are extra-genomic cues and illustrating the responsive versatility that exists when faced with unprecedented stressors, I introduce a novel mode of protection from morphogenetic defects in Xenopus laevis: collective conspecifics (chapter 4). By existing in a group, in which larger is better, there is a shielding effect against teratogens that increases survival and lowers rates of defect. Chapter 5 of this dissertation will investigate morphogenetic disorders through the lens of active inference. Here, computational modeling offers a new perspective on cellular collectives, computational modeling, and morphological abnormalities. A common thread between all the chapters is morphogenesis can be influenced by the capacity of an organism to integrate a wide range of informational inputs. This dissertation focuses on and introduces some of these informational inputs, specifically the profound contribution of collective behaviors.
546 $a English
590 $a School code: 0234
650 4 $a Biology. $3 522710
650 4 $a Morphology. $3 591167
650 4 $a Developmental biology. $3 592588
650 4 $a Physiology. $3 518431
650 4 $a Aquatic sciences. $3 3174300
653 $a Collective problem solving
653 $a Cross-embryo communication
653 $a Extra-genomics
653 $a Morphogenesis
653 $a Physiological plasticity
653 $a Xenopus laevis
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690 $a 0287
690 $a 0758
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710 2 $a Tufts University. $b Biology. $e degree granting institution. $3 3816852
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792 $a 2024
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