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FPGA-Based System for Radiation Ener...

Guntha, Pavan Sai,

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FPGA-Based System for Radiation Energy Histogram Computation Using Time-Over-Threshold /

Record Type:	Electronic resources : Monograph/item
Title/Author:	FPGA-Based System for Radiation Energy Histogram Computation Using Time-Over-Threshold // Pavan Sai Guntha.
Author:	Guntha, Pavan Sai,
Description:	1 electronic resource (96 pages)
Notes:	Source: Masters Abstracts International, Volume: 87-10.
Contained By:	Masters Abstracts International87-10.
Subject:	Electrical engineering. -
Online resource:	https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=32404682
ISBN:	9798241651662

FPGA-Based System for Radiation Energy Histogram Computation Using Time-Over-Threshold /
Guntha, Pavan Sai,

FPGA-Based System for Radiation Energy Histogram Computation Using Time-Over-Threshold /Pavan Sai Guntha. - 1 electronic resource (96 pages)

Source: Masters Abstracts International, Volume: 87-10.

Personalized dosimetry is essential for optimizing radiopharmaceutical therapy, yet current clinical practice relies on serial hospital imaging that is expensive and limits the number of time-point samples. This thesis presents an FPGA-based system used in the Portable Organ Dosimetry Device (PODD), a compact wireless gamma spectroscopy system for monitoring 177Lu therapy.This thesis focuses on the design and implementation of an FPGA-based real-time energy histogram computation system. The FPGA processes time-over-threshold encoded signals from 16 parallel detector channels, achieving 2.5ns time binning for pulse width measurement and maintaining 512-bin histograms per channel. The digital processing core integrates with GAGG:Ce/SiPM scintillation detectors and communicates wirelessly via Bluetooth to an Android application.Validation with 177Lu and 22Na radioactive sources demonstrated clearly resolved photopeaks at 113 keV, 208 keV, and 511 keV. The PODD's compact form factor and wireless operation enable accessible point-of-care dosimetry for personalized radiopharmaceutical therapy.

English

ISBN: 9798241651662Subjects--Topical Terms:

649834
Electrical engineering.
Subjects--Index Terms:

Portable Organ Dosimetry Device

FPGA-Based System for Radiation Energy Histogram Computation Using Time-Over-Threshold /
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300 $a 1 electronic resource (96 pages)
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500 $a Source: Masters Abstracts International, Volume: 87-10.
500 $a Advisors: Hauck, Scott Committee members: Miyaoka, Robert.
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520 $a Personalized dosimetry is essential for optimizing radiopharmaceutical therapy, yet current clinical practice relies on serial hospital imaging that is expensive and limits the number of time-point samples. This thesis presents an FPGA-based system used in the Portable Organ Dosimetry Device (PODD), a compact wireless gamma spectroscopy system for monitoring 177Lu therapy.This thesis focuses on the design and implementation of an FPGA-based real-time energy histogram computation system. The FPGA processes time-over-threshold encoded signals from 16 parallel detector channels, achieving 2.5ns time binning for pulse width measurement and maintaining 512-bin histograms per channel. The digital processing core integrates with GAGG:Ce/SiPM scintillation detectors and communicates wirelessly via Bluetooth to an Android application.Validation with 177Lu and 22Na radioactive sources demonstrated clearly resolved photopeaks at 113 keV, 208 keV, and 511 keV. The PODD's compact form factor and wireless operation enable accessible point-of-care dosimetry for personalized radiopharmaceutical therapy.
546 $a English
590 $a School code: 0250
650 4 $a Electrical engineering. $3 649834
650 4 $a Biomedical engineering. $3 535387
650 4 $a Pharmaceutical sciences. $3 3173021
653 $a Portable Organ Dosimetry Device
653 $a Wireless gamma spectroscopy
653 $a Radiopharmaceutical therapy
653 $a Wireless operation
690 $a 0544
690 $a 0541
690 $a 0572
710 2 $a University of Washington. $b Electrical and Computer Engineering. $e degree granting institution. $3 3765649
720 1 $a Hauck, Scott $e degree supervisor.
773 0 $t Masters Abstracts International $g 87-10.
790 $a 0250
791 $a M.S.
792 $a 2026
856 4 0 $u https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=32404682