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The Impacts of Type 2 Diabetes and O...

Abdelmoneim, Fatima.

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The Impacts of Type 2 Diabetes and Obesity on Right Ventricle Function.

Record Type:	Electronic resources : Monograph/item
Title/Author:	The Impacts of Type 2 Diabetes and Obesity on Right Ventricle Function./
Author:	Abdelmoneim, Fatima.
Published:	Ann Arbor : ProQuest Dissertations & Theses, : 2023,
Description:	110 p.
Notes:	Source: Masters Abstracts International, Volume: 85-06.
Contained By:	Masters Abstracts International85-06.
Subject:	Bioengineering. -
Online resource:	https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=30575430
ISBN:	9798381157765

The Impacts of Type 2 Diabetes and Obesity on Right Ventricle Function.
Abdelmoneim, Fatima.

The Impacts of Type 2 Diabetes and Obesity on Right Ventricle Function. - Ann Arbor : ProQuest Dissertations & Theses, 2023 - 110 p.

Source: Masters Abstracts International, Volume: 85-06.

Thesis (M.S.)--University of Colorado at Denver, 2023.

The increasing prevalence of Type 2 Diabetes (T2D) has led to extensive research focusing on its impact on the left ventricle (LV) of the heart, while the role of the right ventricle (RV) remains understudied. However, the RV is linked to heart failure in individuals with T2D, and its dysfunction may manifest before clinical symptoms become apparent. Our study explores RV function in individuals with T2D and obesity using cardiac magnetic resonance (CMR) imaging, with sex differences. Pre-exercise analysis reveals that T2D and obesity are associated with lower RV volumes compared to a reference control group, with T2D showing more significant impairments. However, post-exercise analysis demonstrates improvements in RV function, particularly in the T2D group, indicating exercise's positive impact on RV function. Differences in ventricular function between males and females are also observed, with males demonstrating more improvement in right ventricular function after exercise. However, obese individuals exhibited minimal improvement in their RV function after exercise. These findings underscore the importance of exercise as a potential therapeutic intervention for improving right ventricular function in individuals with T2D, with potential sex-specific responses. All RV parameters strongly correlated with their corresponding LV parameters, specifically before exercise.

ISBN: 9798381157765Subjects--Topical Terms:

657580
Bioengineering.
Subjects--Index Terms:

Right ventricle function

The Impacts of Type 2 Diabetes and Obesity on Right Ventricle Function.
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245 1 0 $a The Impacts of Type 2 Diabetes and Obesity on Right Ventricle Function.
260 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2023
300 $a 110 p.
500 $a Source: Masters Abstracts International, Volume: 85-06.
500 $a Advisor: Hunter, Kendall.
502 $a Thesis (M.S.)--University of Colorado at Denver, 2023.
520 $a The increasing prevalence of Type 2 Diabetes (T2D) has led to extensive research focusing on its impact on the left ventricle (LV) of the heart, while the role of the right ventricle (RV) remains understudied. However, the RV is linked to heart failure in individuals with T2D, and its dysfunction may manifest before clinical symptoms become apparent. Our study explores RV function in individuals with T2D and obesity using cardiac magnetic resonance (CMR) imaging, with sex differences. Pre-exercise analysis reveals that T2D and obesity are associated with lower RV volumes compared to a reference control group, with T2D showing more significant impairments. However, post-exercise analysis demonstrates improvements in RV function, particularly in the T2D group, indicating exercise's positive impact on RV function. Differences in ventricular function between males and females are also observed, with males demonstrating more improvement in right ventricular function after exercise. However, obese individuals exhibited minimal improvement in their RV function after exercise. These findings underscore the importance of exercise as a potential therapeutic intervention for improving right ventricular function in individuals with T2D, with potential sex-specific responses. All RV parameters strongly correlated with their corresponding LV parameters, specifically before exercise.
590 $a School code: 0765.
650 4 $a Bioengineering. $3 657580
650 4 $a Medical imaging. $3 3172799
650 4 $a Endocrinology. $3 610914
653 $a Right ventricle function
653 $a Obesity
653 $a Type 2 Diabetes
653 $a Therapeutic intervention
690 $a 0202
690 $a 0574
690 $a 0409
710 2 $a University of Colorado at Denver. $b Bioengineering. $3 3170804
773 0 $t Masters Abstracts International $g 85-06.
790 $a 0765
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793 $a English
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