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Comparative Animal Mucomics.

Cerullo, Antonio R.

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Comparative Animal Mucomics.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Comparative Animal Mucomics./
Author:	Cerullo, Antonio R.
Published:	Ann Arbor : ProQuest Dissertations & Theses, : 2024,
Description:	195 p.
Notes:	Source: Dissertations Abstracts International, Volume: 85-08, Section: B.
Contained By:	Dissertations Abstracts International85-08B.
Subject:	Biochemistry. -
Online resource:	https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=30988841
ISBN:	9798381682793

Comparative Animal Mucomics.
Cerullo, Antonio R.

Comparative Animal Mucomics. - Ann Arbor : ProQuest Dissertations & Theses, 2024 - 195 p.

Source: Dissertations Abstracts International, Volume: 85-08, Section: B.

Thesis (Ph.D.)--City University of New York, 2024.

This item must not be sold to any third party vendors.

Mucus is one of Nature's most abundant and versatile biomaterials. These secretions are present in all animals, from the lowly garden snail to the great blue whale, and fulfill a multitude of functions, acting as antimicrobial barriers, moisturizers, adhesive glues, surface lubricants, and mineralizing agents. Despite their importance, very little is known about mucus compositions or properties. The largest challenge precluding the greater understanding of mucus function is its complexity; a single mucus contains complex mixtures of proteins, glycans, and ions that all have important roles in function. Therefore, understanding mucus function necessitates analysis that compares different mucus from one animal, or mucus of the same function from different species, and this approach must characterize mucus across the molecular-to-macroscopic continuum.This thesis aims to characterize the compositions and properties of animal mucus, determine the methods that best interrogate these materials, and justify the need to do so. Chapter 1 highlights secreted animal mucus diversity in Nature. Chapter 2 demonstrates our integrative omics approach comparing three mucus of different functions from the garden snail, Cornu aspersum. The Epilogue concludes with a call to expand mucus characterization efforts amidst a global biodiversity crisis.

ISBN: 9798381682793Subjects--Topical Terms:

518028
Biochemistry.
Subjects--Index Terms:

Animals

Comparative Animal Mucomics.
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100 1 $a Cerullo, Antonio R. $0 (orcid)0000-0002-8992-7755 $3 3767205
245 1 0 $a Comparative Animal Mucomics.
260 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2024
300 $a 195 p.
500 $a Source: Dissertations Abstracts International, Volume: 85-08, Section: B.
500 $a Advisor: Braunschweig, Adam B.
502 $a Thesis (Ph.D.)--City University of New York, 2024.
506 $a This item must not be sold to any third party vendors.
520 $a Mucus is one of Nature's most abundant and versatile biomaterials. These secretions are present in all animals, from the lowly garden snail to the great blue whale, and fulfill a multitude of functions, acting as antimicrobial barriers, moisturizers, adhesive glues, surface lubricants, and mineralizing agents. Despite their importance, very little is known about mucus compositions or properties. The largest challenge precluding the greater understanding of mucus function is its complexity; a single mucus contains complex mixtures of proteins, glycans, and ions that all have important roles in function. Therefore, understanding mucus function necessitates analysis that compares different mucus from one animal, or mucus of the same function from different species, and this approach must characterize mucus across the molecular-to-macroscopic continuum.This thesis aims to characterize the compositions and properties of animal mucus, determine the methods that best interrogate these materials, and justify the need to do so. Chapter 1 highlights secreted animal mucus diversity in Nature. Chapter 2 demonstrates our integrative omics approach comparing three mucus of different functions from the garden snail, Cornu aspersum. The Epilogue concludes with a call to expand mucus characterization efforts amidst a global biodiversity crisis.
590 $a School code: 0046.
650 4 $a Biochemistry. $3 518028
650 4 $a Animal sciences. $3 3174829
650 4 $a Genetics. $3 530508
653 $a Animals
653 $a Biomaterials
653 $a Mucus
653 $a Omics
653 $a Mucomics
690 $a 0487
690 $a 0475
690 $a 0369
710 2 $a City University of New York. $b Biochemistry. $3 1263127
773 0 $t Dissertations Abstracts International $g 85-08B.
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793 $a English
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