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A Semi-Supervised Learning Approach ...

Whang, Esther.

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A Semi-Supervised Learning Approach to Classifying Pathological Images of Heart Tissue for the Presence of Intercellular Junctions.

Record Type:	Electronic resources : Monograph/item
Title/Author:	A Semi-Supervised Learning Approach to Classifying Pathological Images of Heart Tissue for the Presence of Intercellular Junctions./
Author:	Whang, Esther.
Published:	Ann Arbor : ProQuest Dissertations & Theses, : 2023,
Description:	126 p.
Notes:	Source: Masters Abstracts International, Volume: 84-11.
Contained By:	Masters Abstracts International84-11.
Subject:	Medical imaging. -
Online resource:	https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=30490741
ISBN:	9798379507527

A Semi-Supervised Learning Approach to Classifying Pathological Images of Heart Tissue for the Presence of Intercellular Junctions.
Whang, Esther.

A Semi-Supervised Learning Approach to Classifying Pathological Images of Heart Tissue for the Presence of Intercellular Junctions. - Ann Arbor : ProQuest Dissertations & Theses, 2023 - 126 p.

Source: Masters Abstracts International, Volume: 84-11.

Thesis (M.E.)--The Cooper Union for the Advancement of Science and Art, 2023.

This item must not be sold to any third party vendors.

Developments in whole slide imaging and in computational analysis methods have opened the door to new discoveries in the field of medicine. In particular, machine learning has gained attention as a tool for analyzing large amounts of medical image data. However, while the ease of using machine learning systems makes them appealing, building the labeled datasets required to train these systems remains a difficult problem due to the need for trained professionals to annotate each data point. This work presents a machine learning-based classification pipeline that incorporates both labeled and unlabeled images, reducing the burden of building a fully-labeled dataset. The pipeline consists of a pretrained convolutional neural network feature extractor and a support vector machine classifier, with the feature extractor finetuned with MixMatch, a semi-supervised learning algorithm. Different training methods are explored based on the pretrained weights of the feature extractor and the ratio of labeled to unlabeled images used during training. The final classification pipelines are evaluated on a heart tissue dataset from The Human Protein Atlas that was annotated for the presence of intercalated discs by doctors at Johns Hopkins University. This approach achieves higher accuracy in classifying intercalated disc presence than a supervised learning-based pipeline.

ISBN: 9798379507527Subjects--Topical Terms:

3172799
Medical imaging.
Subjects--Index Terms:

Deep learning

A Semi-Supervised Learning Approach to Classifying Pathological Images of Heart Tissue for the Presence of Intercellular Junctions.
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245 1 2 $a A Semi-Supervised Learning Approach to Classifying Pathological Images of Heart Tissue for the Presence of Intercellular Junctions.
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300 $a 126 p.
500 $a Source: Masters Abstracts International, Volume: 84-11.
500 $a Advisor: Fontaine, Fred L.
502 $a Thesis (M.E.)--The Cooper Union for the Advancement of Science and Art, 2023.
506 $a This item must not be sold to any third party vendors.
520 $a Developments in whole slide imaging and in computational analysis methods have opened the door to new discoveries in the field of medicine. In particular, machine learning has gained attention as a tool for analyzing large amounts of medical image data. However, while the ease of using machine learning systems makes them appealing, building the labeled datasets required to train these systems remains a difficult problem due to the need for trained professionals to annotate each data point. This work presents a machine learning-based classification pipeline that incorporates both labeled and unlabeled images, reducing the burden of building a fully-labeled dataset. The pipeline consists of a pretrained convolutional neural network feature extractor and a support vector machine classifier, with the feature extractor finetuned with MixMatch, a semi-supervised learning algorithm. Different training methods are explored based on the pretrained weights of the feature extractor and the ratio of labeled to unlabeled images used during training. The final classification pipelines are evaluated on a heart tissue dataset from The Human Protein Atlas that was annotated for the presence of intercalated discs by doctors at Johns Hopkins University. This approach achieves higher accuracy in classifying intercalated disc presence than a supervised learning-based pipeline.
590 $a School code: 0057.
650 4 $a Medical imaging. $3 3172799
650 4 $a Biomedical engineering. $3 535387
653 $a Deep learning
653 $a Digital pathology
653 $a Machine learning
653 $a Semi-supervised learning
653 $a Whole slide imaging
690 $a 0800
690 $a 0574
690 $a 0541
710 2 $a The Cooper Union for the Advancement of Science and Art. $b Electrical Engineering. $3 2094848
773 0 $t Masters Abstracts International $g 84-11.
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791 $a M.E.
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793 $a English
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