東華大學圖書館 |

Language: English

Help

回圖書館首頁

手機版館藏查詢

Back

Switch To: Labeled | MARC Mode | ISBD

Genetic Analysis of Novel Traits in ...

Novo, Larissa Carolina.

Linked to FindBook

Google Book

Amazon

博客來

Genetic Analysis of Novel Traits in Holstein Dairy Cattle.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Genetic Analysis of Novel Traits in Holstein Dairy Cattle./
Author:	Novo, Larissa Carolina.
Published:	Ann Arbor : ProQuest Dissertations & Theses, : 2023,
Description:	145 p.
Notes:	Source: Dissertations Abstracts International, Volume: 85-03, Section: B.
Contained By:	Dissertations Abstracts International85-03B.
Subject:	Animal sciences. -
Online resource:	https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=30638141
ISBN:	9798380345293

Genetic Analysis of Novel Traits in Holstein Dairy Cattle.
Novo, Larissa Carolina.

Genetic Analysis of Novel Traits in Holstein Dairy Cattle. - Ann Arbor : ProQuest Dissertations & Theses, 2023 - 145 p.

Source: Dissertations Abstracts International, Volume: 85-03, Section: B.

Thesis (Ph.D.)--The University of Wisconsin - Madison, 2023.

This item must not be sold to any third party vendors.

The availability of new technologies, as well as a greater attention to the needs of consumers and society, has promoted the development of selection strategies for novel traits in dairy cattle. However, several steps must be followed from the proposal until the implementation of novel traits into breeding programs. This process requires efforts from the definition of the new trait, exploration of the genetic basis of the trait, the development of proper analysis methods, and finally the implementation of a genetic evaluation. This thesis addresses different aspects of the development and implementation of novel traits, including definition of the phenotype, better understanding of the biological processes affecting the trait, identification of putative causal variants and genes, and finally a feasibility study of a national genetic evaluation. Specifically, this thesis evaluated different body temperature phenotypes as potential indicators of feed efficiency traits, investigated visceral fat deposition and its relationship with metabolic disorders, uncovered putative causal variants for periparturient hypocalcemia, and explored the implementation of a national genetic evaluation for Johne's disease. The first study showed that body temperature can be used as an indicator of feed efficiency and energy-related traits. The second study revealed that visceral fat accumulation is associated with inflammation, insulin resistance, and immune response, and is genetically linked to displaced abomasum. The third study identified genetic variants and individual genes affecting postpartum blood calcium concentration. The last study showed that a national genetic evaluation for Johne's Disease in Holsteins is feasible. Overall, this work has performed a comprehensive investigation of the different steps required for the development and implementation of novel traits in dairy cattle.

ISBN: 9798380345293Subjects--Topical Terms:

3174829
Animal sciences.
Subjects--Index Terms:

Causal variants

Genetic Analysis of Novel Traits in Holstein Dairy Cattle.
LDR:03158nmm a2200409 4500 001 2393524
005 20240318062656.5
006 m o d
007 cr#unu||||||||
008 251215s2023 ||||||||||||||||| ||eng d
020 $a 9798380345293
035 $a (MiAaPQ)AAI30638141
035 $a AAI30638141
040 $a MiAaPQ $c MiAaPQ
100 1 $a Novo, Larissa Carolina. $3 3762993
245 1 0 $a Genetic Analysis of Novel Traits in Holstein Dairy Cattle.
260 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2023
300 $a 145 p.
500 $a Source: Dissertations Abstracts International, Volume: 85-03, Section: B.
500 $a Advisor: Penagaricano, Francisco.
502 $a Thesis (Ph.D.)--The University of Wisconsin - Madison, 2023.
506 $a This item must not be sold to any third party vendors.
520 $a The availability of new technologies, as well as a greater attention to the needs of consumers and society, has promoted the development of selection strategies for novel traits in dairy cattle. However, several steps must be followed from the proposal until the implementation of novel traits into breeding programs. This process requires efforts from the definition of the new trait, exploration of the genetic basis of the trait, the development of proper analysis methods, and finally the implementation of a genetic evaluation. This thesis addresses different aspects of the development and implementation of novel traits, including definition of the phenotype, better understanding of the biological processes affecting the trait, identification of putative causal variants and genes, and finally a feasibility study of a national genetic evaluation. Specifically, this thesis evaluated different body temperature phenotypes as potential indicators of feed efficiency traits, investigated visceral fat deposition and its relationship with metabolic disorders, uncovered putative causal variants for periparturient hypocalcemia, and explored the implementation of a national genetic evaluation for Johne's disease. The first study showed that body temperature can be used as an indicator of feed efficiency and energy-related traits. The second study revealed that visceral fat accumulation is associated with inflammation, insulin resistance, and immune response, and is genetically linked to displaced abomasum. The third study identified genetic variants and individual genes affecting postpartum blood calcium concentration. The last study showed that a national genetic evaluation for Johne's Disease in Holsteins is feasible. Overall, this work has performed a comprehensive investigation of the different steps required for the development and implementation of novel traits in dairy cattle.
590 $a School code: 0262.
650 4 $a Animal sciences. $3 3174829
650 4 $a Biology. $3 522710
650 4 $a Genetics. $3 530508
653 $a Causal variants
653 $a Genetic evaluation
653 $a Biological processes
653 $a Health traits
653 $a Whole-genome sequence
690 $a 0475
690 $a 0778
690 $a 0306
690 $a 0369
710 2 $a The University of Wisconsin - Madison. $b Animal Sciences. $3 2096734
773 0 $t Dissertations Abstracts International $g 85-03B.
790 $a 0262
791 $a Ph.D.
792 $a 2023
793 $a English
856 4 0 $u https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=30638141