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Biomarkers for Bovine Mammary Gland ...

Strickland, Jaimie Marie.

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Biomarkers for Bovine Mammary Gland Involution and Disease.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Biomarkers for Bovine Mammary Gland Involution and Disease./
Author:	Strickland, Jaimie Marie.
Published:	Ann Arbor : ProQuest Dissertations & Theses, : 2023,
Description:	209 p.
Notes:	Source: Dissertations Abstracts International, Volume: 84-08, Section: B.
Contained By:	Dissertations Abstracts International84-08B.
Subject:	Animal sciences. -
Online resource:	https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=29209693
ISBN:	9798371989215

Biomarkers for Bovine Mammary Gland Involution and Disease.
Strickland, Jaimie Marie.

Biomarkers for Bovine Mammary Gland Involution and Disease. - Ann Arbor : ProQuest Dissertations & Theses, 2023 - 209 p.

Source: Dissertations Abstracts International, Volume: 84-08, Section: B.

Thesis (Ph.D.)--Michigan State University, 2023.

This item must not be sold to any third party vendors.

Bovine mammary gland involution occurs after the abrupt cessation of lactation and involves a complex sequence of inflammatory processes, morphology changes, and mammary epithelial cell turnover. The mammary gland is vulnerable to bacterial infections in the first 3 weeks after dry off, especially if milk leakage occurs. Increased risk of milk leakage and infection are associated with high milk production at the end of lactation. Therefore, as advances in dairy cow genetics and management continue to increase milk production- more cows will be at risk for infection during early mammary involution. Many aspects of mammary gland involution remain unknown. Biomarkers can be used to predict disease, such as with plasma non-esterified fatty acids in close up dry cows. Biomarkers can also be used to monitor the effect of treatment or intervention. There is not strong evidence that many of the current biomarkers for mammary gland involution, such as lactoferrin, are associated with disease risk or improved involution. Thus, this dissertation is centered around the association of certain biomarkers (fat soluble vitamins and lipid mediators) with mammary gland involution, oxidative stress, and diseases in dairy cows.

ISBN: 9798371989215Subjects--Topical Terms:

3174829
Animal sciences.
Subjects--Index Terms:

Biomarker

Biomarkers for Bovine Mammary Gland Involution and Disease.
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035 $a AAI29209693
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100 1 $a Strickland, Jaimie Marie. $0 (orcid)0000-0002-6629-4051 $3 3762891
245 1 0 $a Biomarkers for Bovine Mammary Gland Involution and Disease.
260 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2023
300 $a 209 p.
500 $a Source: Dissertations Abstracts International, Volume: 84-08, Section: B.
500 $a Advisor: Ruegg, Pamela L.;Sordillo, Lorraine M.
502 $a Thesis (Ph.D.)--Michigan State University, 2023.
506 $a This item must not be sold to any third party vendors.
520 $a Bovine mammary gland involution occurs after the abrupt cessation of lactation and involves a complex sequence of inflammatory processes, morphology changes, and mammary epithelial cell turnover. The mammary gland is vulnerable to bacterial infections in the first 3 weeks after dry off, especially if milk leakage occurs. Increased risk of milk leakage and infection are associated with high milk production at the end of lactation. Therefore, as advances in dairy cow genetics and management continue to increase milk production- more cows will be at risk for infection during early mammary involution. Many aspects of mammary gland involution remain unknown. Biomarkers can be used to predict disease, such as with plasma non-esterified fatty acids in close up dry cows. Biomarkers can also be used to monitor the effect of treatment or intervention. There is not strong evidence that many of the current biomarkers for mammary gland involution, such as lactoferrin, are associated with disease risk or improved involution. Thus, this dissertation is centered around the association of certain biomarkers (fat soluble vitamins and lipid mediators) with mammary gland involution, oxidative stress, and diseases in dairy cows.
590 $a School code: 0128.
650 4 $a Animal sciences. $3 3174829
650 4 $a Immunology. $3 611031
653 $a Biomarker
653 $a Dairy cow
653 $a Mammary involution
653 $a Mastitis
653 $a Vitamin
690 $a 0475
690 $a 0982
710 2 $a Michigan State University. $b Comparative Medicine and Integrative Biology - Doctor of Philosophy. $3 2093084
773 0 $t Dissertations Abstracts International $g 84-08B.
790 $a 0128
791 $a Ph.D.
792 $a 2023
793 $a English
856 4 0 $u https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=29209693