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Covalent Attachment of Polyaspartic Acid to Experimental Resin-Based Materials for the Microinvasive Treatment of White Spot Lesions : = An in Vitro Pilot Study.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Covalent Attachment of Polyaspartic Acid to Experimental Resin-Based Materials for the Microinvasive Treatment of White Spot Lesions :/
其他題名:	An in Vitro Pilot Study.
作者:	Venditelli, Matthew Paul .
面頁冊數:	1 online resource (104 pages)
附註:	Source: Masters Abstracts International, Volume: 84-09.
Contained By:	Masters Abstracts International84-09.
標題:	Dentistry. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=29993205click for full text (PQDT)
ISBN:	9798377615545

Covalent Attachment of Polyaspartic Acid to Experimental Resin-Based Materials for the Microinvasive Treatment of White Spot Lesions : = An in Vitro Pilot Study.
Venditelli, Matthew Paul .

Covalent Attachment of Polyaspartic Acid to Experimental Resin-Based Materials for the Microinvasive Treatment of White Spot Lesions :An in Vitro Pilot Study. - 1 online resource (104 pages)

Source: Masters Abstracts International, Volume: 84-09.

Thesis (M.Sc.)--University of Toronto (Canada), 2023.

Includes bibliographical references

Background: Resin infiltrants can be improved through the addition of bioactive molecules. A bioactive molecule capable of promoting hydroxyapatite development is polyaspartic acid, pAsp. Objective: This in vitro study assessed the material properties of experimental resin-based materials. Methods: Artificial white spot lesions on extracted human premolars (n=60) were treated with resin-based materials, Prime&Bond™ (Dentsply Sirona, North Carolina, USA) or Icon™ (DMG, Hamburg, Germany), containing pAsp (passive or covalent) or unmodified. After remineralization, specimens were assessed for penetration depth (μm) through Confocal Microscopy, and surface nanohardness (GPa) and Young's modulus (GPa) through Diamond Berkovich Indenter. Two-way ANOVA followed by Tukey post-hoc test was used to analyze data, a=0.05. Results: Covalent attachment of pAsp significantly increased penetration depth compared to passive addition pAsp to resin-based materials (p=0.013). Conclusion: To our knowledge this is the first study to covalently attach pAsp to resin-based materials targeted for the treatment of white spot enamel lesions.

Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2023

Mode of access: World Wide Web

ISBN: 9798377615545Subjects--Topical Terms:

828971
Dentistry.
Subjects--Index Terms:

Covalent bondIndex Terms--Genre/Form:

542853
Electronic books.

Covalent Attachment of Polyaspartic Acid to Experimental Resin-Based Materials for the Microinvasive Treatment of White Spot Lesions : = An in Vitro Pilot Study.
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520 $a Background: Resin infiltrants can be improved through the addition of bioactive molecules. A bioactive molecule capable of promoting hydroxyapatite development is polyaspartic acid, pAsp. Objective: This in vitro study assessed the material properties of experimental resin-based materials. Methods: Artificial white spot lesions on extracted human premolars (n=60) were treated with resin-based materials, Prime&Bond™ (Dentsply Sirona, North Carolina, USA) or Icon™ (DMG, Hamburg, Germany), containing pAsp (passive or covalent) or unmodified. After remineralization, specimens were assessed for penetration depth (μm) through Confocal Microscopy, and surface nanohardness (GPa) and Young's modulus (GPa) through Diamond Berkovich Indenter. Two-way ANOVA followed by Tukey post-hoc test was used to analyze data, a=0.05. Results: Covalent attachment of pAsp significantly increased penetration depth compared to passive addition pAsp to resin-based materials (p=0.013). Conclusion: To our knowledge this is the first study to covalently attach pAsp to resin-based materials targeted for the treatment of white spot enamel lesions.
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