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Healthcare Associated Infections in Singapore with a Focus on Infections Caused by Carbapenem Resistant Gram Negative Bacteria.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Healthcare Associated Infections in Singapore with a Focus on Infections Caused by Carbapenem Resistant Gram Negative Bacteria./
Author:	Yiying, Cai.
Description:	1 online resource (224 pages)
Notes:	Source: Dissertations Abstracts International, Volume: 83-07, Section: B.
Contained By:	Dissertations Abstracts International83-07B.
Subject:	Infectious diseases. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=28832942click for full text (PQDT)
ISBN:	9798460445998

Healthcare Associated Infections in Singapore with a Focus on Infections Caused by Carbapenem Resistant Gram Negative Bacteria.
Yiying, Cai.

Healthcare Associated Infections in Singapore with a Focus on Infections Caused by Carbapenem Resistant Gram Negative Bacteria. - 1 online resource (224 pages)

Source: Dissertations Abstracts International, Volume: 83-07, Section: B.

Thesis (Ph.D.)--National University of Singapore (Singapore), 2020.

Includes bibliographical references

This thesis examined healthcare associated infections (HAIs) and HAIs caused by carbapenem-resistant (CR) Gram-negative bacteria (GNB) in Singapore. In a nationwide HAI point prevalence survey, one in nine adult inpatients admitted to Singapore hospitals had at least 1 HAI(s). Compared to patients without HAIs, patients with HAIs had increased length of stay and mortality risks. Risk factors for CR-GNB HAIs included prior carbapenem exposure, prior fluoroquinolone exposure and presence of drains. Compared to patients with carbapenem-susceptible GNB HAIs, patients with CR-GNB HAIs had significantly longer time to discharge. This translated to a markedly higher costs to hospitals. In patients with CR-GNB HAI patients who received different polymyxin B-based treatment, those who received treatment guided in vitro antibiotic combination testing had improved clinical outcomes. In summary, HAIs and CR-GNB HAIs are important public health problems in Singapore. A multi-pronged approach is necessary to reduce HAIs and combat carbapenem resistance among GNB.

Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2023

Mode of access: World Wide Web

ISBN: 9798460445998Subjects--Topical Terms:

2179310
Infectious diseases.
Index Terms--Genre/Form:

542853
Electronic books.

Healthcare Associated Infections in Singapore with a Focus on Infections Caused by Carbapenem Resistant Gram Negative Bacteria.
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035 $a AAI28832942
040 $a MiAaPQ $b eng $c MiAaPQ $d NTU
100 1 $a Yiying, Cai. $3 3695776
245 1 0 $a Healthcare Associated Infections in Singapore with a Focus on Infections Caused by Carbapenem Resistant Gram Negative Bacteria.
264 0 $c 2020
300 $a 1 online resource (224 pages)
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
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500 $a Source: Dissertations Abstracts International, Volume: 83-07, Section: B.
502 $a Thesis (Ph.D.)--National University of Singapore (Singapore), 2020.
504 $a Includes bibliographical references
520 $a This thesis examined healthcare associated infections (HAIs) and HAIs caused by carbapenem-resistant (CR) Gram-negative bacteria (GNB) in Singapore. In a nationwide HAI point prevalence survey, one in nine adult inpatients admitted to Singapore hospitals had at least 1 HAI(s). Compared to patients without HAIs, patients with HAIs had increased length of stay and mortality risks. Risk factors for CR-GNB HAIs included prior carbapenem exposure, prior fluoroquinolone exposure and presence of drains. Compared to patients with carbapenem-susceptible GNB HAIs, patients with CR-GNB HAIs had significantly longer time to discharge. This translated to a markedly higher costs to hospitals. In patients with CR-GNB HAI patients who received different polymyxin B-based treatment, those who received treatment guided in vitro antibiotic combination testing had improved clinical outcomes. In summary, HAIs and CR-GNB HAIs are important public health problems in Singapore. A multi-pronged approach is necessary to reduce HAIs and combat carbapenem resistance among GNB.
533 $a Electronic reproduction. $b Ann Arbor, Mich. : $c ProQuest, $d 2023
538 $a Mode of access: World Wide Web
650 4 $a Infectious diseases. $3 2179310
650 4 $a Ventilators. $3 3685015
650 4 $a Disease prevention. $3 3685279
650 4 $a Length of stay. $3 3560751
650 4 $a Mortality. $3 533218
650 4 $a Urinary tract infections. $3 3445680
650 4 $a Drug resistance. $3 1602664
650 4 $a Drug dosages. $3 3557732
650 4 $a Southeast Asian studies. $3 3344898
650 4 $a Epidemiology. $3 568544
650 4 $a Nosocomial infections. $3 833068
650 4 $a Public health. $3 534748
650 4 $a Pathology. $3 643180
655 7 $a Electronic books. $2 lcsh $3 542853
690 $a 0222
690 $a 0573
690 $a 0571
690 $a 0766
710 2 $a ProQuest Information and Learning Co. $3 783688
710 2 $a National University of Singapore (Singapore). $3 3352228
773 0 $t Dissertations Abstracts International $g 83-07B.
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=28832942 $z click for full text (PQDT)