東華大學圖書館 |

Language: English

Help

回圖書館首頁

手機版館藏查詢

Back

Switch To: Labeled | MARC Mode | ISBD

Linked to FindBook

Google Book

Amazon

博客來

Gait Adaptability with Healthy Aging and Parkinson's Disease.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Gait Adaptability with Healthy Aging and Parkinson's Disease./
Author:	Kuhman, Daniel.
Published:	Ann Arbor : ProQuest Dissertations & Theses, : 2021,
Description:	164 p.
Notes:	Source: Dissertations Abstracts International, Volume: 83-03, Section: B.
Contained By:	Dissertations Abstracts International83-03B.
Subject:	Biomechanics. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=28646328
ISBN:	9798544235286

Gait Adaptability with Healthy Aging and Parkinson's Disease.
Kuhman, Daniel.

Gait Adaptability with Healthy Aging and Parkinson's Disease. - Ann Arbor : ProQuest Dissertations & Theses, 2021 - 164 p.

Source: Dissertations Abstracts International, Volume: 83-03, Section: B.

Thesis (Ph.D.)--The University of Alabama at Birmingham, 2021.

This item must not be sold to any third party vendors.

Human locomotion often occurs through environments with complex sets of external demands (e.g., obstacles, uneven surfaces, altered terrain, etc.). Fortunately, humans have developed locomotor systems capable of rapidly adapting gait patterns to navigate these environments. Advanced age and neurological disorders such as Parkinson's disease (PD) are associated with physiological changes that add to the complexity of locomotion - these individuals must not only adapt to changing environmental demands, but also to changes in internal function (e.g., reduced muscle strength, dysfunctional sensorimotor integration). While there is a growing body of literature indicating that healthy older adults maintain adaptability, less is known about the effects of PD on this gait feature. This dissertation used a variety of experimental and analytical approaches to describe the effects of both healthy aging and PD on gait adaptability. We first compared joint-level kinetics between healthy older adults and PD patients walking at their self-selected comfortable and maximal speeds. We found that healthy older adults, but not PD patients, adapted joint-level kinetics to reach maximal walking speeds and noted that inability to appropriately adapt mechanics may limit the extent to which individuals with PD can speed up. We then supported these findings in a separate cohort completing a more controlled experimental protocol where individuals walked at a range of matched rather than self-selected speeds. In a third study, we confirmed high levels of gait adaptability with healthy aging by showing comparable rates of kinematic adaptation to split-belt treadmill walking under both normal and sensory-disrupted conditions in younger and older adults. Combined, results from this dissertation confirm that gait adaptability is maintained with healthy aging but not PD. Loss of gait adaptability has important functional consequences, including a reduced community ambulation and mobility. These results have important clinical implications. First, interventions aimed at reducing the extent to which healthy older adults adapt joint-level kinetics should consider that age-related adaptations are beneficial rather than detrimental in nature. Second, our results suggest that gait adaptability should be treated as target of interventions for individuals with PD.

ISBN: 9798544235286Subjects--Topical Terms:

548685
Biomechanics.
Subjects--Index Terms:

Biomechanics

Gait Adaptability with Healthy Aging and Parkinson's Disease.
LDR:03543nmm a2200385 4500 001 2351912
005 20221111113712.5
008 241004s2021 ||||||||||||||||| ||eng d
020 $a 9798544235286
035 $a (MiAaPQ)AAI28646328
035 $a AAI28646328
040 $a MiAaPQ $c MiAaPQ
100 1 $a Kuhman, Daniel. $3 3691506
245 1 0 $a Gait Adaptability with Healthy Aging and Parkinson's Disease.
260 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2021
300 $a 164 p.
500 $a Source: Dissertations Abstracts International, Volume: 83-03, Section: B.
500 $a Advisor: Hurt, Christopher P.
502 $a Thesis (Ph.D.)--The University of Alabama at Birmingham, 2021.
506 $a This item must not be sold to any third party vendors.
520 $a Human locomotion often occurs through environments with complex sets of external demands (e.g., obstacles, uneven surfaces, altered terrain, etc.). Fortunately, humans have developed locomotor systems capable of rapidly adapting gait patterns to navigate these environments. Advanced age and neurological disorders such as Parkinson's disease (PD) are associated with physiological changes that add to the complexity of locomotion - these individuals must not only adapt to changing environmental demands, but also to changes in internal function (e.g., reduced muscle strength, dysfunctional sensorimotor integration). While there is a growing body of literature indicating that healthy older adults maintain adaptability, less is known about the effects of PD on this gait feature. This dissertation used a variety of experimental and analytical approaches to describe the effects of both healthy aging and PD on gait adaptability. We first compared joint-level kinetics between healthy older adults and PD patients walking at their self-selected comfortable and maximal speeds. We found that healthy older adults, but not PD patients, adapted joint-level kinetics to reach maximal walking speeds and noted that inability to appropriately adapt mechanics may limit the extent to which individuals with PD can speed up. We then supported these findings in a separate cohort completing a more controlled experimental protocol where individuals walked at a range of matched rather than self-selected speeds. In a third study, we confirmed high levels of gait adaptability with healthy aging by showing comparable rates of kinematic adaptation to split-belt treadmill walking under both normal and sensory-disrupted conditions in younger and older adults. Combined, results from this dissertation confirm that gait adaptability is maintained with healthy aging but not PD. Loss of gait adaptability has important functional consequences, including a reduced community ambulation and mobility. These results have important clinical implications. First, interventions aimed at reducing the extent to which healthy older adults adapt joint-level kinetics should consider that age-related adaptations are beneficial rather than detrimental in nature. Second, our results suggest that gait adaptability should be treated as target of interventions for individuals with PD.
590 $a School code: 0005.
650 4 $a Biomechanics. $3 548685
650 4 $a Neurosciences. $3 588700
650 4 $a Kinesiology. $3 517627
650 4 $a Ankle. $3 3563106
650 4 $a Enrollments. $3 3562827
650 4 $a Exercise. $3 532868
650 4 $a Physical fitness. $3 522279
650 4 $a Adaptability. $3 3683626
650 4 $a Intervention. $3 3435307
650 4 $a Symmetry. $3 536815
650 4 $a Adaptation. $3 3562958
650 4 $a Ratios. $3 3561161
650 4 $a Older people. $3 761975
650 4 $a Orthopedics. $3 705991
650 4 $a Cognitive ability. $3 3560491
650 4 $a Feedback. $3 677181
650 4 $a Asymmetry. $3 3562922
650 4 $a Young adults. $3 598212
650 4 $a Cameras. $3 524039
650 4 $a Age. $3 1486010
650 4 $a Parkinsons disease. $3 3562685
650 4 $a Neurological disorders. $3 3684713
650 4 $a Participation. $3 1555180
650 4 $a Aging. $3 543123
650 4 $a Kinetics. $3 717752
650 4 $a Joint surgery. $3 3691469
650 4 $a Variance analysis. $3 3544969
653 $a Biomechanics
653 $a Gait analysis
653 $a Locomotion
653 $a Motor adaptation
653 $a Motor flexibility
690 $a 0648
690 $a 0317
690 $a 0575
690 $a 0493
710 2 $a The University of Alabama at Birmingham. $b Public Health. $3 3543709
773 0 $t Dissertations Abstracts International $g 83-03B.
790 $a 0005
791 $a Ph.D.
792 $a 2021
793 $a English
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=28646328