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Hematopoietic stem cells = keystone of tissue development and regenerative medicine /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Hematopoietic stem cells/ edited by Meng Zhao, Pengxu Qian.
Reminder of title:	keystone of tissue development and regenerative medicine /
other author:	Zhao, Meng.
Published:	Singapore :Springer Nature Singapore : : 2023.,
Description:	xv, 210 p. :ill., digital ;24 cm.
[NT 15003449]:	Chapter 1. Hematopoietic Stem Cell Development in Mammalian Embryos -- Chapter 2. Hematopoietic Stem Cells and Their Bone Marrow Niches -- Chapter 3. Emerging Roles of Epigenetic Regulators in Maintaining Hematopoietic Stem Cell Homeostasis -- Chapter 4. Metabolism in Hematopoiesis and Its Malignancy -- Chapter 5. The Origin of Clonal Hematopoiesis and Its Implication in Human Diseases -- Chapter 6. Ex vivo Expansion and Homing of Human Cord Blood Hematopoietic Stem Cells -- Chapter 7. N6-methyladenosine RNA Modification in Normal and Malignant Hematopoiesis -- Chapter 8. Immune System Influence on Hematopoietic Stem Cells and Leukemia Development -- Chapter 9. Learning from Zebrafish Hematopoiesis -- Chapter 10. Multi-lineage Differentiation from Hematopoietic Stem Cells -- Chapter 11. Gene Editing in Hematopoietic Stem Cells -- Chapter 12. Aging, Causes and Rejuvenation of Hematopoietic Stem Cells.
Contained By:	Springer Nature eBook
Subject:	Hematopoietic stem cells. -
Online resource:	https://doi.org/10.1007/978-981-99-7471-9
ISBN:	9789819974719

Hematopoietic stem cells = keystone of tissue development and regenerative medicine /
Hematopoietic stem cellskeystone of tissue development and regenerative medicine /[electronic resource] :edited by Meng Zhao, Pengxu Qian. - Singapore :Springer Nature Singapore :2023. - xv, 210 p. :ill., digital ;24 cm. - Advances in experimental medicine and biology,v. 14422214-8019 ;. - Advances in experimental medicine and biology ;v. 1442..

Chapter 1. Hematopoietic Stem Cell Development in Mammalian Embryos -- Chapter 2. Hematopoietic Stem Cells and Their Bone Marrow Niches -- Chapter 3. Emerging Roles of Epigenetic Regulators in Maintaining Hematopoietic Stem Cell Homeostasis -- Chapter 4. Metabolism in Hematopoiesis and Its Malignancy -- Chapter 5. The Origin of Clonal Hematopoiesis and Its Implication in Human Diseases -- Chapter 6. Ex vivo Expansion and Homing of Human Cord Blood Hematopoietic Stem Cells -- Chapter 7. N6-methyladenosine RNA Modification in Normal and Malignant Hematopoiesis -- Chapter 8. Immune System Influence on Hematopoietic Stem Cells and Leukemia Development -- Chapter 9. Learning from Zebrafish Hematopoiesis -- Chapter 10. Multi-lineage Differentiation from Hematopoietic Stem Cells -- Chapter 11. Gene Editing in Hematopoietic Stem Cells -- Chapter 12. Aging, Causes and Rejuvenation of Hematopoietic Stem Cells.

This book renders a comprehensive understanding of hematopoietic stem cells (HSCs) from their embryonic development through adult maintenance to aging, in the studies conducted in zebrafish and mammals. Hematopoiesis provides a paradigm for understanding the development, maintenance, regeneration, aging and malignant transformation of mammalian organs. Sitting at the apex of the hematopoiesis hierarchy tree, HSCs orchestrate their proliferation, self-renewal, and differentiation to produce all the blood cell lineages throughout life, which represents the best example for somatic stem cell studies. In this book, key regulatory mechanisms for HSC self-renewal and differentiation are overviewed in an array of fields including epigenetics, metabolism and microenvironment regulation. It also highlights the HSC heterogeneity and clonal dynamics from the recent advanced single-cell technologies. This book elaborates on the research history of HSC studies and reveals how the insights from HSC studies shed light on their clinic application. It presents great value from the bench to the clinic.

ISBN: 9789819974719

Standard No.: 10.1007/978-981-99-7471-9doiSubjects--Topical Terms:

600616
Hematopoietic stem cells.

LC Class. No.: QH588.S83

Dewey Class. No.: 616.02774

Hematopoietic stem cells = keystone of tissue development and regenerative medicine /
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245 0 0 $a Hematopoietic stem cells $h [electronic resource] : $b keystone of tissue development and regenerative medicine / $c edited by Meng Zhao, Pengxu Qian.
260 $a Singapore : $b Springer Nature Singapore : $b Imprint: Springer, $c 2023.
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490 1 $a Advances in experimental medicine and biology, $x 2214-8019 ; $v v. 1442
505 0 $a Chapter 1. Hematopoietic Stem Cell Development in Mammalian Embryos -- Chapter 2. Hematopoietic Stem Cells and Their Bone Marrow Niches -- Chapter 3. Emerging Roles of Epigenetic Regulators in Maintaining Hematopoietic Stem Cell Homeostasis -- Chapter 4. Metabolism in Hematopoiesis and Its Malignancy -- Chapter 5. The Origin of Clonal Hematopoiesis and Its Implication in Human Diseases -- Chapter 6. Ex vivo Expansion and Homing of Human Cord Blood Hematopoietic Stem Cells -- Chapter 7. N6-methyladenosine RNA Modification in Normal and Malignant Hematopoiesis -- Chapter 8. Immune System Influence on Hematopoietic Stem Cells and Leukemia Development -- Chapter 9. Learning from Zebrafish Hematopoiesis -- Chapter 10. Multi-lineage Differentiation from Hematopoietic Stem Cells -- Chapter 11. Gene Editing in Hematopoietic Stem Cells -- Chapter 12. Aging, Causes and Rejuvenation of Hematopoietic Stem Cells.
520 $a This book renders a comprehensive understanding of hematopoietic stem cells (HSCs) from their embryonic development through adult maintenance to aging, in the studies conducted in zebrafish and mammals. Hematopoiesis provides a paradigm for understanding the development, maintenance, regeneration, aging and malignant transformation of mammalian organs. Sitting at the apex of the hematopoiesis hierarchy tree, HSCs orchestrate their proliferation, self-renewal, and differentiation to produce all the blood cell lineages throughout life, which represents the best example for somatic stem cell studies. In this book, key regulatory mechanisms for HSC self-renewal and differentiation are overviewed in an array of fields including epigenetics, metabolism and microenvironment regulation. It also highlights the HSC heterogeneity and clonal dynamics from the recent advanced single-cell technologies. This book elaborates on the research history of HSC studies and reveals how the insights from HSC studies shed light on their clinic application. It presents great value from the bench to the clinic.
650 0 $a Hematopoietic stem cells. $3 600616
650 1 4 $a Biomedical Research. $3 851895
650 2 4 $a Stem Cell Biology. $3 3594097
650 2 4 $a Developmental Biology and Stem Cells. $3 3531341
700 1 $a Zhao, Meng. $3 1044024
700 1 $a Qian, Pengxu. $3 3672066
710 2 $a SpringerLink (Online service) $3 836513
773 0 $t Springer Nature eBook
830 0 $a Advances in experimental medicine and biology ; $v v. 1442. $3 3672067
856 4 0 $u https://doi.org/10.1007/978-981-99-7471-9
950 $a Biomedical and Life Sciences (SpringerNature-11642)