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Saito, Yuki.

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Multistep continuous flow synthesis of fine chemicals with heterogeneous catalysts

Record Type:	Electronic resources : Monograph/item
Title/Author:	Multistep continuous flow synthesis of fine chemicals with heterogeneous catalysts/ by Yuki Saito.
Author:	Saito, Yuki.
Published:	Singapore :Springer Nature Singapore : : 2023.,
Description:	xviii, 172 p. :ill., digital ;24 cm.
[NT 15003449]:	1. Introduction and Strategy -- 2. Synthesis of Nitro-containing Compounds through Multistep Continuous-flow with Heterogeneous Catalysts -- 3. Polysilane-Supported Pd Catalysts for Continuous-flow Hydrogenations -- 4. Anion Exchange Resins as Catalysts for Direct Aldol-type Reactions of Ketones, Esters and Nitriles under Continuous-flow -- 5. Multistep Continuous-flow Synthesis of APIs Based on Aldol-hydrogenation Strategy -- 6. Summary -- 7. Experimental Section.
Contained By:	Springer Nature eBook
Subject:	Organic compounds - Synthesis. -
Online resource:	https://doi.org/10.1007/978-981-19-7258-4
ISBN:	9789811972584

Multistep continuous flow synthesis of fine chemicals with heterogeneous catalysts
Saito, Yuki.

Multistep continuous flow synthesis of fine chemicals with heterogeneous catalysts[electronic resource] /by Yuki Saito. - Singapore :Springer Nature Singapore :2023. - xviii, 172 p. :ill., digital ;24 cm. - Springer theses,2190-5061. - Springer theses..

1. Introduction and Strategy -- 2. Synthesis of Nitro-containing Compounds through Multistep Continuous-flow with Heterogeneous Catalysts -- 3. Polysilane-Supported Pd Catalysts for Continuous-flow Hydrogenations -- 4. Anion Exchange Resins as Catalysts for Direct Aldol-type Reactions of Ketones, Esters and Nitriles under Continuous-flow -- 5. Multistep Continuous-flow Synthesis of APIs Based on Aldol-hydrogenation Strategy -- 6. Summary -- 7. Experimental Section.

This book describes the development of two kinds of continuous-flow transformation using heterogeneous catalysts, and explains how they can be applied in the multistep synthesis of active pharmaceutical ingredients. It demonstrates and proves that fine chemicals can be synthesized under continuous-flow conditions using heterogeneous catalysis alone. Importantly, the book also proposes a general concept and strategy for achieving multistep flow synthesis and developing heterogeneous catalysts, and shows that commercially available anion exchange resin can be used as a water-tolerant strong base catalyst for various types of continuous-flow aldol-type reaction. Reviewing the state of the art in heterogeneous catalysis in flow chemistry - a "hot topic" and rapidly developing area of organic synthesis - the book will provide readers with a deeper understanding of fine chemical flow synthesis and its future prospects.

ISBN: 9789811972584

Standard No.: 10.1007/978-981-19-7258-4doiSubjects--Topical Terms:

560477
Organic compounds
--Synthesis.

LC Class. No.: QD262

Dewey Class. No.: 547.2

Multistep continuous flow synthesis of fine chemicals with heterogeneous catalysts
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505 0 $a 1. Introduction and Strategy -- 2. Synthesis of Nitro-containing Compounds through Multistep Continuous-flow with Heterogeneous Catalysts -- 3. Polysilane-Supported Pd Catalysts for Continuous-flow Hydrogenations -- 4. Anion Exchange Resins as Catalysts for Direct Aldol-type Reactions of Ketones, Esters and Nitriles under Continuous-flow -- 5. Multistep Continuous-flow Synthesis of APIs Based on Aldol-hydrogenation Strategy -- 6. Summary -- 7. Experimental Section.
520 $a This book describes the development of two kinds of continuous-flow transformation using heterogeneous catalysts, and explains how they can be applied in the multistep synthesis of active pharmaceutical ingredients. It demonstrates and proves that fine chemicals can be synthesized under continuous-flow conditions using heterogeneous catalysis alone. Importantly, the book also proposes a general concept and strategy for achieving multistep flow synthesis and developing heterogeneous catalysts, and shows that commercially available anion exchange resin can be used as a water-tolerant strong base catalyst for various types of continuous-flow aldol-type reaction. Reviewing the state of the art in heterogeneous catalysis in flow chemistry - a "hot topic" and rapidly developing area of organic synthesis - the book will provide readers with a deeper understanding of fine chemical flow synthesis and its future prospects.
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