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Drug target selection and validation

Scotti, Marcus T.

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Drug target selection and validation

Record Type:	Electronic resources : Monograph/item
Title/Author:	Drug target selection and validation/ edited by Marcus T. Scotti, Carolina L. Bellera.
other author:	Scotti, Marcus T.
Published:	Cham :Springer International Publishing : : 2022.,
Description:	xv, 257 p. :ill. (chiefly col.), digital ;24 cm.
[NT 15003449]:	Drug discovery paradigms: target-based drug discovery -- Drug discovery paradigms: phenotypic-based drug discovery -- Target Identification Approaches in Drug Discovery -- Introduction to target validation -- Structure-based binding pocket detection and druggability assessment -- Network-Based Target Identification -- The Current State of Precision Medicine and Targeted-Cancer Therapies - Where are We? -- Metabolic Control Analysis for drug target selection against human diseases -- Progress on open chemoinformatic tools for drug discovery.
Contained By:	Springer Nature eBook
Subject:	Drug development - Computer simulation. -
Online resource:	https://doi.org/10.1007/978-3-030-95895-4
ISBN:	9783030958954

Drug target selection and validation
Drug target selection and validation[electronic resource] /edited by Marcus T. Scotti, Carolina L. Bellera. - Cham :Springer International Publishing :2022. - xv, 257 p. :ill. (chiefly col.), digital ;24 cm. - Computer-aided drug discovery and design,2730-5465. - Computer-aided drug discovery and design..

Drug discovery paradigms: target-based drug discovery -- Drug discovery paradigms: phenotypic-based drug discovery -- Target Identification Approaches in Drug Discovery -- Introduction to target validation -- Structure-based binding pocket detection and druggability assessment -- Network-Based Target Identification -- The Current State of Precision Medicine and Targeted-Cancer Therapies - Where are We? -- Metabolic Control Analysis for drug target selection against human diseases -- Progress on open chemoinformatic tools for drug discovery.

The first book in the newly created book series, Computer-Aided Drug Discovery and Design, focuses on the computational aspects of early drug discovery, drug target identification, and validation. It revises current classical paradigms in target and phenotypic-based drug design with still ingrained approximations and concepts and discusses the research in the new network approach concept that include kinetic selectivity and metabolic analysis. Many often-overlooked approximations and concepts in drug discovery are fully covered. Drug Target Selection and Validation includes both introductory sections and research-based sections to be of use to both students and research scientists in drug discovery, design, kinetics and metabolic analysis. Pharmaceutical scientists, pharmaceutics, drug developers, pharmacologists, biomedical researchers in computer science, medicinal chemists, and precision medicine developers benefit from the information provided. The book concludes with a chapter on chemical and structural databases.

ISBN: 9783030958954

Standard No.: 10.1007/978-3-030-95895-4doiSubjects--Topical Terms:

768310
Drug development
--Computer simulation.

LC Class. No.: RM301.25

Dewey Class. No.: 615.190113

Drug target selection and validation
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245 0 0 $a Drug target selection and validation $h [electronic resource] / $c edited by Marcus T. Scotti, Carolina L. Bellera.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2022.
300 $a xv, 257 p. : $b ill. (chiefly col.), digital ; $c 24 cm.
490 1 $a Computer-aided drug discovery and design, $x 2730-5465
505 0 $a Drug discovery paradigms: target-based drug discovery -- Drug discovery paradigms: phenotypic-based drug discovery -- Target Identification Approaches in Drug Discovery -- Introduction to target validation -- Structure-based binding pocket detection and druggability assessment -- Network-Based Target Identification -- The Current State of Precision Medicine and Targeted-Cancer Therapies - Where are We? -- Metabolic Control Analysis for drug target selection against human diseases -- Progress on open chemoinformatic tools for drug discovery.
520 $a The first book in the newly created book series, Computer-Aided Drug Discovery and Design, focuses on the computational aspects of early drug discovery, drug target identification, and validation. It revises current classical paradigms in target and phenotypic-based drug design with still ingrained approximations and concepts and discusses the research in the new network approach concept that include kinetic selectivity and metabolic analysis. Many often-overlooked approximations and concepts in drug discovery are fully covered. Drug Target Selection and Validation includes both introductory sections and research-based sections to be of use to both students and research scientists in drug discovery, design, kinetics and metabolic analysis. Pharmaceutical scientists, pharmaceutics, drug developers, pharmacologists, biomedical researchers in computer science, medicinal chemists, and precision medicine developers benefit from the information provided. The book concludes with a chapter on chemical and structural databases.
650 0 $a Drug development $x Computer simulation. $3 768310
650 0 $a Drugs $x Computer-aided design. $3 3490637
650 1 4 $a Pharmacology. $3 634543
650 2 4 $a Pharmaceutics. $3 3538434
650 2 4 $a Structure-Based Drug Design. $3 3538435
650 2 4 $a Medicinal Chemistry. $3 892420
650 2 4 $a Molecular Biology. $3 600567
700 1 $a Scotti, Marcus T. $3 3597418
700 1 $a Bellera, Carolina L. $3 3597419
710 2 $a SpringerLink (Online service) $3 836513
773 0 $t Springer Nature eBook
830 0 $a Computer-aided drug discovery and design. $3 3597420
856 4 0 $u https://doi.org/10.1007/978-3-030-95895-4
950 $a Biomedical and Life Sciences (SpringerNature-11642)