東華大學圖書館 |

Language: English

Help

回圖書館首頁

手機版館藏查詢

Back

Switch To: Labeled | MARC Mode | ISBD

Gadd45 stress sensor genes

Zaidi, M. Raza.

Linked to FindBook

Google Book

Amazon

博客來

Gadd45 stress sensor genes

Record Type:	Electronic resources : Monograph/item
Title/Author:	Gadd45 stress sensor genes/ edited by M. Raza Zaidi, Dan A. Liebermann.
other author:	Zaidi, M. Raza.
Published:	Cham :Springer International Publishing : : 2022.,
Description:	ix, 153 p. :ill., digital ;24 cm.
[NT 15003449]:	GADD45 in Stress Signaling, Cell Cycle Control, and Apoptosis -- GADD45 in Development and Cancer -- GADD45 in Normal Hematopoiesis and Leukemia -- GADD45 in DNA Methylation and DNA Repair -- GADD45 Proteins in Immunity -- GADD45 in Liver Function and Cancer -- GADD45 in Pre-Eclampsia -- GADD45 in Senescence -- GADD45 in Neuronal Development, Function, and Injury -- Index.
Contained By:	Springer Nature eBook
Subject:	Human molecular genetics. -
Online resource:	https://doi.org/10.1007/978-3-030-94804-7
ISBN:	9783030948047

Gadd45 stress sensor genes
Gadd45 stress sensor genes[electronic resource] /edited by M. Raza Zaidi, Dan A. Liebermann. - Second edition. - Cham :Springer International Publishing :2022. - ix, 153 p. :ill., digital ;24 cm. - Advances in experimental medicine and biology,v. 13602214-8019 ;. - Advances in experimental medicine and biology ;v. 1360..

GADD45 in Stress Signaling, Cell Cycle Control, and Apoptosis -- GADD45 in Development and Cancer -- GADD45 in Normal Hematopoiesis and Leukemia -- GADD45 in DNA Methylation and DNA Repair -- GADD45 Proteins in Immunity -- GADD45 in Liver Function and Cancer -- GADD45 in Pre-Eclampsia -- GADD45 in Senescence -- GADD45 in Neuronal Development, Function, and Injury -- Index.

This second edition is fully updated throughout and covers the emerging evidence that indicates that the Gadd45 family of proteins plays a unique and critical role as sensors of stress, including genotoxic, physiological, and oncogenic stress. It sheds light on the complex cellular stress response, encompassing myriad molecular pathways with a plethora of regulators and effectors. The GADD45 stress response genes encode small (18 kd) nuclear/cytoplasmic proteins. These genes are rapidly induced by a wide variety of endogenous and exogenous stress stimuli. Despite marked similarities, Gadd45 genes are regulated differentially and exhibit functional diversity. Gadd45 proteins respond to physiological and oncogenic stress, and are implicated in cell cycle arrest, DNA demethylation and repair, apoptosis, cell survival, genomic stability, and inflammation. The purpose of this book is to provide a comprehensive overview of the unique global role that Gadd45 proteins play as stress sensors and the molecular pathways involved.

ISBN: 9783030948047

Standard No.: 10.1007/978-3-030-94804-7doiSubjects--Topical Terms:

740999
Human molecular genetics.

LC Class. No.: QH431

Dewey Class. No.: 11.01816

Gadd45 stress sensor genes
LDR:02549nmm a2200373 a 4500 001 2299640
003 DE-He213
005 20220503232413.0
006 m d
007 cr nn 008maaau
008 230324s2022 sz s 0 eng d
020 $a 9783030948047 $q (electronic bk.)
020 $a 9783030948030 $q (paper)
024 7 $a 10.1007/978-3-030-94804-7 $2 doi
035 $a 978-3-030-94804-7
040 $a GP $c GP
041 0 $a eng
050 4 $a QH431
072 7 $a MFN $2 bicssc
072 7 $a MFN $2 bicssc
072 7 $a MED107000 $2 bisacsh
072 7 $a MFN $2 thema
072 7 $a MFN $2 thema
082 0 4 $a 11.01816 $2 23
090 $a QH431 $b .G123 2022
245 0 0 $a Gadd45 stress sensor genes $h [electronic resource] / $c edited by M. Raza Zaidi, Dan A. Liebermann.
250 $a Second edition.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2022.
300 $a ix, 153 p. : $b ill., digital ; $c 24 cm.
490 1 $a Advances in experimental medicine and biology, $x 2214-8019 ; $v v. 1360
505 0 $a GADD45 in Stress Signaling, Cell Cycle Control, and Apoptosis -- GADD45 in Development and Cancer -- GADD45 in Normal Hematopoiesis and Leukemia -- GADD45 in DNA Methylation and DNA Repair -- GADD45 Proteins in Immunity -- GADD45 in Liver Function and Cancer -- GADD45 in Pre-Eclampsia -- GADD45 in Senescence -- GADD45 in Neuronal Development, Function, and Injury -- Index.
520 $a This second edition is fully updated throughout and covers the emerging evidence that indicates that the Gadd45 family of proteins plays a unique and critical role as sensors of stress, including genotoxic, physiological, and oncogenic stress. It sheds light on the complex cellular stress response, encompassing myriad molecular pathways with a plethora of regulators and effectors. The GADD45 stress response genes encode small (18 kd) nuclear/cytoplasmic proteins. These genes are rapidly induced by a wide variety of endogenous and exogenous stress stimuli. Despite marked similarities, Gadd45 genes are regulated differentially and exhibit functional diversity. Gadd45 proteins respond to physiological and oncogenic stress, and are implicated in cell cycle arrest, DNA demethylation and repair, apoptosis, cell survival, genomic stability, and inflammation. The purpose of this book is to provide a comprehensive overview of the unique global role that Gadd45 proteins play as stress sensors and the molecular pathways involved.
650 0 $a Human molecular genetics. $3 740999
650 0 $a Protein-protein interactions. $3 767666
650 0 $a Cellular signal transduction. $3 600648
650 1 4 $a Medical Genetics. $3 3531302
650 2 4 $a Microbial Genetics. $3 3531348
700 1 $a Zaidi, M. Raza. $3 3597322
700 1 $a Liebermann, Dan A. $3 3597323
710 2 $a SpringerLink (Online service) $3 836513
773 0 $t Springer Nature eBook
830 0 $a Advances in experimental medicine and biology ; $v v. 1360. $3 3597324
856 4 0 $u https://doi.org/10.1007/978-3-030-94804-7
950 $a Biomedical and Life Sciences (SpringerNature-11642)