東華大學圖書館 |

Language: English

Help

回圖書館首頁

手機版館藏查詢

Back

Switch To: Labeled | MARC Mode | ISBD

Biology at the Microscale: New Techn...

Alvarez-Garcia, Yasmin Rosaura.

Linked to FindBook

Google Book

Amazon

博客來

Biology at the Microscale: New Techniques for Cellular Experimentation.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Biology at the Microscale: New Techniques for Cellular Experimentation./
Author:	Alvarez-Garcia, Yasmin Rosaura.
Published:	Ann Arbor : ProQuest Dissertations & Theses, : 2020,
Description:	195 p.
Notes:	Source: Dissertations Abstracts International, Volume: 81-11, Section: B.
Contained By:	Dissertations Abstracts International81-11B.
Subject:	Biomedical engineering. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=27962854
ISBN:	9798645443665

Biology at the Microscale: New Techniques for Cellular Experimentation.
Alvarez-Garcia, Yasmin Rosaura.

Biology at the Microscale: New Techniques for Cellular Experimentation. - Ann Arbor : ProQuest Dissertations & Theses, 2020 - 195 p.

Source: Dissertations Abstracts International, Volume: 81-11, Section: B.

Thesis (Ph.D.)--The University of Wisconsin - Madison, 2020.

This item must not be sold to any third party vendors.

Microfluidic approaches offer the ability to accurately emulate diverse microenvironments, while often outpacing traditional macro-level approaches in versatility, scalability and efficiency of production. Nevertheless, the uptake of such methods in biological research has been hampered by the absence of microfluidic systems that are specifically adapted to the needs of given investigations. This thesis attempts to show how microfluidic engineering can be more closely harnessed to the explicit needs of such objectives. Presented here is an array of systems that function on the microscale, and have been designed, fabricated, and tested to meet the needs of discrete biological questions. A microdevice is proposed that serves as a multi-culture platform for assessing multi-cell-type interactions, and a widely-applicable adhesive tool for the fabrication of such devices is tested for broader use. A novel microfluidic system for experimenting on fungal spore adhesion is discussed, and used to assay potential biocontrol agents of vital importance to agricultural production. Finally, the development of a cell immobilization technology is detailed, with an emphasis on how functioning at the microscale lends distinct advantages to the storage and imaging of rare samples. Taken overall, these technologies are intended to show that sensitivity on the engineering level can help bridge the gap between microscale tools and the biological investigations in which they offer so much promise.

ISBN: 9798645443665Subjects--Topical Terms:

535387
Biomedical engineering.
Subjects--Index Terms:

Cell immobilization

Biology at the Microscale: New Techniques for Cellular Experimentation.
LDR:02716nmm a2200385 4500 001 2267027
005 20200623063231.5
008 220629s2020 ||||||||||||||||| ||eng d
020 $a 9798645443665
035 $a (MiAaPQ)AAI27962854
035 $a AAI27962854
040 $a MiAaPQ $c MiAaPQ
100 1 $a Alvarez-Garcia, Yasmin Rosaura. $3 3544266
245 1 0 $a Biology at the Microscale: New Techniques for Cellular Experimentation.
260 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2020
300 $a 195 p.
500 $a Source: Dissertations Abstracts International, Volume: 81-11, Section: B.
500 $a Advisor: Beebe, David J.
502 $a Thesis (Ph.D.)--The University of Wisconsin - Madison, 2020.
506 $a This item must not be sold to any third party vendors.
520 $a Microfluidic approaches offer the ability to accurately emulate diverse microenvironments, while often outpacing traditional macro-level approaches in versatility, scalability and efficiency of production. Nevertheless, the uptake of such methods in biological research has been hampered by the absence of microfluidic systems that are specifically adapted to the needs of given investigations. This thesis attempts to show how microfluidic engineering can be more closely harnessed to the explicit needs of such objectives. Presented here is an array of systems that function on the microscale, and have been designed, fabricated, and tested to meet the needs of discrete biological questions. A microdevice is proposed that serves as a multi-culture platform for assessing multi-cell-type interactions, and a widely-applicable adhesive tool for the fabrication of such devices is tested for broader use. A novel microfluidic system for experimenting on fungal spore adhesion is discussed, and used to assay potential biocontrol agents of vital importance to agricultural production. Finally, the development of a cell immobilization technology is detailed, with an emphasis on how functioning at the microscale lends distinct advantages to the storage and imaging of rare samples. Taken overall, these technologies are intended to show that sensitivity on the engineering level can help bridge the gap between microscale tools and the biological investigations in which they offer so much promise.
590 $a School code: 0262.
650 4 $a Biomedical engineering. $3 535387
650 4 $a Microbiology. $3 536250
650 4 $a Cellular biology. $3 3172791
653 $a Cell immobilization
653 $a Fungal spore adhesion
653 $a Microfluidics
653 $a Multi-cell type interactions
653 $a Multi-culture
653 $a Razor printing
690 $a 0541
690 $a 0410
690 $a 0379
710 2 $a The University of Wisconsin - Madison. $b Chemistry. $3 2049906
773 0 $t Dissertations Abstracts International $g 81-11B.
790 $a 0262
791 $a Ph.D.
792 $a 2020
793 $a English
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=27962854