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Acute Inflammatory Response as a Med...

Hunschede, Sascha .

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Acute Inflammatory Response as a Mediator of the Effects of High-intensity Exercise on Appetite and Food Intake in Boys.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Acute Inflammatory Response as a Mediator of the Effects of High-intensity Exercise on Appetite and Food Intake in Boys./
作者:	Hunschede, Sascha .
出版者:	Ann Arbor : ProQuest Dissertations & Theses, : 2019,
面頁冊數:	215 p.
附註:	Source: Dissertations Abstracts International, Volume: 81-06, Section: B.
Contained By:	Dissertations Abstracts International81-06B.
標題:	Nutrition. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=27539737
ISBN:	9781392756980

Acute Inflammatory Response as a Mediator of the Effects of High-intensity Exercise on Appetite and Food Intake in Boys.
Hunschede, Sascha .

Acute Inflammatory Response as a Mediator of the Effects of High-intensity Exercise on Appetite and Food Intake in Boys. - Ann Arbor : ProQuest Dissertations & Theses, 2019 - 215 p.

Source: Dissertations Abstracts International, Volume: 81-06, Section: B.

Thesis (Ph.D.)--University of Toronto (Canada), 2019.

This item must not be sold to any third party vendors.

The effect of high-intensity exercise (HIEX) and the mechanism by which it suppresses appetite and food intake (FI) is not well understood. The hypothesis of this research was that inflammation during and after HIEX plays a role. Three experiments were designed to investigate the hypothesis and to compare these mechanisms with the effects of macronutrient ingestion in male children. Experiment 1 investigated the effects of HIEX induced inflammatory- and stress biomarkers on appetite control in normal-weight (NW) and overweight/obese boys. HIEX resulted in reduced appetite that correlated with an increase in plasma concentration of IL-6 with no effect of body-weight. However, while a role for IL-6 in the response can be suggested, the suppression of appetite could have been mediated by the associated decrease in active ghrelin and/or increase in cortisol. Experiment 2 further examined the role of IL-6 in exercise-induced anorexia in NW children. HIEX reduced subjective appetite but not FI, increased IL-6 and cortisol and decreased active ghrelin and blood glucose. An independent role for IL-6 in appetite suppression was not supported. However, IL-6 response was associated with active ghrelin and cortisol, thus potentially mediating appetite via these interactions. Experiment 3 was a study of the role of IL-6 and TNF-α in satiety and appetite after consumption of glucose or protein beverage by boys. Neither affected an immediate response in plasma IL-6 and TNF-α concentrations. However, in the pooled data, mean levels of IL-6 were strongly correlated with later FI. Thus, this research provides support for further examination of the role of IL-6 in appetite control.

ISBN: 9781392756980Subjects--Topical Terms:

517777
Nutrition.
Subjects--Index Terms:

Appetite control

Acute Inflammatory Response as a Mediator of the Effects of High-intensity Exercise on Appetite and Food Intake in Boys.
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