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Progress in the chemistry of organic...

Kinghorn, A. Douglas.

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Progress in the chemistry of organic natural products.. Volume 115

Record Type:	Electronic resources : Monograph/item
Title/Author:	Progress in the chemistry of organic natural products./ edited by A. Douglas Kinghorn ... [et al.].
other author:	Kinghorn, A. Douglas.
Published:	Cham :Springer International Publishing : : 2021.,
Description:	vii, 203 p. :ill., digital ;24 cm.
[NT 15003449]:	Total Synthesis of Decanolides (Nonanolides) with a Special Focus on Olefin Metathesis -- From Plant to Patient: Thapsigargin -- Antileishmanial Activity of Lignans and Neolignans -- Cryptolepine as a Lead to new Antiprotozoal Agents -- Biologically Active Constituents from Plants of the Genus Xanthium.
Contained By:	Springer Nature eBook
Subject:	Chemistry, Organic. -
Online resource:	https://doi.org/10.1007/978-3-030-64853-4
ISBN:	9783030648534

Progress in the chemistry of organic natural products.. Volume 115
Progress in the chemistry of organic natural products.Volume 115[electronic resource] /edited by A. Douglas Kinghorn ... [et al.]. - Cham :Springer International Publishing :2021. - vii, 203 p. :ill., digital ;24 cm. - Progress in the chemistry of organic natural products,1152191-7043 ;. - Progress in the chemistry of organic natural products ;115..

Total Synthesis of Decanolides (Nonanolides) with a Special Focus on Olefin Metathesis -- From Plant to Patient: Thapsigargin -- Antileishmanial Activity of Lignans and Neolignans -- Cryptolepine as a Lead to new Antiprotozoal Agents -- Biologically Active Constituents from Plants of the Genus Xanthium.

This book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found primarily in fungi, frogs, and termites is presented. The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca2+ ATPase), which has potential as a lead compound to treat cancer. The third chapter covers the potential of various plant phenolic compounds for treating the tropical and sub-tropical infectious disease, leishmaniasis. In addition the volume presents recent advances related to the plant alkaloid, cryptolepine, which is of particular interest as a lead for the treatment of malaria, trypanosomiasis, and cancer.

ISBN: 9783030648534

Standard No.: 10.1007/978-3-030-64853-4doiSubjects--Topical Terms:

516206
Chemistry, Organic.

LC Class. No.: QD251 / .P764 2021

Dewey Class. No.: 547

Progress in the chemistry of organic natural products.. Volume 115
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300 $a vii, 203 p. : $b ill., digital ; $c 24 cm.
490 1 $a Progress in the chemistry of organic natural products, $x 2191-7043 ; $v 115
505 0 $a Total Synthesis of Decanolides (Nonanolides) with a Special Focus on Olefin Metathesis -- From Plant to Patient: Thapsigargin -- Antileishmanial Activity of Lignans and Neolignans -- Cryptolepine as a Lead to new Antiprotozoal Agents -- Biologically Active Constituents from Plants of the Genus Xanthium.
520 $a This book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found primarily in fungi, frogs, and termites is presented. The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca2+ ATPase), which has potential as a lead compound to treat cancer. The third chapter covers the potential of various plant phenolic compounds for treating the tropical and sub-tropical infectious disease, leishmaniasis. In addition the volume presents recent advances related to the plant alkaloid, cryptolepine, which is of particular interest as a lead for the treatment of malaria, trypanosomiasis, and cancer.
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