東華大學圖書館 |

語系: 繁體中文

說明(常見問題)

回圖書館首頁

手機版館藏查詢

登入

回首頁

切換: 標籤 | MARC模式 | ISBD

Prenatal Exposure to Perfluoroalkyl ...

Meng, Qi.

FindBook

Google Book

Amazon

博客來

Prenatal Exposure to Perfluoroalkyl Substances and Birth Outcomes; A Pooled Analysis in the Danish National Birth Cohort.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Prenatal Exposure to Perfluoroalkyl Substances and Birth Outcomes; A Pooled Analysis in the Danish National Birth Cohort./
作者:	Meng, Qi.
出版者:	Ann Arbor : ProQuest Dissertations & Theses, : 2018,
面頁冊數:	26 p.
附註:	Source: Masters Abstracts International, Volume: 57-05.
Contained By:	Masters Abstracts International57-05(E).
標題:	Public health. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10787918
ISBN:	9780355851854

Prenatal Exposure to Perfluoroalkyl Substances and Birth Outcomes; A Pooled Analysis in the Danish National Birth Cohort.
Meng, Qi.

Prenatal Exposure to Perfluoroalkyl Substances and Birth Outcomes; A Pooled Analysis in the Danish National Birth Cohort. - Ann Arbor : ProQuest Dissertations & Theses, 2018 - 26 p.

Source: Masters Abstracts International, Volume: 57-05.

Thesis (M.S.)--University of California, Los Angeles, 2018.

Perfluoroalkyl substances (PFASs) are widespread industrial pollutants that are extremely persistent in the environment. Animal studies have indicated that in-utero PFAS exposures can affect fetal growth, but findings from human studies are inconclusive. Few human studies have sufficient sample size to study the influence of PFASs on adverse birth outcomes. Here, we conducted a pooled analysis using data of 3,535 mothers and infant pairs using three sub-samples originating from the Danish National Birth Cohort (DNBC), and we evaluated the associations between prenatal PFASs exposures and birth outcomes. Maternal plasma concentrations of six types of PFASs in early pregnancy (around 8.7 gestational weeks) were studied. We found that each LN-ng/ml increase in PFOS, PFOA, PFNA and PFHpS was associated with a 65g, 51g, 52g or 56g decrease in birth weight. Moreover, we also found that prenatal PFOS, PFHpS, PFDA levels were associated with the risks for preterm birth (< 37 completed gestational week). Our findings strengthen the evidence that in-utero PFAS exposures may affect fetal growth. These findings raise concerns considering the ubiquitous contamination of PFASs in the environment. Public health strategies to prevent or lower PFASs exposures in pregnant women are needed.

ISBN: 9780355851854Subjects--Topical Terms:

534748
Public health.

Prenatal Exposure to Perfluoroalkyl Substances and Birth Outcomes; A Pooled Analysis in the Danish National Birth Cohort.
LDR:02242nmm a2200289 4500 001 2203164
005 20190528072651.5
008 201008s2018 ||||||||||||||||| ||eng d
020 $a 9780355851854
035 $a (MiAaPQ)AAI10787918
035 $a (MiAaPQ)ucla:16638
035 $a AAI10787918
040 $a MiAaPQ $c MiAaPQ
100 1 $a Meng, Qi. $3 3429953
245 1 0 $a Prenatal Exposure to Perfluoroalkyl Substances and Birth Outcomes; A Pooled Analysis in the Danish National Birth Cohort.
260 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2018
300 $a 26 p.
500 $a Source: Masters Abstracts International, Volume: 57-05.
500 $a Adviser: Beate Ritz.
502 $a Thesis (M.S.)--University of California, Los Angeles, 2018.
520 $a Perfluoroalkyl substances (PFASs) are widespread industrial pollutants that are extremely persistent in the environment. Animal studies have indicated that in-utero PFAS exposures can affect fetal growth, but findings from human studies are inconclusive. Few human studies have sufficient sample size to study the influence of PFASs on adverse birth outcomes. Here, we conducted a pooled analysis using data of 3,535 mothers and infant pairs using three sub-samples originating from the Danish National Birth Cohort (DNBC), and we evaluated the associations between prenatal PFASs exposures and birth outcomes. Maternal plasma concentrations of six types of PFASs in early pregnancy (around 8.7 gestational weeks) were studied. We found that each LN-ng/ml increase in PFOS, PFOA, PFNA and PFHpS was associated with a 65g, 51g, 52g or 56g decrease in birth weight. Moreover, we also found that prenatal PFOS, PFHpS, PFDA levels were associated with the risks for preterm birth (< 37 completed gestational week). Our findings strengthen the evidence that in-utero PFAS exposures may affect fetal growth. These findings raise concerns considering the ubiquitous contamination of PFASs in the environment. Public health strategies to prevent or lower PFASs exposures in pregnant women are needed.
590 $a School code: 0031.
650 4 $a Public health. $3 534748
690 $a 0573
710 2 $a University of California, Los Angeles. $b Epidemiology 0357. $3 2100278
773 0 $t Masters Abstracts International $g 57-05(E).
790 $a 0031
791 $a M.S.
792 $a 2018
793 $a English
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10787918