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Occupational Exposures and Subclinic...

Sack, Coralynn.

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Occupational Exposures and Subclinical Interstitial Lung Disease: The Mesa (Multi-Ethnic Study of Atherosclerosis) Air-Lung Study.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Occupational Exposures and Subclinical Interstitial Lung Disease: The Mesa (Multi-Ethnic Study of Atherosclerosis) Air-Lung Study./
Author:	Sack, Coralynn.
Published:	Ann Arbor : ProQuest Dissertations & Theses, : 2018,
Description:	46 p.
Notes:	Source: Masters Abstracts International, Volume: 57-05.
Contained By:	Masters Abstracts International57-05(E).
Subject:	Epidemiology. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10234542
ISBN:	9780355849318

Occupational Exposures and Subclinical Interstitial Lung Disease: The Mesa (Multi-Ethnic Study of Atherosclerosis) Air-Lung Study.
Sack, Coralynn.

Occupational Exposures and Subclinical Interstitial Lung Disease: The Mesa (Multi-Ethnic Study of Atherosclerosis) Air-Lung Study. - Ann Arbor : ProQuest Dissertations & Theses, 2018 - 46 p.

Source: Masters Abstracts International, Volume: 57-05.

Thesis (Master's)--University of Washington, 2018.

Rationale: The impact of a broad range of occupational exposures on subclinical interstitial lung disease (ILD) has not been studied.

ISBN: 9780355849318Subjects--Topical Terms:

568544
Epidemiology.

Occupational Exposures and Subclinical Interstitial Lung Disease: The Mesa (Multi-Ethnic Study of Atherosclerosis) Air-Lung Study.
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020 $a 9780355849318
035 $a (MiAaPQ)AAI10234542
035 $a (MiAaPQ)washington:15496
035 $a AAI10234542
040 $a MiAaPQ $c MiAaPQ
100 1 $a Sack, Coralynn. $3 3428667
245 1 0 $a Occupational Exposures and Subclinical Interstitial Lung Disease: The Mesa (Multi-Ethnic Study of Atherosclerosis) Air-Lung Study.
260 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2018
300 $a 46 p.
500 $a Source: Masters Abstracts International, Volume: 57-05.
500 $a Adviser: Joel D. Kaufman.
502 $a Thesis (Master's)--University of Washington, 2018.
520 $a Rationale: The impact of a broad range of occupational exposures on subclinical interstitial lung disease (ILD) has not been studied.
520 $a Objectives: To determine whether occupational exposures to vapors, gas, dust, and fumes (VGDF) are associated with high-attenuation areas (HAAs) and interstitial lung abnormalities (ILAs4), which are quantitative and qualitative computed tomography (CT)--based measurements of subclinical ILD, respectively.
520 $a Methods: We performed analyses of participants enrolled in MESA (Multi-Ethnic Study of Atherosclerosis), a population-based cohort aged 45--84 years at recruitment. HAA was measured at baseline and on serial cardiac CT scans in 5,702 participants. ILA was ascertained in a subset of 2,312 participants who underwent full-lung CT scanning at 10-year follow-up. Occupational exposures were assessed by self-reported VGDF exposure and by job-exposure matrix (JEM). Linear mixed models and logistic regression were used to determine whether occupational exposures were associated with log-transformed HAA and ILA. Models were adjusted for age, sex, race/ethnicity, education, employment status, tobacco use, and scanner technology.
520 $a Results: Each JEM score increment in VGDF exposure was associated with 2.64% greater HAA (95% confidence interval [CI], 1.23--4.19%). Self-reported vapors/gas exposure was associated with an increased odds of ILA among those currently employed (1.76-fold; 95% CI, 1.09--2.84) and those less than 65 years old (1.97-fold; 95% CI, 1.16--3.35). There was no consistent evidence that occupational exposures were associated with progression of HAA over the follow-up period.
520 $a Conclusions: JEM-assigned and self-reported exposures to VGDF were associated with measurements of subclinical ILD in community-dwelling adults.
590 $a School code: 0250.
650 4 $a Epidemiology. $3 568544
650 4 $a Environmental health. $3 543032
650 4 $a Medicine. $3 641104
690 $a 0766
690 $a 0470
690 $a 0564
710 2 $a University of Washington. $b Epidemiology. $3 3286238
773 0 $t Masters Abstracts International $g 57-05(E).
790 $a 0250
791 $a Master's
792 $a 2018
793 $a English
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10234542