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Amorphous drugs = benefits and chall...

Rams-Baron, Marzena.

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Amorphous drugs = benefits and challenges /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Amorphous drugs/ by Marzena Rams-Baron ... [et al.].
Reminder of title:	benefits and challenges /
other author:	Rams-Baron, Marzena.
Published:	Cham :Springer International Publishing : : 2018.,
Description:	ix, 230 p. :ill., digital ;24 cm.
[NT 15003449]:	Why amorphous drugs? -- Order vs. disorder in the solid state -- Amorphous drug solubility and absorption enhancement -- Amorphous drug preparation methods -- Physical instability - a key problem of amorphous drugs -- Amorphous drug formulation.
Contained By:	Springer eBooks
Subject:	Drug development. -
Online resource:	http://dx.doi.org/10.1007/978-3-319-72002-9
ISBN:	9783319720029

Amorphous drugs = benefits and challenges /
Amorphous drugsbenefits and challenges /[electronic resource] :by Marzena Rams-Baron ... [et al.]. - Cham :Springer International Publishing :2018. - ix, 230 p. :ill., digital ;24 cm.

Why amorphous drugs? -- Order vs. disorder in the solid state -- Amorphous drug solubility and absorption enhancement -- Amorphous drug preparation methods -- Physical instability - a key problem of amorphous drugs -- Amorphous drug formulation.

This book explains theoretical and technological aspects of amorphous drug formulations. It is intended for all those wishing to increase their knowledge in the field of amorphous pharmaceuticals. Conversion of crystalline material into the amorphous state, as described in this book, is a way to overcome limited water solubility of drug formulations, in this way enhancing the chemical activity and bioavailability inside the body. Written by experts from various fields and backgrounds, the book introduces to fundamental physical aspects (explaining differences between the ordered and the disordered solid states, the enhancement of solubility resulting from drugs amorphization, physical instability and how it can be overcome) as well as preparation and formulation procedures to produce and stabilize amorphous pharmaceuticals. Readers will thus gain a well-funded understanding and find a multi-faceted discussion of the properties and advantages of amorphous drugs and of the challenges in producing and stabilizing them. The book is an ideal source of information for researchers and students as well as professionals engaged in research and development of amorphous pharmaceutical products.

ISBN: 9783319720029

Standard No.: 10.1007/978-3-319-72002-9doiSubjects--Topical Terms:

716904
Drug development.

LC Class. No.: RM301.25

Dewey Class. No.: 615.19

Amorphous drugs = benefits and challenges /
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245 0 0 $a Amorphous drugs $h [electronic resource] : $b benefits and challenges / $c by Marzena Rams-Baron ... [et al.].
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2018.
300 $a ix, 230 p. : $b ill., digital ; $c 24 cm.
505 0 $a Why amorphous drugs? -- Order vs. disorder in the solid state -- Amorphous drug solubility and absorption enhancement -- Amorphous drug preparation methods -- Physical instability - a key problem of amorphous drugs -- Amorphous drug formulation.
520 $a This book explains theoretical and technological aspects of amorphous drug formulations. It is intended for all those wishing to increase their knowledge in the field of amorphous pharmaceuticals. Conversion of crystalline material into the amorphous state, as described in this book, is a way to overcome limited water solubility of drug formulations, in this way enhancing the chemical activity and bioavailability inside the body. Written by experts from various fields and backgrounds, the book introduces to fundamental physical aspects (explaining differences between the ordered and the disordered solid states, the enhancement of solubility resulting from drugs amorphization, physical instability and how it can be overcome) as well as preparation and formulation procedures to produce and stabilize amorphous pharmaceuticals. Readers will thus gain a well-funded understanding and find a multi-faceted discussion of the properties and advantages of amorphous drugs and of the challenges in producing and stabilizing them. The book is an ideal source of information for researchers and students as well as professionals engaged in research and development of amorphous pharmaceutical products.
650 0 $a Drug development. $3 716904
650 0 $a Drugs $x Bioavailability. $3 738670
650 1 4 $a Chemistry. $3 516420
650 2 4 $a Medicinal Chemistry. $3 892420
650 2 4 $a Pharmaceutical Sciences/Technology. $3 1001579
650 2 4 $a Phase Transitions and Multiphase Systems. $3 1066389
650 2 4 $a Thermodynamics. $3 517304
650 2 4 $a Ceramics, Glass, Composites, Natural Materials. $3 3205789
650 2 4 $a Biomedical Engineering. $3 720279
700 1 $a Rams-Baron, Marzena. $3 3301582
710 2 $a SpringerLink (Online service) $3 836513
773 0 $t Springer eBooks
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-72002-9
950 $a Chemistry and Materials Science (Springer-11644)