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RNA therapeutics

Garner, Amanda L.

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RNA therapeutics

Record Type:	Electronic resources : Monograph/item
Title/Author:	RNA therapeutics/ edited by Amanda L. Garner.
other author:	Garner, Amanda L.
Published:	Cham :Springer International Publishing : : 2018.,
Description:	vii, 259 p. :ill., digital ;24 cm.
[NT 15003449]:	Computational Tools for Design of Selective Small Molecules Targeting RNA: From Small Molecule Microarrays to Chemical Similarity Searching -- A Modular Approach to the Discovery and Affinity Maturation of Sequence-Selective RNA-Binding Compounds -- Structure-Based Discovery of Small Molecules Binding to RNA -- Approaches for the Discovery of Small Molecule Ligands Targeting microRNAs -- Viral RNA Targets and Their Small Molecule Ligands -- Drugging Pre-mRNA Splicing -- Targeting RNA G-Quadruplexes for Potential Therapeutic Applications -- The Therapeutic Targeting of Long Noncoding RNA -- Messenger RNA as a Novel Therapeutic Approach.
Contained By:	Springer eBooks
Subject:	Drug development. -
Online resource:	http://dx.doi.org/10.1007/978-3-319-68091-0
ISBN:	9783319680910

RNA therapeutics
RNA therapeutics[electronic resource] /edited by Amanda L. Garner. - Cham :Springer International Publishing :2018. - vii, 259 p. :ill., digital ;24 cm. - Topics in medicinal chemistry,271862-2461 ;. - Topics in medicinal chemistry ;27..

Computational Tools for Design of Selective Small Molecules Targeting RNA: From Small Molecule Microarrays to Chemical Similarity Searching -- A Modular Approach to the Discovery and Affinity Maturation of Sequence-Selective RNA-Binding Compounds -- Structure-Based Discovery of Small Molecules Binding to RNA -- Approaches for the Discovery of Small Molecule Ligands Targeting microRNAs -- Viral RNA Targets and Their Small Molecule Ligands -- Drugging Pre-mRNA Splicing -- Targeting RNA G-Quadruplexes for Potential Therapeutic Applications -- The Therapeutic Targeting of Long Noncoding RNA -- Messenger RNA as a Novel Therapeutic Approach.

Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.

ISBN: 9783319680910

Standard No.: 10.1007/978-3-319-68091-0doiSubjects--Topical Terms:

716904
Drug development.

LC Class. No.: RM301.25

Dewey Class. No.: 615.19

RNA therapeutics
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245 0 0 $a RNA therapeutics $h [electronic resource] / $c edited by Amanda L. Garner.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2018.
300 $a vii, 259 p. : $b ill., digital ; $c 24 cm.
490 1 $a Topics in medicinal chemistry, $x 1862-2461 ; $v 27
505 0 $a Computational Tools for Design of Selective Small Molecules Targeting RNA: From Small Molecule Microarrays to Chemical Similarity Searching -- A Modular Approach to the Discovery and Affinity Maturation of Sequence-Selective RNA-Binding Compounds -- Structure-Based Discovery of Small Molecules Binding to RNA -- Approaches for the Discovery of Small Molecule Ligands Targeting microRNAs -- Viral RNA Targets and Their Small Molecule Ligands -- Drugging Pre-mRNA Splicing -- Targeting RNA G-Quadruplexes for Potential Therapeutic Applications -- The Therapeutic Targeting of Long Noncoding RNA -- Messenger RNA as a Novel Therapeutic Approach.
520 $a Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.
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