東華大學圖書館 |

Language: English

Help

回圖書館首頁

手機版館藏查詢

Back

Switch To: Labeled | MARC Mode | ISBD

Environmental and Systemic Exposure ...

Frew, John A.

Linked to FindBook

Google Book

Amazon

博客來

Environmental and Systemic Exposure Assessment for Green Sturgeon Following Application of Imidacloprid for the Control of Burrowing Shrimp in Willapa Bay, Washington.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Environmental and Systemic Exposure Assessment for Green Sturgeon Following Application of Imidacloprid for the Control of Burrowing Shrimp in Willapa Bay, Washington./
Author:	Frew, John A.
Description:	96 p.
Notes:	Source: Dissertation Abstracts International, Volume: 75-05(E), Section: B.
Contained By:	Dissertation Abstracts International75-05B(E).
Subject:	Toxicology. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3608928
ISBN:	9781303674525

Environmental and Systemic Exposure Assessment for Green Sturgeon Following Application of Imidacloprid for the Control of Burrowing Shrimp in Willapa Bay, Washington.
Frew, John A.

Environmental and Systemic Exposure Assessment for Green Sturgeon Following Application of Imidacloprid for the Control of Burrowing Shrimp in Willapa Bay, Washington. - 96 p.

Source: Dissertation Abstracts International, Volume: 75-05(E), Section: B.

Thesis (Ph.D.)--University of Washington, 2013.

The neonicotinoid insecticide imidacloprid (IMI) has been proposed for the control of burrowing shrimp on oyster beds in Willapa Bay, Washington. Use of IMI may be denied if it is shown that ESA-listed green sturgeon are adversely affected as a result of exposure to the compound. Green sturgeon were found to feed opportunistically on IMI-impaired shrimp following test applications of the insecticide. Foraging activities could result in exposure to IMI in sediment pore water and from the consumption of contaminated shrimp. An exposure characterization revealed maximum IMI residue concentrations of 27.8 mug L-1 in pore water and 31.4 mug kg-1 in shrimp. Results from modeling branchial and dietary uptake indicated that pore water exposure would account for most of the systemic absorption of IMI. The 96-h median lethal toxicity (LC50) for surrogate juvenile white sturgeon was 124 mg L-1, indicating sturgeon do not possess extreme sensitivity to IMI. Controlled exposures to white sturgeon of maximum IMI field concentrations did not result in overt effects, but showed relatively long persistence of the chemical in plasma. Toxicokinetic studies were conducted with rainbow trout (RBT) to describe the disposition and elimination of IMI in fish. Results suggest no dose-dependence on kinetics following interarterial bolus injections of a low (44.7 mug kg-1) or high (250.0 mug kg-1) dose of IMI. Mean values for the steady-state volume of distribution (Vss) were 1561.9 and 1922.5 mL kg-1 for the low and high dose groups, respectively. Mean whole body clearance (CLB) was 20.5 mL h -1 kg-1 for both groups. The elimination half-life (t1/2) was 65.6 and 68.2 h for the low and high dose groups, respectively. Mass-balance analysis revealed that branchial clearance accounted for almost 50% of CLB . Measured tissue:plasma IMI residue concentration ratios in RBT and white sturgeon were comparable, suggesting that both species handle the chemical in a similar manner. The hazard quotient (HQ), the ratio of the maximum pore water concentration over the LC50 value, was two orders of magnitude below the threshold for potential effects. This implies that green sturgeon would be at minimal risk from exposure to IMI in Willapa Bay.

ISBN: 9781303674525Subjects--Topical Terms:

556884
Toxicology.

Environmental and Systemic Exposure Assessment for Green Sturgeon Following Application of Imidacloprid for the Control of Burrowing Shrimp in Willapa Bay, Washington.
LDR:03242nmm a2200289 4500 001 2115367
005 20170228070220.5
008 180830s2013 ||||||||||||||||| ||eng d
020 $a 9781303674525
035 $a (MiAaPQ)AAI3608928
035 $a AAI3608928
040 $a MiAaPQ $c MiAaPQ
100 1 $a Frew, John A. $3 3277016
245 1 0 $a Environmental and Systemic Exposure Assessment for Green Sturgeon Following Application of Imidacloprid for the Control of Burrowing Shrimp in Willapa Bay, Washington.
300 $a 96 p.
500 $a Source: Dissertation Abstracts International, Volume: 75-05(E), Section: B.
500 $a Adviser: Christian Grue.
502 $a Thesis (Ph.D.)--University of Washington, 2013.
520 $a The neonicotinoid insecticide imidacloprid (IMI) has been proposed for the control of burrowing shrimp on oyster beds in Willapa Bay, Washington. Use of IMI may be denied if it is shown that ESA-listed green sturgeon are adversely affected as a result of exposure to the compound. Green sturgeon were found to feed opportunistically on IMI-impaired shrimp following test applications of the insecticide. Foraging activities could result in exposure to IMI in sediment pore water and from the consumption of contaminated shrimp. An exposure characterization revealed maximum IMI residue concentrations of 27.8 mug L-1 in pore water and 31.4 mug kg-1 in shrimp. Results from modeling branchial and dietary uptake indicated that pore water exposure would account for most of the systemic absorption of IMI. The 96-h median lethal toxicity (LC50) for surrogate juvenile white sturgeon was 124 mg L-1, indicating sturgeon do not possess extreme sensitivity to IMI. Controlled exposures to white sturgeon of maximum IMI field concentrations did not result in overt effects, but showed relatively long persistence of the chemical in plasma. Toxicokinetic studies were conducted with rainbow trout (RBT) to describe the disposition and elimination of IMI in fish. Results suggest no dose-dependence on kinetics following interarterial bolus injections of a low (44.7 mug kg-1) or high (250.0 mug kg-1) dose of IMI. Mean values for the steady-state volume of distribution (Vss) were 1561.9 and 1922.5 mL kg-1 for the low and high dose groups, respectively. Mean whole body clearance (CLB) was 20.5 mL h -1 kg-1 for both groups. The elimination half-life (t1/2) was 65.6 and 68.2 h for the low and high dose groups, respectively. Mass-balance analysis revealed that branchial clearance accounted for almost 50% of CLB . Measured tissue:plasma IMI residue concentration ratios in RBT and white sturgeon were comparable, suggesting that both species handle the chemical in a similar manner. The hazard quotient (HQ), the ratio of the maximum pore water concentration over the LC50 value, was two orders of magnitude below the threshold for potential effects. This implies that green sturgeon would be at minimal risk from exposure to IMI in Willapa Bay.
590 $a School code: 0250.
650 4 $a Toxicology. $3 556884
650 4 $a Environmental health. $3 543032
650 4 $a Aquatic sciences. $3 3174300
690 $a 0383
690 $a 0470
690 $a 0792
710 2 $a University of Washington. $b Aquatic and Fishery Sciences. $3 2093042
773 0 $t Dissertation Abstracts International $g 75-05B(E).
790 $a 0250
791 $a Ph.D.
792 $a 2013
793 $a English
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3608928