東華大學圖書館 |

Language: English

Help

回圖書館首頁

手機版館藏查詢

Back

Switch To: Labeled | MARC Mode | ISBD

Mitochondrial DNA and diseases

Sun, Hongzhi.

Linked to FindBook

Google Book

Amazon

博客來

Mitochondrial DNA and diseases

Record Type:	Electronic resources : Monograph/item
Title/Author:	Mitochondrial DNA and diseases/ edited by Hongzhi Sun, Xiangdong Wang.
other author:	Sun, Hongzhi.
Published:	Singapore :Springer Singapore : : 2017.,
Description:	vii, 230 p. :ill., digital ;24 cm.
[NT 15003449]:	How far can mitochondrial DNA drive the disease? -- Mitochondrial DNA in lung cancer -- Approach, application and bioethics of mtDNA sequencing in cancer -- Roles of mitochondrial DNA signaling in immune responses -- Mitochondrial DNA in Telocytes -- Roles of mitochondrial DNA in energy metabolism -- The role of base excision repair in maintaining mitochondrial DNA stability -- Is mitochondrial cell fragility a cell weakness? -- Mitochondrial DNA methylation and related disease -- Beyond deubiquitylation: USP30-mediated regulation of mitochondrial homeostasis -- Metabolic regulation in mitochondria and drug resistance -- Mitochondrial Lon Protease and Cancer -- Regulatory roles of mitochondrial ribosome in lung diseases and single cell biology -- Epithelial mitochondrial dysfunction in lung disease.
Contained By:	Springer eBooks
Subject:	Mitochondrial DNA. -
Online resource:	http://dx.doi.org/10.1007/978-981-10-6674-0
ISBN:	9789811066740

Mitochondrial DNA and diseases
Mitochondrial DNA and diseases[electronic resource] /edited by Hongzhi Sun, Xiangdong Wang. - Singapore :Springer Singapore :2017. - vii, 230 p. :ill., digital ;24 cm. - Advances in experimental medicine and biology,v.10380065-2598 ;. - Advances in experimental medicine and biology ;v.1038..

How far can mitochondrial DNA drive the disease? -- Mitochondrial DNA in lung cancer -- Approach, application and bioethics of mtDNA sequencing in cancer -- Roles of mitochondrial DNA signaling in immune responses -- Mitochondrial DNA in Telocytes -- Roles of mitochondrial DNA in energy metabolism -- The role of base excision repair in maintaining mitochondrial DNA stability -- Is mitochondrial cell fragility a cell weakness? -- Mitochondrial DNA methylation and related disease -- Beyond deubiquitylation: USP30-mediated regulation of mitochondrial homeostasis -- Metabolic regulation in mitochondria and drug resistance -- Mitochondrial Lon Protease and Cancer -- Regulatory roles of mitochondrial ribosome in lung diseases and single cell biology -- Epithelial mitochondrial dysfunction in lung disease.

The book describes molecular principles and mechanisms by which mitochondrial DNA (mtDNA) can drive the occurrence of diseases and the latest understanding of mtDNA biology. The book explores roles of mtDNA mutation and genetic changes in cancer, with a special focus on lung cancer, and the significance of approach, application, and bioethics of mtDNA sequencing. Authors made a great effort to overview roles of mtDNA signaling pathways, base excision repair, methylation, USP30-mediated regulation, mitochondrial ribosome, autophagy pathways, or ROS-dependent signaling in the pathogenesis, diagnosis, prevention and treatment of diseases. It also demonstrates the importance of basic mitochondrial genetics and the relationship between mutations and disease phenotypes and ageing. This book covers not only the basic information of mtDNA, the relationship of mtDNA and disease, but also mtDNA in stem cell and mitochondria and metabolism etc. The book is written for biological and clinical students and researchers in the field of mtDNA-associated diseases.

ISBN: 9789811066740

Standard No.: 10.1007/978-981-10-6674-0doiSubjects--Topical Terms:

558956
Mitochondrial DNA.

LC Class. No.: QP624.5.M58

Dewey Class. No.: 572.869

Mitochondrial DNA and diseases
LDR:02905nmm a2200325 a 4500 001 2112244
003 DE-He213
005 20180511115523.0
006 m d
007 cr nn 008maaau
008 180719s2017 si s 0 eng d
020 $a 9789811066740 $q (electronic bk.)
020 $a 9789811066733 $q (paper)
024 7 $a 10.1007/978-981-10-6674-0 $2 doi
035 $a 978-981-10-6674-0
040 $a GP $c GP
041 0 $a eng
050 4 $a QP624.5.M58
072 7 $a PSF $2 bicssc
072 7 $a SCI049000 $2 bisacsh
082 0 4 $a 572.869 $2 23
090 $a QP624.5.M58 $b M684 2017
245 0 0 $a Mitochondrial DNA and diseases $h [electronic resource] / $c edited by Hongzhi Sun, Xiangdong Wang.
260 $a Singapore : $b Springer Singapore : $b Imprint: Springer, $c 2017.
300 $a vii, 230 p. : $b ill., digital ; $c 24 cm.
490 1 $a Advances in experimental medicine and biology, $x 0065-2598 ; $v v.1038
505 0 $a How far can mitochondrial DNA drive the disease? -- Mitochondrial DNA in lung cancer -- Approach, application and bioethics of mtDNA sequencing in cancer -- Roles of mitochondrial DNA signaling in immune responses -- Mitochondrial DNA in Telocytes -- Roles of mitochondrial DNA in energy metabolism -- The role of base excision repair in maintaining mitochondrial DNA stability -- Is mitochondrial cell fragility a cell weakness? -- Mitochondrial DNA methylation and related disease -- Beyond deubiquitylation: USP30-mediated regulation of mitochondrial homeostasis -- Metabolic regulation in mitochondria and drug resistance -- Mitochondrial Lon Protease and Cancer -- Regulatory roles of mitochondrial ribosome in lung diseases and single cell biology -- Epithelial mitochondrial dysfunction in lung disease.
520 $a The book describes molecular principles and mechanisms by which mitochondrial DNA (mtDNA) can drive the occurrence of diseases and the latest understanding of mtDNA biology. The book explores roles of mtDNA mutation and genetic changes in cancer, with a special focus on lung cancer, and the significance of approach, application, and bioethics of mtDNA sequencing. Authors made a great effort to overview roles of mtDNA signaling pathways, base excision repair, methylation, USP30-mediated regulation, mitochondrial ribosome, autophagy pathways, or ROS-dependent signaling in the pathogenesis, diagnosis, prevention and treatment of diseases. It also demonstrates the importance of basic mitochondrial genetics and the relationship between mutations and disease phenotypes and ageing. This book covers not only the basic information of mtDNA, the relationship of mtDNA and disease, but also mtDNA in stem cell and mitochondria and metabolism etc. The book is written for biological and clinical students and researchers in the field of mtDNA-associated diseases.
650 0 $a Mitochondrial DNA. $3 558956
650 0 $a Mitochondrial DNA $x Abnormalities. $3 841795
650 1 4 $a Life Sciences. $3 890838
650 2 4 $a Cell Biology. $3 892383
650 2 4 $a Human Genetics. $3 891169
700 1 $a Sun, Hongzhi. $3 1285306
700 1 $a Wang, Xiangdong. $3 2139059
710 2 $a SpringerLink (Online service) $3 836513
773 0 $t Springer eBooks
830 0 $a Advances in experimental medicine and biology ; $v v.1038. $3 3269748
856 4 0 $u http://dx.doi.org/10.1007/978-981-10-6674-0
950 $a Biomedical and Life Sciences (Springer-11642)