東華大學圖書館 |

Language: English

Help

回圖書館首頁

手機版館藏查詢

Back

Switch To: Labeled | MARC Mode | ISBD

Isolation and molecular characteriza...

Magbanua, Mark Jesus M.

Linked to FindBook

Google Book

Amazon

博客來

Isolation and molecular characterization of circulating tumor cells

Record Type:	Electronic resources : Monograph/item
Title/Author:	Isolation and molecular characterization of circulating tumor cells/ edited by Mark Jesus M. Magbanua, John W. Park.
other author:	Magbanua, Mark Jesus M.
Published:	Cham :Springer International Publishing : : 2017.,
Description:	xvi, 301 p. :ill., digital ;24 cm.
[NT 15003449]:	Preface -- Circulating Tumor Cells as Cancer Biomarkers -- Strategies for Isolation and Molecular Profiling of Circulating Tumor Cells -- Aptamer-Based Methods for Detection of Circulating Tumor Cells and Their Potential for Personalized Diagnostics -- Development of a Protocol for Single-Cell Analysis of Circulating Tumor Cells in Patients with Solid Tumors -- Flow Cytometric Methods for Circulating Tumor Cell Isolation and Molecular Analysis -- Enrichment and Detection of Circulating Tumor Cells and Other Rare Cell Populations by Microfluidic Filtration -- Detection and Enumeration of Circulating Tumor Cells with Invasive Phenotype -- Molecular Profiling and Significance of Circulating Tumor Cell Based Genetic Signatures -- Detection of Gene-Rearrangements in Circulating Tumor Cells: Examples of ALK-, ROS1-, RET-Rearrangements in Non-Small-Cell Lung Cancer and ERG-Rearrangements in Prostate Cancer -- Enrichment, Isolation, and Molecular Characterization of EpCAM-Negative Circulating Tumor Cells -- Expression of Epithelial Mesenchymal Transition and Cancer Stem Cell Markers in Circulating Tumor Cells.
Contained By:	Springer eBooks
Subject:	Metastasis. -
Online resource:	http://dx.doi.org/10.1007/978-3-319-55947-6
ISBN:	9783319559476

Isolation and molecular characterization of circulating tumor cells
Isolation and molecular characterization of circulating tumor cells[electronic resource] /edited by Mark Jesus M. Magbanua, John W. Park. - Cham :Springer International Publishing :2017. - xvi, 301 p. :ill., digital ;24 cm. - Advances in experimental medicine and biology,v.9940065-2598 ;. - Advances in experimental medicine and biology ;v.994..

Preface -- Circulating Tumor Cells as Cancer Biomarkers -- Strategies for Isolation and Molecular Profiling of Circulating Tumor Cells -- Aptamer-Based Methods for Detection of Circulating Tumor Cells and Their Potential for Personalized Diagnostics -- Development of a Protocol for Single-Cell Analysis of Circulating Tumor Cells in Patients with Solid Tumors -- Flow Cytometric Methods for Circulating Tumor Cell Isolation and Molecular Analysis -- Enrichment and Detection of Circulating Tumor Cells and Other Rare Cell Populations by Microfluidic Filtration -- Detection and Enumeration of Circulating Tumor Cells with Invasive Phenotype -- Molecular Profiling and Significance of Circulating Tumor Cell Based Genetic Signatures -- Detection of Gene-Rearrangements in Circulating Tumor Cells: Examples of ALK-, ROS1-, RET-Rearrangements in Non-Small-Cell Lung Cancer and ERG-Rearrangements in Prostate Cancer -- Enrichment, Isolation, and Molecular Characterization of EpCAM-Negative Circulating Tumor Cells -- Expression of Epithelial Mesenchymal Transition and Cancer Stem Cell Markers in Circulating Tumor Cells.

The past decade has seen remarkable progress in elucidating the clinical relevance of circulating tumor cells (CTCs) Evidence from numerous clinical studies has unequivocally demonstrated the importance of CTCs as harbingers of poor outcome. Despite these advances, the molecular nature of CTCs remains elusive. This is in part due to the difficulty in isolating pure CTCs away from blood cells. Recent advancements in rare-cell technology have provided solutions to the once daunting task of isolating extremely rare CTCs in the blood of cancer patients. This book presents different novel approaches for detection and purification of CTCs. In addition, the readers are introduced to new technologies for molecular profiling of CTCs, including techniques to overcome limitations posed by the paucity of cells and the biomolecules available for downstream molecular analysis. This book is particularly relevant to scientists and academicians who are interested in the field of CTC research. It provides an overview of the recent technological advances in CTC isolation and profiling. This work also includes discussions on pertinent issues regarding the biology of CTCs, and their potential utility as liquid biopsy for personalized medicine. We hope that this book stimulate further research and help advance our understanding of the molecular biology of CTCs.

ISBN: 9783319559476

Standard No.: 10.1007/978-3-319-55947-6doiSubjects--Topical Terms:

818532
Metastasis.

LC Class. No.: RC269.5

Dewey Class. No.: 616.99407

Isolation and molecular characterization of circulating tumor cells
LDR:03545nmm a2200325 a 4500 001 2100167
003 DE-He213
005 20170530142439.0
006 m d
007 cr nn 008maaau
008 180119s2017 gw s 0 eng d
020 $a 9783319559476 $q (electronic bk.)
020 $a 9783319559469 $q (paper)
024 7 $a 10.1007/978-3-319-55947-6 $2 doi
035 $a 978-3-319-55947-6
040 $a GP $c GP
041 0 $a eng
050 4 $a RC269.5
072 7 $a MJCL $2 bicssc
072 7 $a MED062000 $2 bisacsh
082 0 4 $a 616.99407 $2 23
090 $a RC269.5 $b .I85 2017
245 0 0 $a Isolation and molecular characterization of circulating tumor cells $h [electronic resource] / $c edited by Mark Jesus M. Magbanua, John W. Park.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2017.
300 $a xvi, 301 p. : $b ill., digital ; $c 24 cm.
490 1 $a Advances in experimental medicine and biology, $x 0065-2598 ; $v v.994
505 0 $a Preface -- Circulating Tumor Cells as Cancer Biomarkers -- Strategies for Isolation and Molecular Profiling of Circulating Tumor Cells -- Aptamer-Based Methods for Detection of Circulating Tumor Cells and Their Potential for Personalized Diagnostics -- Development of a Protocol for Single-Cell Analysis of Circulating Tumor Cells in Patients with Solid Tumors -- Flow Cytometric Methods for Circulating Tumor Cell Isolation and Molecular Analysis -- Enrichment and Detection of Circulating Tumor Cells and Other Rare Cell Populations by Microfluidic Filtration -- Detection and Enumeration of Circulating Tumor Cells with Invasive Phenotype -- Molecular Profiling and Significance of Circulating Tumor Cell Based Genetic Signatures -- Detection of Gene-Rearrangements in Circulating Tumor Cells: Examples of ALK-, ROS1-, RET-Rearrangements in Non-Small-Cell Lung Cancer and ERG-Rearrangements in Prostate Cancer -- Enrichment, Isolation, and Molecular Characterization of EpCAM-Negative Circulating Tumor Cells -- Expression of Epithelial Mesenchymal Transition and Cancer Stem Cell Markers in Circulating Tumor Cells.
520 $a The past decade has seen remarkable progress in elucidating the clinical relevance of circulating tumor cells (CTCs) Evidence from numerous clinical studies has unequivocally demonstrated the importance of CTCs as harbingers of poor outcome. Despite these advances, the molecular nature of CTCs remains elusive. This is in part due to the difficulty in isolating pure CTCs away from blood cells. Recent advancements in rare-cell technology have provided solutions to the once daunting task of isolating extremely rare CTCs in the blood of cancer patients. This book presents different novel approaches for detection and purification of CTCs. In addition, the readers are introduced to new technologies for molecular profiling of CTCs, including techniques to overcome limitations posed by the paucity of cells and the biomolecules available for downstream molecular analysis. This book is particularly relevant to scientists and academicians who are interested in the field of CTC research. It provides an overview of the recent technological advances in CTC isolation and profiling. This work also includes discussions on pertinent issues regarding the biology of CTCs, and their potential utility as liquid biopsy for personalized medicine. We hope that this book stimulate further research and help advance our understanding of the molecular biology of CTCs.
650 0 $a Metastasis. $3 818532
650 1 4 $a Biomedicine. $3 890831
650 2 4 $a Cancer Research. $3 891172
700 1 $a Magbanua, Mark Jesus M. $3 3241617
700 1 $a Park, John W. $3 3241618
710 2 $a SpringerLink (Online service) $3 836513
773 0 $t Springer eBooks
830 0 $a Advances in experimental medicine and biology ; $v v.994. $3 3241619
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-55947-6
950 $a Biomedical and Life Sciences (Springer-11642)