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Energy expenditure in children with ...

Chavoya, Frank A.

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Energy expenditure in children with Prader-Willi Syndrome compared to lean and obese non-syndromal children while walking on a treadmill.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Energy expenditure in children with Prader-Willi Syndrome compared to lean and obese non-syndromal children while walking on a treadmill./
作者:	Chavoya, Frank A.
面頁冊數:	55 p.
附註:	Source: Masters Abstracts International, Volume: 55-02.
Contained By:	Masters Abstracts International55-02(E).
標題:	Kinesiology. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1604959
ISBN:	9781339298306

Energy expenditure in children with Prader-Willi Syndrome compared to lean and obese non-syndromal children while walking on a treadmill.
Chavoya, Frank A.

Energy expenditure in children with Prader-Willi Syndrome compared to lean and obese non-syndromal children while walking on a treadmill. - 55 p.

Source: Masters Abstracts International, Volume: 55-02.

Thesis (M.S.)--California State University, Fullerton, 2016.

Introduction: Prader-Willi Syndrome (PWS) is a complex genetic disorder caused by a deletion of the paternal chromosome 15. PWS is characterized by increased body fat, hypotonia, growth hormone (GH) deficiency, motor and cognitive disabilities, and hyperphagia, potentially resulting in obesity. Purpose: This study measured and compared the amount of calories spent while walking in PWS and controls. Methods: Participants included 8 children with PWS (7 were on growth hormone replacement therapy [GHRT], mean age = 11.1+/-0.8 y; body mass = 44.7+/-11.7 kg; height = 147.8+/-8.2 cm; body fat = 37.2+/-11.4 %; lean mass = 26.4+/-4.3 kg), 9 lean children (mean age = 9.8+/-2.0 y; body mass = 35.4+/-11.3 kg; height = 142.9+/-20.5 cm; body fat = 22.2+/-8.6 %; lean mass = 25.5+/-11.6 kg), and 10 obese children (mean age = 10.6+/-1.1 y; body mass = 62.1+/-14.6 kg; height = 151.1+/-9.6 cm; body fat = 44.4+/-3.7 %; lean mass = 33.3+/-5.1 kg). Lean body mass (LBM) and fat mass (FM) were measured with dual x-ray absorptiometry (DXA). Participants walked for three 5-minute bouts on a treadmill at 2.0, 2.5, and 3.0 mph, with a 6-minute seated rest period in between speeds. Expired gases were analyzed for minutes 4-5 of each speed. Results: There were no group by time interactions for any of the variables of interest. PWS had a higher VO2 ml&dot;kg -1&dot;min-1 than obese (p=0.041), but similar to lean (p=1.000); PWS exhibited a greater caloric expenditure in kcal&dot; -1&dot;min-1 than obese (p=0.028), but similar to lean (p=1.000). No other differences were found among the PWS and control groups during walking for VO2 when expressed in L&dot;min-1 or ml&dot;kgLMB-1&dot;min-1, caloric expenditure when expressed in kcal/min or kcal&dot;kgLBM-1&dot;min -1, or metabolic equivalents. Conclusion: The results of this study suggest that children with PWS are spending similar calories as lean controls of comparable body mass while walking. Thus, the difference in body fat does not appear to affect calories spent doing the same absolute work in PWS.

ISBN: 9781339298306Subjects--Topical Terms:

517627
Kinesiology.

Energy expenditure in children with Prader-Willi Syndrome compared to lean and obese non-syndromal children while walking on a treadmill.
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245 1 0 $a Energy expenditure in children with Prader-Willi Syndrome compared to lean and obese non-syndromal children while walking on a treadmill.
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500 $a Source: Masters Abstracts International, Volume: 55-02.
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520 $a Introduction: Prader-Willi Syndrome (PWS) is a complex genetic disorder caused by a deletion of the paternal chromosome 15. PWS is characterized by increased body fat, hypotonia, growth hormone (GH) deficiency, motor and cognitive disabilities, and hyperphagia, potentially resulting in obesity. Purpose: This study measured and compared the amount of calories spent while walking in PWS and controls. Methods: Participants included 8 children with PWS (7 were on growth hormone replacement therapy [GHRT], mean age = 11.1+/-0.8 y; body mass = 44.7+/-11.7 kg; height = 147.8+/-8.2 cm; body fat = 37.2+/-11.4 %; lean mass = 26.4+/-4.3 kg), 9 lean children (mean age = 9.8+/-2.0 y; body mass = 35.4+/-11.3 kg; height = 142.9+/-20.5 cm; body fat = 22.2+/-8.6 %; lean mass = 25.5+/-11.6 kg), and 10 obese children (mean age = 10.6+/-1.1 y; body mass = 62.1+/-14.6 kg; height = 151.1+/-9.6 cm; body fat = 44.4+/-3.7 %; lean mass = 33.3+/-5.1 kg). Lean body mass (LBM) and fat mass (FM) were measured with dual x-ray absorptiometry (DXA). Participants walked for three 5-minute bouts on a treadmill at 2.0, 2.5, and 3.0 mph, with a 6-minute seated rest period in between speeds. Expired gases were analyzed for minutes 4-5 of each speed. Results: There were no group by time interactions for any of the variables of interest. PWS had a higher VO2 ml&dot;kg -1&dot;min-1 than obese (p=0.041), but similar to lean (p=1.000); PWS exhibited a greater caloric expenditure in kcal&dot; -1&dot;min-1 than obese (p=0.028), but similar to lean (p=1.000). No other differences were found among the PWS and control groups during walking for VO2 when expressed in L&dot;min-1 or ml&dot;kgLMB-1&dot;min-1, caloric expenditure when expressed in kcal/min or kcal&dot;kgLBM-1&dot;min -1, or metabolic equivalents. Conclusion: The results of this study suggest that children with PWS are spending similar calories as lean controls of comparable body mass while walking. Thus, the difference in body fat does not appear to affect calories spent doing the same absolute work in PWS.
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