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Quality of life and depressive sympt...

Zhu, Hao.

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Quality of life and depressive symptoms as predictors of participant adherence in a randomized trial conducted among older adults at risk of mobility disability.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Quality of life and depressive symptoms as predictors of participant adherence in a randomized trial conducted among older adults at risk of mobility disability./
Author:	Zhu, Hao.
Description:	64 p.
Notes:	Source: Masters Abstracts International, Volume: 54-04.
Contained By:	Masters Abstracts International54-04(E).
Subject:	Medicine. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1585238
ISBN:	9781321616750

Quality of life and depressive symptoms as predictors of participant adherence in a randomized trial conducted among older adults at risk of mobility disability.
Zhu, Hao.

Quality of life and depressive symptoms as predictors of participant adherence in a randomized trial conducted among older adults at risk of mobility disability. - 64 p.

Source: Masters Abstracts International, Volume: 54-04.

Thesis (M.A.)--Boston University, 2015.

Poor adherence is an issue in clinical trials with a striking magnitude and negative impact. Recent studies indicate that two widely used clinical screening tools, Short Form (SF-36) Health Survey and Center for Epidemiologic Studies Depression Scale (CES-D) can be used as risk stratifiers to identify participants who require extra interaction to stay adherent in specific population. There is, however, little evidence to support the implication of these tools in elderly individuals with mobility limitations. These individuals may be particularly vulnerable to the risks of poor adherence in the context of a demanding interventional scheme. This study fulfills this gap by analyzing the quality of life and adherence data from the VIVE2 study, which is a double-blinded randomized explanatory clinical trial assessing the benefits of nutritional supplements and daily exercises to elderly patients with mobility limitation. The preliminary results showed that in clinical studies targeting elderly population with mobility limitations, the summary scores of SF-36 trended to have weak and nonsignificant association with a decreased risk of poor adherence to both exercise completion and product consumption while CES-D has no association.

ISBN: 9781321616750Subjects--Topical Terms:

641104
Medicine.

Quality of life and depressive symptoms as predictors of participant adherence in a randomized trial conducted among older adults at risk of mobility disability.
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245 1 0 $a Quality of life and depressive symptoms as predictors of participant adherence in a randomized trial conducted among older adults at risk of mobility disability.
300 $a 64 p.
500 $a Source: Masters Abstracts International, Volume: 54-04.
500 $a Advisers: Janice Weinberg; Thomas G. Travison.
502 $a Thesis (M.A.)--Boston University, 2015.
520 $a Poor adherence is an issue in clinical trials with a striking magnitude and negative impact. Recent studies indicate that two widely used clinical screening tools, Short Form (SF-36) Health Survey and Center for Epidemiologic Studies Depression Scale (CES-D) can be used as risk stratifiers to identify participants who require extra interaction to stay adherent in specific population. There is, however, little evidence to support the implication of these tools in elderly individuals with mobility limitations. These individuals may be particularly vulnerable to the risks of poor adherence in the context of a demanding interventional scheme. This study fulfills this gap by analyzing the quality of life and adherence data from the VIVE2 study, which is a double-blinded randomized explanatory clinical trial assessing the benefits of nutritional supplements and daily exercises to elderly patients with mobility limitation. The preliminary results showed that in clinical studies targeting elderly population with mobility limitations, the summary scores of SF-36 trended to have weak and nonsignificant association with a decreased risk of poor adherence to both exercise completion and product consumption while CES-D has no association.
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