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Development of Field-Portable Biosen...

Alkasir, Ramiz S. J.

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Development of Field-Portable Biosensors for the Detection of Phenols in Aquatic and Aerosol Environments.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Development of Field-Portable Biosensors for the Detection of Phenols in Aquatic and Aerosol Environments./
Author:	Alkasir, Ramiz S. J.
Description:	164 p.
Notes:	Source: Dissertation Abstracts International, Volume: 76-10(E), Section: B.
Contained By:	Dissertation Abstracts International76-10B(E).
Subject:	Analytical chemistry. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3707562
ISBN:	9781321822380

Development of Field-Portable Biosensors for the Detection of Phenols in Aquatic and Aerosol Environments.
Alkasir, Ramiz S. J.

Development of Field-Portable Biosensors for the Detection of Phenols in Aquatic and Aerosol Environments. - 164 p.

Source: Dissertation Abstracts International, Volume: 76-10(E), Section: B.

Thesis (Ph.D.)--Clarkson University, 2015.

Phenolic compounds including phenol and phenol derivatives such as bisphenol A (BPA), catechol and cresols are widely-used industrial by-products that can accumulate in the environment and the ecological food chain through consumption or uptake. Their presence in air, water and food matrices pose increasing risks to the human health and the environment. Conventional methods for the detection of these chemicals include laboratory-based spectrophotometric and chromatographic methods. Simple, easy-to-operate and inexpensive methods for screening and rapid detection of these compounds are needed to simplify field monitoring and evaluate exposure risks associated with the presence of these chemicals.

ISBN: 9781321822380Subjects--Topical Terms:

3168300
Analytical chemistry.

Development of Field-Portable Biosensors for the Detection of Phenols in Aquatic and Aerosol Environments.
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100 1 $a Alkasir, Ramiz S. J. $3 3178867
245 1 0 $a Development of Field-Portable Biosensors for the Detection of Phenols in Aquatic and Aerosol Environments.
300 $a 164 p.
500 $a Source: Dissertation Abstracts International, Volume: 76-10(E), Section: B.
500 $a Adviser: Silvana Andreescu.
502 $a Thesis (Ph.D.)--Clarkson University, 2015.
520 $a Phenolic compounds including phenol and phenol derivatives such as bisphenol A (BPA), catechol and cresols are widely-used industrial by-products that can accumulate in the environment and the ecological food chain through consumption or uptake. Their presence in air, water and food matrices pose increasing risks to the human health and the environment. Conventional methods for the detection of these chemicals include laboratory-based spectrophotometric and chromatographic methods. Simple, easy-to-operate and inexpensive methods for screening and rapid detection of these compounds are needed to simplify field monitoring and evaluate exposure risks associated with the presence of these chemicals.
520 $a This thesis describes the development, characterization and application of two types of portable biosensors for field detection of phenolic compounds. The first part will introduce a new type of paper-based colorimetric method that is portable, ease-of-use, inexpensive and suitable for field analysis. The sensing platform has a build-in detection mechanism with all the reagents needed for detection immobilized on paper. The sensor is based on a layer-by-layer assembly consisting of successive layers of complementary charged polyelectrolytes with a physically entrapped enzyme in between the layers. The colorimetric response is concentration dependent, with a detection limit of 1.0 mug/L for each of the phenolic compounds tested. This part will conclude with a demonstration of field capabilities, validation and deployment of these sensors for the detection of BPA in indoor household dust. BPA was found in household dust in the concentration range of 0.05 to 3.87 mug/g in 57 samples of indoor dust collected from four different houses and a day care center in Potsdam, New York. The second part will describe an electrochemical screen-printing biosensor based on enzyme functionalized nanoparticles. The biosensor allowed fast and sensitive detection of as little as 0.0016 mug/mL in less than 30 sec. The thesis demonstrates assessment of phenolic derivatives using biosensing methods, and possibility of replacing conventional methods with these methods.
590 $a School code: 0049.
650 4 $a Analytical chemistry. $3 3168300
650 4 $a Environmental health. $3 543032
650 4 $a Biomedical engineering. $3 535387
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710 2 $a Clarkson University. $b Chemistry. $3 3177158
773 0 $t Dissertation Abstracts International $g 76-10B(E).
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791 $a Ph.D.
792 $a 2015
793 $a English
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3707562