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Selected Topics in Statistical Compu...
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Zhang, Yiwen.
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Selected Topics in Statistical Computing.
Record Type:
Electronic resources : Monograph/item
Title/Author:
Selected Topics in Statistical Computing./
Author:
Zhang, Yiwen.
Description:
214 p.
Notes:
Source: Dissertation Abstracts International, Volume: 76-04(E), Section: B.
Contained By:
Dissertation Abstracts International76-04B(E).
Subject:
Statistics. -
Online resource:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3647716
ISBN:
9781321414660
Selected Topics in Statistical Computing.
Zhang, Yiwen.
Selected Topics in Statistical Computing.
- 214 p.
Source: Dissertation Abstracts International, Volume: 76-04(E), Section: B.
Thesis (Ph.D.)--North Carolina State University, 2014.
This item must not be sold to any third party vendors.
As the connection between statistical models and the real data, optimization methods draw attentions from both academia and industries. Since advances in technology enable easier data collection, complex models are in demand to cope with data that have complex structures; efficient optimization methods are needed to perform analysis on large and ever-growing volumes of data. In this dissertation, we investigate the optimization methods that target at these two issues. The first half of the thesis focuses on developing and implementing optimization algorithms for multivariate generalized linear models (MGLM), while the second half addresses the problems with large data sets.
ISBN: 9781321414660Subjects--Topical Terms:
517247
Statistics.
Selected Topics in Statistical Computing.
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Source: Dissertation Abstracts International, Volume: 76-04(E), Section: B.
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Adviser: Hua Zhou.
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Thesis (Ph.D.)--North Carolina State University, 2014.
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This item must not be sold to any third party vendors.
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As the connection between statistical models and the real data, optimization methods draw attentions from both academia and industries. Since advances in technology enable easier data collection, complex models are in demand to cope with data that have complex structures; efficient optimization methods are needed to perform analysis on large and ever-growing volumes of data. In this dissertation, we investigate the optimization methods that target at these two issues. The first half of the thesis focuses on developing and implementing optimization algorithms for multivariate generalized linear models (MGLM), while the second half addresses the problems with large data sets.
520
$a
Data with multivariate count responses frequently occur in modern applications. The commonly used multinomial-logit model is limiting due to its restrictive mean-variance structure. For instance, analysis of count data from the recent RNA-seq technology by the multinomial-logit model leads to serious errors in hypothesis testing. The ubiquity of over-dispersion and complex correlation structures among multivariate counts call for more flexible regression models. In this dissertation, we study some generalized linear models with multivariate count responses that incorporate various correlation structures among the components of the response vector. Current literature lacks treatment of these models, partly due to the fact that they do not belong to the natural exponential family. We derive stable optimization algorithms under the minorization-maximization (MM) principle. Parameter estimation, testing, and variable selection for these models are treated in a unifying framework. The regression models are compared on both synthetic and real RNA-seq data.
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Traditional iterative optimization algorithms require the whole data set to be available in memory for each iteration. When analyzing large data sets, this optimization scheme makes the computation sensitive to the memory limit. We investigate the online optimization algorithms that provide elegant solutions to the analysis on large data sets. Instead of keeping the whole data set in memory, online algorithms only keep a small batch of data points in memory at each iteration, and process every data point once. We focus on adapting the MM algorithm to the online scheme.
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http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3647716
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